Search Results - "Moranvillier, Isabelle"

High Clinical Value of Liquid Biopsy to Detect Circulating Tumor Cells and Tumor Exosomes in Pancreatic Ductal Adenocarcinoma Patients Eligible for Up-Front Surgery by Buscail, Etienne, Alix-Panabières, Catherine, Quincy, Pascaline, Cauvin, Thomas, Chauvet, Alexandre, Degrandi, Olivier, Caumont, Charline, Verdon, Séverine, Lamrissi, Isabelle, Moranvillier, Isabelle, Buscail, Camille, Marty, Marion, Laurent, Christophe, Vendrely, Véronique, Moreau-Gaudry, François, Bedel, Aurélie, Dabernat, Sandrine, Chiche, Laurence

“…Expediting the diagnosis of pancreatic ductal adenocarcinoma (PDAC) would benefit care management, especially for the start of treatments requiring…”
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CD63-GPC1-Positive Exosomes Coupled with CA19-9 Offer Good Diagnostic Potential for Resectable Pancreatic Ductal Adenocarcinoma by Buscail, Etienne, Chauvet, Alexandre, Quincy, Pascaline, Degrandi, Olivier, Buscail, Camille, Lamrissi, Isabelle, Moranvillier, Isabelle, Caumont, Charline, Verdon, Severine, Brisson, Alain, Marty, Marion, Chiche, Laurence, Laurent, Christophe, Vendrely, Veronique, Moreau-Gaudry, François, Bedel, Aurelie, Dabernat, Sandrine

“…Tumor-released extracellular vesicles (EVs) contain tumor-specific cargo distinguishing them from healthy EVs, and making them eligible as circulating…”
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Differential Uridyl-diphosphate-Glucuronosyl Transferase 1A enzymatic arsenal explains the specific cytotoxicity of resveratrol towards tumor colorectal cells by Amintas, Samuel, Beaumont, Pauline, Dupin, Charles, Moranvillier, Isabelle, Lamrissi, Isabelle, Patel, Elie, Fernandez, Benjamin, Bibeyran, Alice, Boutin, Julian, Richard, Tristan, Krisa, Stéphanie, Moreau-Gaudry, François, Bedel, Aurélie, Cappellen, David, Pinson, Benoît, Vendrely, Véronique, Dabernat, Sandrine

“…[Display omitted] •Resveratrol differential effect in healthy and cancer cells is poorly understood.•UGT1A8/1A10 enzymes conjugate resveratrol into non-toxic…”
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Generation of induced pluripotent stem cells-derived hepatocyte-like cells for ex vivo gene therapy of primary hyperoxaluria type 1 by Estève, Julie, Blouin, Jean-Marc, Lalanne, Magalie, Azzi-Martin, Lamia, Dubus, Pierre, Bidet, Audrey, Harambat, Jérôme, Llanas, Brigitte, Moranvillier, Isabelle, Bedel, Aurélie, Moreau-Gaudry, François, Richard, Emmanuel

“…Primary hyperoxaluria type 1 (PH1) is a rare autosomal recessive disorder of the liver metabolism due to functional deficiency of the peroxisomal enzyme…”
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Metastasis suppressor NM23 limits oxidative stress in mammals by preventing activation of stress‐activated protein kinases/JNKs through its nucleoside diphosphate kinase activity by Peuchant, Evelyne, Bats, Marie‐Lise, Moranvillier, Isabelle, Lepoivre, Michel, Guitton, Jérôme, Wendum, Dominique, Lacombe, Marie‐Lise, Moreau‐Gaudry, François, Boissan, Mathieu, Dabernat, Sandrine

“…NME1 (nonmetastatic expressed 1) gene, which encodes nucleoside diphosphate kinase (NDPK) A [also known as nonmetastatic clone 23 (NM23)‐H1 in humans and…”
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Preventing Pluripotent Cell Teratoma in Regenerative Medicine Applied to Hematology Disorders by Bedel, Aurelie, Beliveau, François, Lamrissi‐Garcia, Isabelle, Rousseau, Benoit, Moranvillier, Isabelle, Rucheton, Benoit, Guyonnet‐Dupérat, Veronique, Cardinaud, Bruno, de Verneuil, Hubert, Moreau‐Gaudry, François, Dabernat, Sandrine

“…Iatrogenic tumorigenesis is a major limitation for the use of human induced pluripotent stem cells (hiPSCs) in hematology. The teratoma risk comes from the…”
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The anti-metastatic nm23-1 gene is needed for the final step of mammary duct maturation of the mouse nipple by Deplagne, Camille, Peuchant, Evelyne, Moranvillier, Isabelle, Dubus, Pierre, Dabernat, Sandrine

“…Nm23/NDP kinases are multifunctional enzymes involved in the general homeostasis of triphosphate nucleosides. Numerous studies have shown that NDPKs also serve…”
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In vivo gene transfer targeting in pancreatic adenocarcinoma with cell surface antigens by Lafitte, Marie, Rousseau, Benoit, Moranvillier, Isabelle, Taillepierre, Miguel, Peuchant, Evelyne, Guyonnet-Dupérat, Véronique, Bedel, Aurélie, Dubus, Pierre, de Verneuil, Hubert, Moreau-Gaudry, François, Dabernat, Sandrine

“…Pancreatic ductal adenocarcinoma is a deadly malignancy resistant to current therapies. It is critical to test new strategies, including tumor-targeted…”
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Resveratrol and capsaicin used together as food complements reduce tumor growth and rescue full efficiency of low dose gemcitabine in a pancreatic cancer model by Vendrely, Véronique, Peuchant, Evelyne, Buscail, Etienne, Moranvillier, Isabelle, Rousseau, Benoit, Bedel, Aurélie, Brillac, Aurélia, de Verneuil, Hubert, Moreau-Gaudry, François, Dabernat, Sandrine

“…Abstract Pancreatic adenocarcinoma, highly resistant to all current anti-cancer treatments, necessitates new approaches promoting cell death. We hypothesized…”
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Targeted gene therapy in human-induced pluripotent stem cells from a patient with primary hyperoxaluria type 1 using CRISPR/Cas9 technology by Estève, Julie, Blouin, Jean-Marc, Lalanne, Magalie, Azzi-Martin, Lamia, Dubus, Pierre, Bidet, Audrey, Harambat, Jérôme, Llanas, Brigitte, Moranvillier, Isabelle, Bedel, Aurélie, Moreau-Gaudry, François, Richard, Emmanuel

“…Primary hyperoxaluria type 1 (PH1) is an inherited metabolic disorder caused by a deficiency of the peroxisomal enzyme alanine-glyoxylate aminotransferase…”
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Combination treatment of resveratrol and capsaicin radiosensitizes pancreatic tumor cells by unbalancing DNA repair response to radiotherapy towards cell death by Vendrely, Véronique, Amintas, Samuel, Noel, Cécile, Moranvillier, Isabelle, Lamrissi, Isabelle, Rousseau, Benoit, Coulibaly, Soulé, Bedel, Aurélie, Moreau-Gaudry, François, Buscail, Etienne, Chiche, Laurence, Belleannée, Geneviève, Dupin, Charles, Dabernat, Sandrine

“…Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers because it is highly resistant to every available therapeutic strategy, in…”
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CRISPR editing to mimic porphyria combined with light: A new preclinical approach for prostate cancer by Boutin, Julian, Genevois, Coralie, Couillaud, Franck, Lamrissi-Garcia, Isabelle, Guyonnet-Duperat, Veronique, Bibeyran, Alice, Lalanne, Magalie, Amintas, Samuel, Moranvillier, Isabelle, Richard, Emmanuel, Blouin, Jean-Marc, Dabernat, Sandrine, Moreau-Gaudry, François, Bedel, Aurélie

“…Thanks to its very high genome-editing efficiency, CRISPR-Cas9 technology could be a promising anticancer weapon. Clinical trials using CRISPR-Cas9 nuclease to…”
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Mutation-Specific Guide RNA for Compound Heterozygous Porphyria On-target Scarless Correction by CRISPR/Cas9 in Stem Cells by Prat, Florence, Toutain, Jérôme, Boutin, Julian, Amintas, Samuel, Cullot, Grégoire, Lalanne, Magalie, Lamrissi-Garcia, Isabelle, Moranvillier, Isabelle, Richard, Emmanuel, Blouin, Jean-Marc, Dabernat, Sandrine, Moreau-Gaudry, François, Bedel, Aurélie

“…CRISPR/Cas9 is a promising technology for gene correction. However, the edition is often biallelic, and uncontrolled small insertions and deletions (indels)…”
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FGFR3 has tumor suppressor properties in cells with epithelial phenotype by Lafitte, Marie, Moranvillier, Isabelle, Garcia, Stéphane, Peuchant, Evelyne, Iovanna, Juan, Rousseau, Benoit, Dubus, Pierre, Guyonnet-Dupérat, Véronique, Belleannée, Geneviève, Ramos, Jeanne, Bedel, Aurélie, de Verneuil, Hubert, Moreau-Gaudry, François, Dabernat, Sandrine

“…Due to frequent mutations in certain cancers, FGFR3 gene is considered as an oncogene. However, in some normal tissues, FGFR3 can limit cell growth and promote…”
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Are extracellular vesicles able to control human pluripotent stem cell fate? by Buscail, Etienne, Quincy, Pascaline, Gounou, Celine, Raymond, Anne-Aurelie, Lamrissi-Garcia, Isabelle, Moranvillier, Isabelle, Saltel, Frederic, Moreau-Gaudry, François, Chiche, Laurence, Bedel, Aurelie, Brisson, Alain, Dabernat, Sandrine

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Preventing Pluripotent Cell Teratoma in Regenerative Medicine Applied to Hematology Disorders by Bedel, Aurelie, Beliveau, François, Lamrissi-Garcia, Isabelle, Rousseau, Benoit, Moranvillier, Isabelle, Rucheton, Benoit, Guyonnet-Dupérat, Veronique, Cardinaud, Bruno, de Verneuil, Hubert, Moreau-Gaudry, François, Dabernat, Sandrine

“…: Iatrogenic tumorigenesis is a major limitation for the use of human induced pluripotent stem cells (hiPSCs) in hematology. The teratoma risk comes from the…”
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CD63-GPC1-Positive Exosomes Coupled with CA19-9 Offer Good Diagnostic Potential for Resectable Pancreatic Ductal Adenocarcinoma by Buscail, Etienne, Chauvet, Alexandre, Quincy, Pascaline, Degrandi, Olivier, Buscail, Camille, Lamrissi, Isabelle, Moranvillier, Isabelle, Caumont, Charline, Verdon, Severine, Brisson, Alain, Marty, Marion, Chiche, Laurence, Laurent, Christophe, Vendrely, Veronique, Moreau-Gaudry, Francois, Bedel, Aurelie, Dabernat, Sandrine

“…Tumor-released extracellular vesicles (EVs) contain tumor-specific cargo distinguishing them from healthy EVs, and making them eligible as circulating…”
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Acute oxidative stress is associated with cell proliferation in the mouse liver by Dragin, Nadine, Smani, Moneïm, Arnaud-Dabernat, Sandrine, Dubost, Clément, Moranvillier, Isabelle, Costet, Pierre, Daniel, Jean-Yves, Peuchant, Evelyne

“…Oxidative stress is known to produce tissue injury and to activate various signaling pathways. To investigate the molecular events linked to acute oxidative…”
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