Search Results - "Morani, Gabriele"
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Acid sensing ion channel 2: A new potential player in the pathophysiology of multiple sclerosis
Published in The European journal of neuroscience (01-05-2019)“…Acid‐sensing ion channels (ASICs) are proton‐gated channels involved in multiple biological functions such as: pain modulation, mechanosensation,…”
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Genetic Determinants of Lipids and Cardiovascular Disease Outcomes: A Wide-Angled Mendelian Randomization Investigation
Published in Circulation. Genomic and precision medicine (01-12-2019)“…Evidence from randomized trials has shown that therapies that lower LDL (low-density lipoprotein)-cholesterol and triglycerides reduce coronary artery disease…”
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Abstract PD15-02: HER2-enriched subtype and novel molecular subgroups drive aromatase inhibitor resistance and an increased risk of relapse in early ER+/HER2+ breast cancer
Published in Cancer research (Chicago, Ill.) (15-02-2022)“…Background: Approximately 10% of estrogen receptor positive (ER+) early breast cancers (EBC) are human epidermal growth factor positive/overexpressed (HER2+)…”
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Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor-positive Breast Cancers
Published in Clinical cancer research (15-03-2022)“…Aromatase inhibitor (AI) treatment is the standard of care for postmenopausal women with primary estrogen receptor-positive breast cancer. The impact of…”
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Proteomic profiling of soft tissue sarcomas with SWATH mass spectrometry
Published in Journal of proteomics (15-06-2021)“…Soft tissue sarcomas (STS) are a group of rare and heterogeneous cancers. While large-scale genomic and epigenomic profiling of STS have been undertaken,…”
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Abstract P2-03-07: Multi-parametric algorithm integrating on-treatment Ki67 value and standard clinicopathological variables to predict risk of recurrences for women > 70 years old with early ER+HER2- tumours in POETIC trial
Published in Cancer research (Chicago, Ill.) (01-03-2023)“…Background: Prognosis in older patients with breast cancer (BC) is worse compared to younger patients. No robust and specific tool to predict the risk of…”
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