Search Results - "Morande, Pablo Elías"
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Diagnostic and Therapeutic Potential of Extracellular Vesicles in B-Cell Malignancies
Published in Frontiers in oncology (29-09-2020)“…Extracellular vesicles (EV), comprising microvesicles and exosomes, are particles released by every cell of an organism, found in all biological fluids, and…”
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Ibrutinib therapy downregulates AID enzyme and proliferative fractions in chronic lymphocytic leukemia
Published in Blood (09-05-2019)“…Activation-induced cytidine deaminase (AID) initiates somatic hypermutation and class switch recombination of the immunoglobulin genes. As a trade-off for its…”
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The protective role of the microenvironment in hairy cell leukemia treatment: Facts and perspectives
Published in Frontiers in oncology (08-03-2023)“…Hairy cell leukemia (HCL) is an incurable, rare lymphoproliferative hematological malignancy of mature B cAlthough first line therapy with purine analogues…”
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In Vitro Sensitivity to Venetoclax and Microenvironment Protection in Hairy Cell Leukemia
Published in Frontiers in oncology (26-07-2021)“…Current standard treatment of patients with hairy cell leukemia (HCL), a chronic B-cell neoplasia of low incidence that affects the elderly, is based on the…”
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CXCL12-induced chemotaxis is impaired in T cells from patients with ZAP-70-negative chronic lymphocytic leukemia
Published in Haematologica (Roma) (01-05-2010)“…T cells from patients with chronic lymphocytic leukemia may play an important role in contributing to the onset, sustenance, and exacerbation of the disease by…”
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AID overexpression leads to aggressive murine CLL and nonimmunoglobulin mutations that mirror human neoplasms
Published in Blood (22-07-2021)“…Most cancers become more dangerous by the outgrowth of malignant subclones with additional DNA mutations that favor proliferation or survival. Using chronic…”
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Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses
Published in Blood cancer discovery (06-01-2023)“…Small extracellular vesicle (sEV, or exosome) communication among cells in the tumor microenvironment has been modeled mainly in cell culture, whereas their…”
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CXCL12 is a costimulator for CD4+ T cell activation and proliferation in chronic lymphocytic leukemia patients
Published in Cancer Immunology, Immunotherapy (01-01-2013)“…Activated T cells from patients with chronic lymphocytic leukemia (CLL) provide survival and proliferative signals to the leukemic clone within lymphoid…”
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CCR4 expression in a case of cutaneous Richter’s transformation of chronic lymphocytic leukemia (CLL) to diffuse large B‐cell lymphoma (DLBCL) and in CLL patients with no skin manifestations
Published in European journal of haematology (01-07-2011)“…Objective: Richter’s transformation of B‐cell chronic lymphocytic leukemia (CLL) to cutaneous diffuse large B‐cell lymphoma (DLBCL) is very rare. We took the…”
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Protocol for isolating leukemia-derived extracellular vesicles from the spleen of preclinical models of leukemia using ultracentrifugation
Published in STAR protocols (20-09-2024)“…Here, we present a protocol for the direct isolation of small extracellular vesicles (sEVs) from the spleen of preclinical murine models of leukemia using…”
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AID overexpression leads to aggressive murine CLL and non-Ig mutations that mirror human neoplasms
Published in Blood (02-03-2021)“…Most cancers become more dangerous by the outgrowth of malignant subclones with additional DNA mutations that favor proliferation or survival. Using chronic…”
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CXCL12 is a costimulator for CD4^sup +^ T cell activation and proliferation in chronic lymphocytic leukemia patients
Published in Cancer immunology, immunotherapy (01-01-2013)“…Activated T cells from patients with chronic lymphocytic leukemia (CLL) provide survival and proliferative signals to the leukemic clone within lymphoid…”
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CCR4 expression in a case of cutaneous Richter’s transformation of chronic lymphocytic leukemia (CLL) to diffuse large B-cell lymphoma (DLBCL) and in CLL patients with no skin manifestations: CCR4 in a case of DLBCL transformation
Published in European journal of haematology (01-07-2011)Get full text
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2.8 CXCL12 Is a Costimulator for CD4+ T-Cell Activation and Proliferation in Patients with Chronic Lymphocytic Leukemia
Published in Clinical lymphoma, myeloma and leukemia (01-10-2011)Get full text
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CXCL12 is a costimulator for CD4 super(+) T cell activation and proliferation in chronic lymphocytic leukemia patients
Published in Cancer Immunology, Immunotherapy (01-01-2013)“…Activated T cells from patients with chronic lymphocytic leukemia (CLL) provide survival and proliferative signals to the leukemic clone within lymphoid…”
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