Search Results - "Moran, TM"

In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination by Bonifaz, Laura C, Bonnyay, David P, Charalambous, Anna, Darguste, Dara I, Fujii, Shin-Ichiro, Soares, Helena, Brimnes, Marie K, Moltedo, Bruno, Moran, Thomas M, Steinman, Ralph M

“…The prevention and treatment of prevalent infectious diseases and tumors should benefit from improvements in the induction of antigen-specific T cell immunity…”
Get full text

Dendritic Cell-Specific Intercellular Adhesion Molecule 3-Grabbing Nonintegrin/CD209 Is Abundant on Macrophages in the Normal Human Lymph Node and Is Not Required for Dendritic Cell Stimulation of the Mixed Leukocyte Reaction by Granelli-Piperno, Angela, Pritsker, Alla, Pack, Maggi, Shimeliovich, Irina, Arrighi, Jean-Francois, Park, Chae Gyu, Trumpfheller, Christine, Piguet, Vincent, Moran, Thomas M, Steinman, Ralph M

“…The C-type lectin dendritic cell-specific ICAM 3-grabbing nonintegrin (DC-SIGN)/CD209 efficiently binds several pathogens, including HIV-1. DC-SIGN is…”
Get full text

Intensified and protective CD4+ T cell immunity in mice with anti-dendritic cell HIV gag fusion antibody vaccine by Trumpfheller, Christine, Finke, Jennifer S, López, Carolina B, Moran, Thomas M, Moltedo, Bruno, Soares, Helena, Huang, Yaoxing, Schlesinger, Sarah J, Park, Chae Gyu, Nussenzweig, Michel C, Granelli-Piperno, Angela, Steinman, Ralph M

“…Current human immunodeficiency virus (HIV) vaccine approaches emphasize prime boost strategies comprising multiple doses of DNA vaccine and recombinant viral…”
Get full text

TLR-Independent Induction of Dendritic Cell Maturation and Adaptive Immunity by Negative-Strand RNA Viruses by Lopez, Carolina B, Moltedo, Bruno, Alexopoulou, Lena, Bonifaz, Laura, Flavell, Richard A, Moran, Thomas M

“…TLR signaling leads to dendritic cell (DC) maturation and immunity to diverse pathogens. The stimulation of TLRs by conserved viral structures is the only…”
Get full text

Influenza virus-induced dendritic cell maturation is associated with the induction of strong T cell immunity to a coadministered, normally nonimmunogenic protein by Brimnes, Marie K, Bonifaz, Laura, Steinman, Ralph M, Moran, Thomas M

“…We evaluated the proposal that during microbial infection, dendritic cells (DCs) undergo maturation and present a mixture of peptides derived from the microbe…”
Get full text

Induction of mucosal tolerance in Peyer's patch-deficient, ligated small bowel loops by Kraus, Thomas A, Brimnes, Jens, Muong, Christine, Liu, Jian-Hua, Moran, Thomas M, Tappenden, Kelly A, Boros, Peter, Mayer, Lloyd

“…To explore the requirement for M cells and the Peyer's patch (PP) in induction of oral tolerance and address the potential in vivo role of intestinal…”
Get full text

The C-Type Lectin SIGN-R1 Mediates Uptake of the Capsular Polysaccharide of Streptococcus pneumoniae in the Marginal Zone of Mouse Spleen by Kang, Young-Sun, Kim, Jae Y., Bruening, Sandra A., Pack, Maggi, Charalambous, Anna, Pritsker, Alla, Moran, Thomas M., Loeffler, Jutta M., Steinman, Ralph M., Park, Chae Gyu

“…SIGN-R1, a recently discovered C-type lectin expressed at high levels on macrophages within the marginal zone of the spleen, mediates the uptake of dextran…”
Get full text

Type I Interferon Induction Pathway, but Not Released Interferon, Participates in the Maturation of Dendritic Cells Induced by Negative-Strand RNA Viruses by López, Carolina B, García-Sastre, Adolfo, Williams, Bryan R. G, Moran, Thomas M

“…Signaling through toll-like receptors (TLRs) is essential for dendritic cell (DC) maturation induced by bacteria and other pathogens. The mechanism for…”
Get full text

Toll-like receptor-independent triggering of dendritic cell maturation by viruses by LOPEZ, Carolina B, YOUNT, Jacob S, MORAN, Thomas M

Get full text

Sendai Virus Infection Induces Efficient Adaptive Immunity Independently of Type I Interferons by LOPEZ, Carolina B, YOUNT, Jacob S, HERMESH, Tamar, MORAN, Thomas M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Th2 Responses to Inactivated Influenza Virus Can Be Converted to Th1 Responses and Facilitate Recovery from Heterosubtypic Virus Infection by Moran, Thomas M., Park, Helen, Fernandez-Sesma, Ana, Schulman, Jerome L.

“…Immunization with live influenza virus expands Th1 memory cells and facilitates more rapid recovery after heterosubtypic virus challenge. Immunization with…”
Get full text

Attenuation and immunogenicity in mice of temperature-sensitive influenza viruses expressing truncated NS1 proteins by Falcon, Ana M, Fernandez-Sesma, Ana, Nakaya, Yurie, Moran, Thomas M, Ortin, Juan, Garcia-Sastre, Adolfo

“…1 Centro Nacional de Biotecnología, CSIC, 28049 Madrid, Spain 2 Department of Microbiology, Mount Sinai School of Medicine, Box 1124, 1 Gustave L. Levy Place,…”
Get full text

Reepithelialized orthotopic tracheal allografts expand memory cytotoxic T lymphocytes but show no evidence of chronic rejection by CLEVEN, Heidi A, GENDEN, Eric M, MORAN, Thomas M

“…Acute rejection of mouse tracheal allografts is characterized by infiltration of the lamina propria with CD4+/CD8+ T cells that leads to the destruction of the…”
Get full text

Interleukin-4 causes delayed virus clearance in influenza virus-infected mice by Moran, T M, Isobe, H, Fernandez-Sesma, A, Schulman, J L

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Glutamate receptor subunit 3 (GluR3) immunoreactivity delineates a subpopulation of parvalbumin-containing interneurons in the rat hippocampus by Moga, Diana E., Janssen, William G.M., Vissavajjhala, Prabhakar, Czelusniak, Sharon M., Moran, Thomas M., Hof, Patrick R., Morrison, John H.

“…Rasmussen's encephalitis is a childhood disease resulting in intractable seizures associated with hippocampal and neocortical inflammation. An autoantibody…”
Get full text

A Mouse Model for Immunization with Ex Vivo Virus-Infected Dendritic Cells by López, Carolina B., Fernandez-Sesma, Ana, Czelusniak, Sharon M., Schulman, Jerome L., Moran, Thomas M.

“…Dendritic cells (DCs) have been demonstrated to be an important if not essential inducer of cellular immune responses. The ability to grow these cells in vitro…”
Get full text

Parvalbumin-containing interneurons in rat hippocampus have an AMPA receptor profile suggestive of vulnerability to excitotoxicity by Moga, Diana, Hof, Patrick R., Vissavajjhala, Prabhakar, Moran, Thomas M., Morrison, John H.

“…α-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors mediate excitatory neurotransmission in the central nervous system, and contain…”
Get full text

Myeloid dendritic cells stimulate both Th1 and Th2 immune responses depending on the nature of the antigen by López, C B, Fernandez-Sesma, A, Schulman, J L, Moran, T M

“…It has been shown that different types of pathogens induce different immune responses. Recovery from intracellular bacterial and viral infection is dependent…”
Get more information

Antigen-Presenting B Cells and Helper T Cells Cooperatively Mediate Intravirionic Antigenic Competition between Influenza A Virus Surface Glycoproteins by Johansson, Bert E., Moran, Thomas M., Kilbourne, Edwin D.

“…Parenteral vaccination of BALB/c mice primed by infection with H3N2 variants of influenza A virus results in a reduced production of N2 antibody in response to…”
Get full text

A bispecific antibody recognizing influenza A virus M2 protein redirects effector cells to inhibit virus replication in vitro by Fernandez-Sesma, A, Schulman, J L, Moran, T M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text