Search Results - "Moran, N"
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Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution
Published in Genome Biology (29-01-2015)“…Long non-coding RNAs (lncRNAs) have been implicated in diverse biological processes. In contrast to extensive genomic annotation of lncRNA transcripts, far…”
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Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses
Published in Genes & development (15-09-2011)“…Large intergenic noncoding RNAs (lincRNAs) are emerging as key regulators of diverse cellular processes. Determining the function of individual lincRNAs…”
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Peptidomic discovery of short open reading frame–encoded peptides in human cells
Published in Nature chemical biology (01-01-2013)“…The human genome contains stretches of DNA sequence with unknown function. Peptidomics coupled to RNA-Seq now reveals a class of short open reading frames in…”
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Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells
Published in Nature genetics (01-12-2010)“…The conversion of lineage-committed cells to induced pluripotent stem cells (iPSCs) by reprogramming is accompanied by a global remodeling of the epigenome,…”
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Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
Published in Nature (12-03-2009)“…There is growing recognition that mammalian cells produce many thousands of large intergenic transcripts. However, the functional significance of these…”
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Visualization of lncRNA by single-molecule fluorescence in situ hybridization
Published in Methods in molecular biology (Clifton, N.J.) (2015)“…Single-molecule RNA fluorescence in situ hybridization is a technique that holds great potential for the study of long noncoding RNA. It enables quantification…”
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Predicting metabolic biomarkers of human inborn errors of metabolism
Published in Molecular systems biology (2009)“…Early diagnosis of inborn errors of metabolism is commonly performed through biofluid metabolomics, which detects specific metabolic biomarkers whose…”
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Implementing E-MOTIVE for detection and treatment of postpartum haemorrhage in South Africa
Published in South African medical journal (01-12-2023)“…Postpartum haemorrhage is the leading cause of preventable maternal mortality in South Africa. In a significant breakthrough in the management of PPH, the…”
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linc-HOXA1 is a noncoding RNA that represses Hoxa1 transcription in cis
Published in Genes & development (01-06-2013)“…Recently, researchers have uncovered the presence of many long noncoding RNAs (lncRNAs) in embryonic stem cells and believe they are important regulators of…”
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Visualization methods for differential expression analysis
Published in BMC bioinformatics (06-09-2019)“…Despite the availability of many ready-made testing software, reliable detection of differentially expressed genes in RNA-seq data is not a trivial task. Even…”
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The Daily Mile makes primary school children more active, less sedentary and improves their fitness and body composition: a quasi-experimental pilot study
Published in BMC medicine (10-05-2018)“…The Daily Mile is a physical activity programme made popular by a school in Stirling, Scotland. It is promoted by the Scottish Government and is growing in…”
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High‐throughput identification of RNA nuclear enrichment sequences
Published in The EMBO journal (15-03-2018)“…In the post‐genomic era, thousands of putative noncoding regulatory regions have been identified, such as enhancers, promoters, long noncoding RNAs (lncRNAs),…”
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The maize Ga1-s allele confers protection against ga1 pollen in popcorn and dent corn
Published in Scientific reports (02-12-2022)“…Because corn pollen can be carried great distances by wind, maintaining genetic purity of corn grain is challenging. The challenge is substantially reduced in…”
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Network-based prediction of human tissue-specific metabolism
Published in Nature biotechnology (01-09-2008)“…Metabolic network modeling in multicellular organisms is confounded by the existence of multiple tissues with distinct metabolic functions. By integrating a…”
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Predicting EGFR mutational status from pathology images using a real-world dataset
Published in Scientific reports (16-03-2023)“…Treatment of non-small cell lung cancer is increasingly biomarker driven with multiple genomic alterations, including those in the epidermal growth factor…”
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A citizen science study of short physical activity breaks at school: improvements in cognition and wellbeing with self-paced activity
Published in BMC medicine (17-03-2020)“…School-based physical activity and running programmes, such as The Daily Mile™, are increasing in popularity globally. The aim of this research was to examine…”
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The Daily Mile: What factors are associated with its implementation success?
Published in PloS one (04-10-2018)“…Despite the known benefits of a physically active lifestyle, there are few examples of interventions that have been successfully implemented at a population…”
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Plasma microRNA levels differ between endurance and strength athletes
Published in PloS one (16-04-2015)“…MicroRNAs (miRNAs) are stable in the circulation and are likely to function in inter-organ communication during a variety of metabolic responses that involve…”
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Grit, Athlete Burnout, and Well-Being in Female Collegiate Student-Athletes
Published in Journal of athletic training (01-10-2023)“…Collegiate student-athletes are faced with significant athletic and academic demands, causing a substantial amount of stress, which can lead to athlete…”
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Dynamics and level statistics of interacting fermions in the lowest Landau level
Published in New journal of physics (26-10-2018)“…We consider the unitary dynamics of interacting fermions in the lowest Landau level, on spherical and toroidal geometries. The dynamics are driven by the…”
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