Search Results - "Moran, Justin"

Antitumor Efficacy of a Combination of CMC-544 (Inotuzumab Ozogamicin), a CD22-Targeted Cytotoxic Immunoconjugate of Calicheamicin, and Rituximab against Non-Hodgkin's B-Cell Lymphoma by DIJOSEPH, John F, DOUGHER, Maureen M, KALYANDRUG, Lyka B, ARMELLINO, Douglas C, BOGHAERT, Erwin R, HAMANN, Philip R, MORAN, Justin K, DAMLE, Nitin K

“…Purpose: CMC-544 is a CD22-targeted cytotoxic immunoconjugate, currently being evaluated in B-cell non-Hodgkin's lymphoma (B-NHL) patients. Rituximab is a…”
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Antibody-targeted chemotherapy with CMC-544: a CD22-targeted immunoconjugate of calicheamicin for the treatment of B-lymphoid malignancies by DiJoseph, John F., Armellino, Douglas C., Boghaert, Erwin R., Khandke, Kiran, Dougher, Maureen M., Sridharan, Latha, Kunz, Arthur, Hamann, Philip R., Gorovits, Boris, Udata, Chandrasekhar, Moran, Justin K., Popplewell, Andrew G., Stephens, Sue, Frost, Philip, Damle, Nitin K.

“…Antibody-targeted chemotherapy with gemtuzumab ozogamicin (CMA-676, a CD33-targeted immunoconjugate of N-acetyl-γ-calicheamicin dimethyl hydrazide [CalichDMH],…”
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Optimization of Urinary FDG Excretion During PET Imaging by Moran, Justin K, Lee, Hyo B, Blaufox, M. Donald

“…Accumulation of fluorodeoxyglucose (FDG) activity in the urine interferes with the visualization of pelvic and, sometimes, abdominal abnormalities. Although…”
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Synthesis of the Protein Cutting Reagent Iron (S)-1-(p-Bromoacetamidobenzyl)ethylenediaminetetraacetate and Conjugation to Cysteine Side Chains by Greiner, Douglas P, Miyake, Reiko, Moran, Justin K, Jones, A. Daniel, Negishi, Tomofumi, Ishihama, Akira, Meares, Claude F

“…Convenient methodology for preparation and conjugation of the protein-cutting iron chelate iron (S)-1-(p-bromoacetamidobenzyl)ethylenediaminetetraacetate…”
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Horizontal Transmission of Cytomegalovirus in a Rhesus Model Despite High-Level, Vaccine-Elicited Neutralizing Antibody and T-Cell Responses by Li, Julia, Wellnitz, Sabine, Chi, Xiaoyuan S, Yue, Yujuan, Schmidt, Kimberli A, Nguyen, Nancy, Chen, Wei, Yurgelonis, Irina, Rojas, Eduardo, Liu, Yuhang, Loschko, Jakob, Pollozi, Eneida, Matsuka, Yury V, Needle, Elie, Vidunas, Eugene, Donald, Robert G K, Moran, Justin, Jansen, Kathrin U, Dormitzer, Philip R, Barry, Peter A, Yang, Xinzhen

“…Abstract The development of a vaccine to prevent congenital human cytomegalovirus (HCMV) disease is a public health priority. We tested rhesus CMV (RhCMV)…”
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Identification of a Novel Keto Sugar Component in Streptococcus pneumoniae Serotype 12F Capsular Polysaccharide and Impact on Vaccine Immunogenicity by Sackett, Kelly, Brown, Paul, Dutta, Kaushik, Scully, Ingrid L, Gangolli, Seema, Looi, Kelvin, Nemani, Sandeep, Yu, Angela Yeou Hsiung, Kleven, Mark, Xie, Jin, Moran, Justin, Pride, Michael W, Anderson, Annaliesa S, Lotvin, Jason

“…Implementation of conjugate vaccine technology revolutionized the ability to effectively elicit long-lasting immune responses to bacterial capsular…”
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Accelerated regression of brain metastases in patients receiving whole brain radiation and the topoisomerase II inhibitor, lucanthone by Del Rowe, J D, Bello, J, Mitnick, R, Sood, B, Filippi, C, Moran, J, Freeman, K, Mendez, F, Bases, R

“…To determine if lucanthone crossed the blood-brain barrier in experimental animals; and to determine accelerated tumor regression of human brain metastases…”
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Introduction of diphenylphosphinite functional groups onto selected positions on the lower rim of calix[4]arenes and calix[6]arenes by Moran, Justin K, Roundhill, D. Max

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Three-Dimensional Structure and Biophysical Characterization of Staphylococcus aureus Cell Surface Antigen–Manganese Transporter MntC by Gribenko, Alexey, Mosyak, Lidia, Ghosh, Sharmistha, Parris, Kevin, Svenson, Kristine, Moran, Justin, Chu, Ling, Li, Sheng, Liu, Tong, Woods, Virgil L., Jansen, Kathrin U., Green, Bruce A., Anderson, Annaliesa S., Matsuka, Yury V.

“…MntC is a metal-binding protein component of the Mn2+-specific mntABC transporter from the pathogen Staphylococcus aureus. The protein is expressed during the…”
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Production and Characterization of Chemically Inactivated Genetically Engineered Clostridium difficile Toxoids by Vidunas, Eugene, Mathews, Antony, Weaver, Michele, Cai, Ping, Koh, Eun Hee, Patel-Brown, Sujata, Yuan, Hailey, Zheng, Zi-Rong, Carriere, Marjolaine, Johnson, J Erik, Lotvin, Jason, Moran, Justin

“…A recombinant Clostridium difficile expression system was used to produce genetically engineered toxoids A and B as immunogens for a prophylactic vaccine…”
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Synthesis and Structural Characterization of Calix[4]arenes, Calix[6]arenes, and Calix[8]arenes with 3-Hydroxypropoxy or 2-Hydroxyethoxy Functional Groups Appended onto the Lower Rim by Moran, Justin K, Georgiev, Emil M, Yordanov, Alex T, Mague, Joel T, Roundhill, D. Max

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Improved Synthesis of 6-[p-(Bromoacetamido)benzyl]- 1,4,8,11-tetraazacyclotetradecane-N,N',N'',N'''-tetraacetic Acid and Development of a Thin-Layer Assay for Thiol-Reactive Bifunctional Chelating Agents by Moran, Justin K, Greiner, Douglas P, Meares, Claude F

“…Monoclonal antibodies labeled with radiometals such as copper-67 have applications in radioimmunodiagnosis and radioimmunotherapy. Moi et al. [(1985) Anal…”
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NMR structural analysis of the capsular polysaccharide from Streptococcus pneumoniae serotype 6C by Cai, Ping, Moran, Justin, Pavliak, Viliam, Deng, Chenghua, Khoury, Nancy, Marcq, Olivier, Ruppen, Mark E

“…The original structure of Streptococcus pneumoniae capsular polysaccharide (CPS) serotype 6C was proposed based on chemical degradation and tandem mass…”
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Determination of pharmacokinetic values of calicheamicin-antibody conjugates in mice by plasmon resonance analysis of small (5 μl) blood samples by Boghaert, Erwin R., Khandke, Kiran M., Sridharan, Latha, Dougher, Maureen, DiJoseph, John F., Kunz, Arthur, Hamann, Philip R., Moran, Justin, Chaudhary, Inder, Damle, Nitin K.

“…Purpose The present study aims to establish a method that provides fast, precise and reproducible pharmacokinetic (PK) parameters of antibody-calicheamicin…”
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NMR structural analysis of the capsular polysaccharide from Streptococcuspneumoniae serotype 6C by Cai, Ping, Moran, Justin, Pavliak, Viliam, Deng, Chenghua, Khoury, Nancy, Marcq, Olivier, Ruppen, Mark E.

“…[Display omitted] ► The repeat unit structure of serotype 6C is established by various NMR spectra study. ► 2D-NMR studies led to full 1H and 13C NMR spectra…”
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Technetium-99m-EC and other potential new agents in renal nuclear medicine by Moran, Justin K.

“…Search for the ideal radiopharmaceutical to measure effective renal plasma flow (ERPF) has been underway since the early 1960s. Although ortho-iodohippuran…”
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New approaches to delivering metal-labeled antibodies to tumors: Synthesis and characterization of new biotinyl chelate conjugates for pre-targeted diagnosis and therapy by Renn, Oliver, Goodwin, David A., Studer, Martin, Moran, Justin K., Jacques, Vincent, Meares, Claude F.

“…Radiolabeled monoclonal antibodies are widely used in the detection and treatment of cancer. However, several problems still prevent full clinical exploitation…”
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Synthesis of modified calixarenes for imaging applications by Moran, Justin Keith

“…The recent increase of interest in metals used in medical imaging procedures, led to the investigation of calixarenes as possible ligands for imaging…”
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Dirhenium complexes containing pairs of bridging acetate and bis(diphenylphosphino)amine ligands. Cis and trans isomers of the type [Re2(O2CCH3)2X2(Ph2PNHPPh2)2]n+ (X = Cl, Br: n = p, 1) by Derringer, Daniel R, Fanwick, Phillip E, Moran, Justin, Walton, Richard A

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