Search Results - "Moran, Ellen"

Abacavir-reactive memory T cells are present in drug naïve individuals by Lucas, Andrew, Lucas, Michaela, Strhyn, Anette, Keane, Niamh M, McKinnon, Elizabeth, Pavlos, Rebecca, Moran, Ellen M, Meyer-Pannwitt, Viola, Gaudieri, Silvana, D'Orsogna, Lloyd, Kalams, Spyros, Ostrov, David A, Buus, Søren, Peters, Bjoern, Mallal, Simon, Phillips, Elizabeth

“…Fifty-five percent of individuals with HLA-B*57:01 exposed to the antiretroviral drug abacavir develop a hypersensitivity reaction (HSR) that has been…”
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Demodex and Rosacea Revisited by Moran, Ellen M., B.A (Mod), PhD, Foley, Ruth, B.A (Mod), PhD, Powell, Frank C, FRCPI, FRCPEdin

“…Abstract Demodex mites are part of the vast microbiome living on and within human skin. The interaction of the various microorganisms with the skin plays a key…”
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Airborne Particulate Concentrations During and After Pulmonary Function Testing by Li, Jie, Jing, Guoqiang, Fink, James B., Porszasz, Janos, Moran, Ellen M., Kiourkas, Renee D., McLaughlin, Roisin, Vines, David L., Dhand, Rajiv

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Biochemical characterization of two novel mutations in the human high-affinity choline transporter 1 identified in a patient with congenital myasthenic syndrome by Rizvi, Midhat, Truong, Tina K, Zhou, Janet, Batta, Manav, Moran, Ellen S, Pappas, John, Chu, Mary Lynn, Caluseriu, Oana, Evrony, Gilad D, Leslie, Elaine M, Cordat, Emmanuelle

“…Abstract Congenital myasthenic syndrome (CMS) is a heterogeneous condition associated with 34 different genes, including SLC5A7, which encodes the…”
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Human rheumatoid arthritis tissue production of IL-17A drives matrix and cartilage degradation: synergy with tumour necrosis factor-alpha, Oncostatin M and response to biologic therapies by Moran, Ellen M, Mullan, Ronan, McCormick, Jennifer, Connolly, Mary, Sullivan, Owen, Fitzgerald, Oliver, Bresnihan, Barry, Veale, Douglas J, Fearon, Ursula

“…The aim of this study was to examine IL-17A in patients, following anti-TNF-alpha therapy and the effect of IL-17A on matrix turnover and cartilage…”
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DLCO Biologic Quality-Control Findings From a Multi-Center Global Study by Becker, Ellen A, Moran, Ellen M, Blonshine, Jason B, Blonshine, Susan B

“…The 2017 American Thoracic Society/European Respiratory Society (ATS/ERS) diffusing capacity of the lung for carbon monoxide (DLCO) standards specify a control…”
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De Novo Variants in the ATPase Module of MORC2 Cause a Neurodevelopmental Disorder with Growth Retardation and Variable Craniofacial Dysmorphism by Guillen Sacoto, Maria J., Tchasovnikarova, Iva A., Torti, Erin, Forster, Cara, Andrew, E. Hallie, Anselm, Irina, Baranano, Kristin W., Briere, Lauren C., Cohen, Julie S., Craigen, William J., Cytrynbaum, Cheryl, Ekhilevitch, Nina, Elrick, Matthew J., Fatemi, Ali, Fraser, Jamie L., Gallagher, Renata C., Guerin, Andrea, Haynes, Devon, High, Frances A., Inglese, Cara N., Kiss, Courtney, Koenig, Mary Kay, Krier, Joel, Lindstrom, Kristin, Marble, Michael, Meddaugh, Hannah, Moran, Ellen S., Morel, Chantal F., Mu, Weiyi, Muller, Eric A., Nance, Jessica, Natowicz, Marvin R., Numis, Adam L., Ostrem, Bridget, Pappas, John, Stafstrom, Carl E., Streff, Haley, Sweetser, David A., Szybowska, Marta, Walker, Melissa A., Wang, Wei, Weiss, Karin, Weksberg, Rosanna, Wheeler, Patricia G., Yoon, Grace, Kingston, Robert E., Juusola, Jane

“…MORC2 encodes an ATPase that plays a role in chromatin remodeling, DNA repair, and transcriptional regulation. Heterozygous variants in MORC2 have been…”
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IRAK-2 Participates in Multiple Toll-like Receptor Signaling Pathways to NFκB via Activation of TRAF6 Ubiquitination by Keating, Sinead E., Maloney, Geraldine M., Moran, Ellen M., Bowie, Andrew G.

“…Toll-like receptor (TLR) signaling is known to involve interleukin-1 receptor-associated kinases (IRAKs), however the particular role of IRAK-2 has remained…”
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IL-17A expression is localised to both mononuclear and polymorphonuclear synovial cell infiltrates by Moran, Ellen M, Heydrich, René, Ng, Chin Teck, Saber, Tajvur P, McCormick, Jennifer, Sieper, Joachim, Appel, Heiner, Fearon, Ursula, Veale, Douglas J

“…This study examines the expression of IL-17A-secreting cells within the inflamed synovium and the relationship to in vivo joint hypoxia measurements. IL-17A…”
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Variations in FVC and FEV1 Biologic Quality Control Measures in a Global Multi-Center Clinical Trial by Becker, Ellen A, Blonshine, Jason M, Bialek, Katarzyna, Moran, Ellen M, Blonshine, Susan B

“…BACKGROUNDAlthough quality control standards are recommended to ensure accurate test results, the coefficient of variation for the FVC and FEV1 biologic…”
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The Landscape of Genomic Services for Inherited Retinal Degenerations (IRDs) Across Europe by Paudel, Nabin, Daly, Avril, Moran, Ellen Margaret, Stratieva, Petia

“…To map the existing genomic services available for patients with IRDs across Europe. A survey was conducted to 24 ophthalmic and/or genetic specialists across…”
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Interleukin‐17A induction of angiogenesis, cell migration, and cytoskeletal rearrangement by Moran, Ellen M., Connolly, Mary, Gao, Wei, McCormick, Jennifer, Fearon, Ursula, Veale, Douglas J.

“…Objective To examine the ability of interleukin‐17A (IL‐17A) to stimulate angiogenesis, cell migration, and cytoskeletal rearrangement. Methods The effect of…”
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A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects by Zhang, Jinglan, Lachance, Véronik, Schaffner, Adam, Li, Xianting, Fedick, Anastasia, Kaye, Lauren E, Liao, Jun, Rosenfeld, Jill, Yachelevich, Naomi, Chu, Mary-Lynn, Mitchell, Wendy G, Boles, Richard G, Moran, Ellen, Tokita, Mari, Gorman, Elizabeth, Bagley, Kaytee, Zhang, Wei, Xia, Fan, Leduc, Magalie, Yang, Yaping, Eng, Christine, Wong, Lee-Jun, Schiffmann, Raphael, Diaz, George A, Kornreich, Ruth, Thummel, Ryan, Wasserstein, Melissa, Yue, Zhenyu, Edelmann, Lisa

“…Genetic leukoencephalopathies (gLEs) are a group of heterogeneous disorders with white matter abnormalities affecting the central nervous system (CNS). The…”
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EIF3F-related neurodevelopmental disorder: refining the phenotypic and expanding the molecular spectrum by Hüffmeier, Ulrike, Kraus, Cornelia, Reuter, Miriam S, Uebe, Steffen, Abbott, Mary-Alice, Ahmed, Syed A, Rawson, Kristyn L, Barr, Eileen, Li, Hong, Bruel, Ange-Line, Faivre, Laurence, Tran Mau-Them, Frédéric, Botti, Christina, Brooks, Susan, Burns, Kaitlyn, Ward, D Isum, Dutra-Clarke, Marina, Martinez-Agosto, Julian A, Lee, Hane, Nelson, Stanley F, Zacher, Pia, Abou Jamra, Rami, Klöckner, Chiara, McGaughran, Julie, Kohlhase, Jürgen, Schuhmann, Sarah, Moran, Ellen, Pappas, John, Raas-Rothschild, Annick, Sacoto, Maria J Guillen, Henderson, Lindsay B, Palculict, Timothy Blake, Mullegama, Sureni V, Zghal Elloumi, Houda, Reich, Adi, Schrier Vergano, Samantha A, Wahl, Erica, Reis, André, Zweier, Christiane

“…An identical homozygous missense variant in EIF3F, identified through a large-scale genome-wide sequencing approach, was reported as causative in nine…”
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P217: Abnormalities of TBX1 result in broad overlapping features of 22q11.2 deletion syndrome by McDonald-McGinn, Donna, Giunta, Victoria, Crowley, T. Blaine, McGinn, Daniel, Rockart, Lydia, Green, Audrey, Emanuel, Beverly, Smith, Rosemarie, Moran, Ellen, Geremek, Maciej, Zackai, Elaine, Nowakowska, Beata

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Antiviral Drug Allergy by Milpied-Homsi, Brigitte, MD, Moran, Ellen M., PhD, Phillips, Elizabeth J., MD

“…Antiviral drugs used to treat HIV and hepatitis C are common causes of delayed drug hypersensitivities for which many of the more severe reactions have been…”
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The role of interleukin-17 in immune-mediated inflammatory myopathies and possible therapeutic implications by Moran, Ellen M, Mastaglia, Frank L

“…Abstract The idiopathic inflammatory myopathies are a heterogeneous group of autoimmune muscle disorders with distinct clinical and pathological features and…”
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Impulse Oscillometry (IOS) Provides Important Additional Information During Methacholine Challeng by Casey, Larry, MD, Moran, Ellen, RRT, Gunn, Jason, MD

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Effect of Growth Hormone Therapy on Severe Short Stature and Skeletal Deformities in a Patient with Combined Turner Syndrome and Langer Mesomelic Dysplasia by Shah, Bina C., Moran, Ellen S., Zinn, Andrew R., Pappas, John G.

“…Background: Homozygous mutation of the short stature homeobox-containing gene, SHOX, results in Langer mesomelic dysplasia (LMD). Our case presented with…”
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The Limb–Girdle Muscular Dystrophies: Is Treatment on the Horizon? by Chu, Mary Lynn, Moran, Ellen

“…There has been an ever-expanding list of the Limb–Girdle Muscular Dystrophies (LGMD). There are currently 8 subtypes of autosomal dominant (AD) and 26 subtypes…”
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