Search Results - "Morales, T I"

Insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) is closely associated with the chondrocyte nucleus in human articular cartilage by Hunziker, E.B., M.D, Kapfinger, E, Martin, J., Ph.D, Buckwalter, J., M.D, Morales, T.I., Ph.D

“…Summary Objective Insulin-like growth factor-I (IGF-I) is critically involved in the control of cartilage matrix metabolism. It is well known that IGF-binding…”
Get full text

Chondrocyte moves: clever strategies? by Morales, T.I., Ph.D

“…Summary Goals To review the literature on chondrocyte movements and to develop plausible hypothesis for further work. Design Chondrocyte movements are herein…”
Get full text

High molar ratios of tumor necrosis factor α (TNF α) soluble receptors I and II to the TNF ligand in human plasma from male veterans with comorbid posttraumatic stress disorder (PTSD) and mild traumatic brain injury (mTBI) by Morales, T.I., Stamper, C.E., Brenner, L.A.

“…Posttraumatic stress disorder (PTSD) and traumatic brain injury (TBI) are associated with chronic inflammation, as inferred from increased, but variable,…”
Get full text

Transforming growth factor beta regulates the metabolism of proteoglycans in bovine cartilage organ cultures by Morales, T I, Roberts, A B

“…The effect of transforming growth factor beta (TGF-beta) has been studied in a bovine articular cartilage organ culture. The peptide stimulates synthesis of…”
Get full text

The role of nitric oxide in proteoglycan turnover by bovine articular cartilage organ cultures by Stefanovic-Racic, M, Morales, TI, Taskiran, D, McIntyre, LA, Evans, CH

“…Monolayer cultures of articular chondrocytes synthesize large amounts of nitric oxide (NO) following exposure to IL-1. The latter has antianabolic and…”
Get full text

Interactions of Glutamate and Gamma Amino Butyric Acid with the insulin-like growth factor system in traumatic brain injury (TBI) and/or cardiovascular accidents (CVA or stroke): A systematic review by Morales, T.I., Stearns-Yoder, K.A., Hoffberg, A.S., Khan, T.K., Wortzel, H., Brenner, L.A.

“…The brain maintains homeostasis of neural excitation in part through the receptor-mediated signaling of Glutamate (Glu) and Gamma Amino Butyric Acid (GABA),…”
Get full text

Transforming growth factor-beta in calf articular cartilage organ cultures: synthesis and distribution by Morales, T I, Joyce, M E, Sobel, M E, Danielpour, D, Roberts, A B

“…Transforming growth factor beta 1 (TGF-beta 1) has been shown to play a prominent role in controlling proteoglycan synthesis and breakdown as measured…”
Get more information

Correlated metabolism of proteoglycans and hyaluronic acid in bovine cartilage organ cultures by Morales, T I, Hascall, V C

“…Proteoglycans exist in cartilage as complexes in which many proteoglycan molecules are bound to a central filament of hyaluronic acid. Many studies have…”
Get full text

Insulin-like growth factors maintain steady-state metabolism of proteoglycans in bovine articular cartilage explants by Luyten, F P, Hascall, V C, Nissley, S P, Morales, T I, Reddi, A H

“…The influences of insulin-like growth factor I (IGF-I) and insulin-like growth factor II (IGF-II) on biosynthesis and catabolism of proteoglycans (PG) in…”
Get more information

Motile chondrocytes from newborn calf: migration properties and synthesis of collagen II by Chang, C, Lauffenburger, D.A, Morales, T.I

“…Objective: To determine whether differentiated chondrocytes are motile. Design: Calf articular chondrocytes isolated from six animals were cultured in spinner…”
Get full text

The effect of bacterial lipopolysaccharides on the biosynthesis and release of proteoglycans from calf articular cartilage cultures by Morales, T I, Wahl, L M, Hascall, V C

“…Organ cultures of bovine articular cartilage from metacarpophalangeal joints of calf maintain steady state metabolism of cartilage proteoglycans over the…”
Get full text

The interaction between retinoic acid and the transforming growth factors-beta in calf articular cartilage organ cultures by Morales, T I, Roberts, A B

“…In calf articular cartilage organ cultures, retinoic acid depressed proteoglycan anabolism to levels approximately 10% of control values and increased their…”
Get more information

Effects of interleukin-1 and lipopolysaccharides on protein and carbohydrate metabolism in bovine articular cartilage organ cultures by Morales, T I, Hascall, V C

“…The long term (18 day) metabolic response of bovine articular cartilage to treatment with either E. Coli lipopolysaccharide (LPS) or interleukin 1 was studied…”
Get more information

The Role and Content of Endogenous Insulin-Like Growth Factor-Binding Proteins in Bovine Articular Cartilage by Morales, Teresa I.

“…Previous work identified insulin-like growth factor (IGF)-binding proteins (IGF-BPs) in chondrocyte culture fluids, but the relationship of these proteins to…”
Get full text

The Insulin-like Growth Factors (IGFs) I and II Bind to Articular Cartilage via the IGF-binding Proteins by Bhakta, Nirav R., Garcia, A.Minerva, Frank, Eliot H., Grodzinsky, Alan J., Morales, Teresa I.

“…Bovine articular cartilage discs (3 mm diameter × 400 μm thick) were equilibrated in buffer containing125I-insulin-like growth factor (IGF)-I (4 °C) ±…”
Get full text

PZ peptidase from chick embryos: purification, properties, and action on collagen peptides by Morales, T.I, Woessner, J.F. Jr

“…PZ-peptidase is an endopeptidase that cleaves the synthetic substrate developed for clostridial collagenase,…”
Get full text

Characterization of the metalloproteinase inhibitor produced by bovine articular chondrocyte cultures by Morales, T I, Kuettner, K E, Howell, D S, Woessner, J F

“…Primary cultures of bovine articular chondrocytes release a latent metalloproteinase which is activated by incubation with organomercurials to degrade…”
Get more information

Factors involved in the regulation of proteoglycan metabolism in articular cartilage by Morales, T I, Hascall, V C

Get more information

Biosynthesis and turnover of proteoglycans in organ culture of bovine articular cartilage by Hascall, V C, Morales, T I, Hascall, G K, Handley, C J, McQuillan, D J

“…The biosynthesis and turnover of proteoglycans (PG) in organ cultures of bovine metacarpalphalangeal cartilage are described. After a few days in the presence…”
Get more information

Transforming growth factor-beta and insulin-like growth factor-1 restore proteoglycan metabolism of bovine articular cartilage after depletion by retinoic acid by Morales, T I

“…Previous studies showed that retinoic acid is a powerful resorbing agent for articular cartilage at physiological doses (10(-8) to 10(-10) M); the possible…”
Get more information