Search Results - "Morales, Lázaro"

The role of endogenous molecules in modulating pain through transient receptor potential vanilloid 1 (TRPV1) by Morales‐Lázaro, Sara L., Simon, Sidney A., Rosenbaum, Tamara

“…Key points •  TRPV1 (transient receptor potential vanilloid 1) channels are found throughout the body in epithelial cells and in peripheral and central…”
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TRP channels: a journey towards a molecular understanding of pain by Rosenbaum, Tamara, Morales-Lázaro, Sara L., Islas, León D.

“…The perception of nociceptive signals, which are translated into pain, plays a fundamental role in the survival of organisms. Because pain is linked to a…”
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Inhibition of TRPV1 channels by a naturally occurring omega-9 fatty acid reduces pain and itch by Morales-Lázaro, Sara L., Llorente, Itzel, Sierra-Ramírez, Félix, López-Romero, Ana E., Ortíz-Rentería, Miguel, Serrano-Flores, Barbara, Simon, Sidney A., Islas, León D., Rosenbaum, Tamara

“…The transient receptor potential vanilloid 1 (TRPV1) ion channel is mainly found in primary nociceptive afferents whose activity has been linked to…”
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Regulation of ThermoTRP Channels by PIP2 and Cholesterol by Rosenbaum, Tamara, Morales-Lázaro, Sara L

“…Transient receptor potential (TRP) ion channels are proteins that are expressed by diverse tissues and that play pivotal functions in physiology. These…”
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TRPV4: A Physio and Pathophysiologically Significant Ion Channel by Rosenbaum, Tamara, Benítez-Angeles, Miguel, Sánchez-Hernández, Raúl, Morales-Lázaro, Sara Luz, Hiriart, Marcia, Morales-Buenrostro, Luis Eduardo, Torres-Quiroz, Francisco

“…Transient Receptor Potential (TRP) channels are a family of ion channels whose members are distributed among all kinds of animals, from invertebrates to…”
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Cholesterol as a Key Molecule That Regulates TRPV1 Channel Function by Morales-Lázaro, Sara L, Rosenbaum, Tamara

“…Cholesterol is the one of the major constituents of cell membranes providing these structures with a certain degree of rigidity. Proteins, such as ion…”
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Epithelia-Sensory Neuron Cross Talk Underlies Cholestatic Itch Induced by Lysophosphatidylcholine by Chen, Yong, Wang, Zi-Long, Yeo, Michele, Zhang, Qiao-Juan, López-Romero, Ana E., Ding, Hui-Ping, Zhang, Xin, Zeng, Qian, Morales-Lázaro, Sara L., Moore, Carlene, Jin, Ying-Ai, Yang, Huang-He, Morstein, Johannes, Bortsov, Andrey, Krawczyk, Marcin, Lammert, Frank, Abdelmalek, Manal, Diehl, Anna Mae, Milkiewicz, Piotr, Kremer, Andreas E., Zhang, Jennifer Y., Nackley, Andrea, Reeves, Tony E., Ko, Mei-Chuan, Ji, Ru-Rong, Rosenbaum, Tamara, Liedtke, Wolfgang

“…Limited understanding of pruritus mechanisms in cholestatic liver diseases hinders development of antipruritic treatments. Previous studies implicated…”
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Molecular Interplay Between the Sigma-1 Receptor, Steroids, and Ion Channels by Morales-Lázaro, Sara L, González-Ramírez, Ricardo, Rosenbaum, Tamara

“…Cell excitability is tightly regulated by the activity of ion channels that allow for the passage of ions across cell membranes. Ion channel activity is…”
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Enhanced nuclear protein export in premature aging and rescue of the progeria phenotype by modulation of CRM1 activity by García‐Aguirre, Ian, Alamillo‐Iniesta, Alma, Rodríguez‐Pérez, Ruth, Vélez‐Aguilera, Griselda, Amaro‐Encarnación, Elianeth, Jiménez‐Gutiérrez, Elizabeth, Vásquez‐Limeta, Alejandra, Samuel Laredo‐Cisneros, Marco, Morales‐Lázaro, Sara L., Tiburcio‐Félix, Reynaldo, Ortega, Arturo, Magaña, Jonathan J, Winder, Steve J., Cisneros, Bulmaro

“…The study of Hutchinson–Gilford progeria syndrome (HGPS) has provided important clues to decipher mechanisms underlying aging. Progerin, a mutant lamin A,…”
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Streptozotocin-Induced Diabetic Rats Showed a Differential Glycine Receptor Expression in the Spinal Cord: A GlyR Role in Diabetic Neuropathy by Velázquez-Flores, Miguel Ángel, Sánchez-Chávez, Gustavo, Morales-Lázaro, Sara L., Ruiz Esparza-Garrido, Ruth, Canizales-Ontiveros, Alejandro, Salceda, Rocío

“…In the spinal cord, attenuation of the inhibitory action of glycine is related to an increase in both inflammatory and diabetic neuropathic pain; however, the…”
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Lysophosphatidic acid directly activates TRPV1 through a C-terminal binding site by Nieto-Posadas, Andrés, Picazo-Juárez, Giovanni, Llorente, Itzel, Jara-Oseguera, Andrés, Morales-Lázaro, Sara, Escalante-Alcalde, Diana, Islas, León D, Rosenbaum, Tamara

“…Lysophosphatidic acid (LPA), a lipid that induces neuropathic pain, functions by binding directly to the ion channel TRPV1 independently from the G…”
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Lysophosphatidic Acid and Ion Channels as Molecular Mediators of Pain by Juárez-Contreras, Rebeca, Rosenbaum, Tamara, Morales-Lázaro, Sara L

“…Lysophosphatidic acid or LPA is a phospholipid which has been extensively linked to the generation and maintenance of pain. Several ion channels have also been…”
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The Influence of Sex Steroid Hormone Fluctuations on Capsaicin-Induced Pain and TRPV1 Expression by Mota-Carrillo, Edgardo, Juárez-Contreras, Rebeca, González-Ramírez, Ricardo, Luis, Enoch, Morales-Lázaro, Sara Luz

“…Sexual dimorphism among mammals includes variations in the pain threshold. These differences are influenced by hormonal fluctuations in females during the…”
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TRPV1 Channel: A Noxious Signal Transducer That Affects Mitochondrial Function by Juárez-Contreras, Rebeca, Méndez-Reséndiz, Karina Angélica, Rosenbaum, Tamara, González-Ramírez, Ricardo, Morales-Lázaro, Sara Luz

“…The Transient Receptor Vanilloid 1 (TRPV1) or capsaicin receptor is a nonselective cation channel, which is abundantly expressed in nociceptors. This channel…”
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Multiple Mechanisms of Regulation of Transient Receptor Potential Ion Channels by Cholesterol by Morales-Lázaro, Sara L, Rosenbaum, Tamara

“…The transient receptor potential (TRP) family of ion channels is constituted by several nonselective cation channels that are activated by diverse stimuli and…”
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CBD Reverts the Mesenchymal Invasive Phenotype of Breast Cancer Cells Induced by the Inflammatory Cytokine IL-1β by García-Morales, Lázaro, Castillo, Aída M, Tapia Ramírez, José, Zamudio-Meza, Horacio, Domínguez-Robles, Ma Del Carmen, Meza, Isaura

“…Cannabidiol (CBD) has been used to treat a variety of cancers and inflammatory conditions with controversial results. In previous work, we have shown that…”
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Identification of Dp140 and α1-syntrophin as novel molecular interactors of the neuronal CaV2.1 channel by Leyva-Leyva, Margarita, Sandoval, Alejandro, Morales-Lázaro, Sara Luz, Corzo-López, Alejandra, Felix, Ricardo, González-Ramírez, Ricardo

“…The primary function of dystrophin is to form a link between the cytoskeleton and the extracellular matrix. In addition to this crucial structural function,…”
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A painful link between the TRPV1 channel and lysophosphatidic acid by Morales-Lázaro, Sara L., Rosenbaum, Tamara

“…The Transient Receptor Potential Vanilloid 1 (TRPV1) ion channel is expressed mainly by sensory neurons that detect noxious stimuli from the environment such…”
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Steroids and TRP Channels: A Close Relationship by Méndez-Reséndiz, Karina Angélica, Enciso-Pablo, Óscar, González-Ramírez, Ricardo, Juárez-Contreras, Rebeca, Rosenbaum, Tamara, Morales-Lázaro, Sara Luz

“…Transient receptor potential (TRP) channels are remarkable transmembrane protein complexes that are essential for the physiology of the tissues in which they…”
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Structural Determinants of the Transient Receptor Potential 1 (TRPV1) Channel Activation by Phospholipid Analogs by Morales-Lázaro, Sara L., Serrano-Flores, Barbara, Llorente, Itzel, Hernández-García, Enrique, González-Ramírez, Ricardo, Banerjee, Souvik, Miller, Duane, Gududuru, Veeresh, Fells, James, Norman, Derek, Tigyi, Gabor, Escalante-Alcalde, Diana, Rosenbaum, Tamara

“…The transient receptor potential vanilloid 1 (TRPV1) ion channel is a polymodal protein that responds to various stimuli, including capsaicin (the pungent…”
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