Search Results - "Morales, Fatima Saldana"
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Microbiota manipulation to increase macrophage IL-10 improves colitis and limits colitis-associated colorectal cancer
Published in Gut microbes (31-12-2022)“…Inflammatory bowel disease (IBD) is a chronic life-long inflammatory disease affecting almost 2 million Americans. Although new biologic therapies have been…”
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Interleukin-1β secretion induced by mucosa-associated gut commensal bacteria promotes intestinal barrier repair
Published in Gut microbes (01-01-2022)“…The gut microbiota is essential for maintenance and repair of the intestinal epithelial barrier. As shifts in both intestinal epithelial barrier function and…”
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Healthy Intestinal Function Relies on Coordinated Enteric Nervous System, Immune System, and Epithelium Responses
Published in Gut microbes (01-01-2021)“…During both health and disease, a coordinated response between the epithelium, immune system, and enteric nervous system is required for proper intestinal…”
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Thymic development of gut-microbiota-specific T cells
Published in Nature (London) (17-06-2021)“…Humans and their microbiota have coevolved a mutually beneficial relationship in which the human host provides a hospitable environment for the microorganisms…”
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Off-Target Effects of Clozapine-N-Oxide on the Chemosensory Reflex Are Masked by High Stress Levels
Published in Frontiers in physiology (22-05-2019)“…Respiratory chemosensory circuits are implicated in several physiological and behavioral disorders ranging from sudden infant death syndrome to panic disorder…”
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Thymic microbiota-specific T cells role in intestinal inflammation
Published in The Journal of immunology (1950) (01-05-2021)“…Inflammatory bowel disease (IBD) patients, including Crohn’s disease and ulcerative colitis, exhibit dysregulated immune responses. Although IBD etiology…”
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Microbiota regulation of intestinal inflammation influences colorectal cancer
Published in The Journal of immunology (1950) (01-05-2022)“…Inflammatory bowel disease (IBD) patients with poorly controlled intestinal inflammation are at an elevated risk for colorectal cancer (CRC). IBD patients…”
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Microbiota regulation of development of thymic microbiota-specific T cells
Published in The Journal of immunology (1950) (01-05-2022)“…While exposure to microbial antigens in peripheral sites causes expansion of antigen-specific T cells, a role for antigen-specific expansion had not been…”
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Select mucosa-associated intestinal commensal bacteria promote gut barrier repair by inducing IL-1b production
Published in The Journal of immunology (1950) (01-05-2022)“…Microbiota interactions with host tissue support proper intestinal functions. In diseases such as inflammatory bowel disease, microbial shift along with…”
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Microbiota regulation of thymic microbiota-specific T cell development
Published in The Journal of immunology (1950) (01-05-2023)“…While exposure to microbial antigens in peripheral sites causes expansion and differentiation of antigen-specific T cells, a role for antigen-specific…”
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Embryonic Rhombomere Hindbrain Patterning Delineates Distinct Functional Neuron Populations in the Adult Central Noradrenergic System
Published in The FASEB journal (01-04-2017)“…Abstract only Central noradrenergic (NA) neurons are a critical participant in the brainstem networks that maintain respiratory homeostasis. However,…”
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Gut Microbiome is Dispensable for Normal Respiratory Function and Chemoreflexes in Adult Mice
Published in The FASEB journal (01-04-2019)“…Increasing evidence indicates that changes in respiratory homeostasis and disordered breathing, such as obstructive sleep apnea, intermittent hypoxia or…”
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Intestinal colonization with IL-10 inducing adherent E. coli protects from intestinal inflammation and tumor development
Published in The Journal of immunology (1950) (01-05-2020)“…Colorectal cancer (CRC) is the third most common and third most deadly cancer in the US. Chronic intestinal inflammation corresponds with advanced disease…”
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Pharmacogenetic Modulation of the Noradrenergic System Reveals Protective and Vulnerable Roles in the Neonate Autoresuscitation Reflex
Published in The FASEB journal (01-04-2019)“…A key feature of neonatal respiration is the autoresuscitation reflex, which restarts breathing and cardiac function after an infant has fallen into…”
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FOREBRAIN ALZHEIMER'S DISEASE PATHOLOGY DOES NOT RESULT IN DISORDERED BREATHING IN MICE
Published in The FASEB journal (01-04-2019)“…Alzheimer's disease (AD) is a chronic neurodegenerative disease. Early presentation starts with short‐term memory loss that progresses to disorientation and…”
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Interleukin-1β secretion induced by mucosal-associated gut commensal bacteria promotes intestinal barrier repair
Published in The Journal of immunology (1950) (01-05-2021)“…It is known that the gut commensal bacteria support intestinal epithelial barrier integrity. However, how specific microbes regulate barrier integrity is not…”
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Intestinal commensal bacteria promote gut barrier repair through non-canonical inflammasome pathway activation
Published in The Journal of immunology (1950) (01-05-2020)“…The intestinal epithelial barrier critically separates exogenous microbes from our internal tissues. Signals from commensal microbes are known to support…”
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