Search Results - "Morales, Diana K"
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Sugarcoating it: Enterococcal polysaccharides as key modulators of host–pathogen interactions
Published in PLoS pathogens (09-09-2021)“…CP, capsule polysaccharide; EPA, enterococcal polysaccharide antigen; LTA, lipoteichoic acid; PG, peptidoglycan; polyGlcNAc, β-(1,6)-GlcNAc polymers; WTA, wall…”
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Candida albicans interactions with bacteria in the context of human health and disease
Published in PLoS pathogens (01-04-2010)“…Humans are colonized by diverse populations of bacteria and fungi when in a healthy state and in the settings of disease, and the interactions between these…”
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Control of Candida albicans metabolism and biofilm formation by Pseudomonas aeruginosa phenazines
Published in mBio (29-01-2013)“…Candida albicans has developmental programs that govern transitions between yeast and filamentous morphologies and between unattached and biofilm lifestyles…”
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Light/Dark and Temperature Cycling Modulate Metabolic Electron Flow in Pseudomonas aeruginosa Biofilms
Published in mBio (30-08-2022)“…Sunlight drives phototrophic metabolism, which affects redox conditions and produces substrates for nonphototrophs. These environmental parameters fluctuate…”
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Farnesol, a common sesquiterpene, inhibits PQS production in Pseudomonas aeruginosa
Published in Molecular microbiology (01-08-2007)“…Farnesol is a sesquiterpene produced by many organisms, including the fungus Candida albicans. Here, we report that the addition of farnesol to cultures of…”
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Remodeling of the Enterococcal Cell Envelope during Surface Penetration Promotes Intrinsic Resistance to Stress
Published in mBio (20-12-2022)“…Enterococcus faecalis is a normal commensal of the human gastrointestinal tract (GIT). However, upon disruption of gut homeostasis, this nonmotile bacterium…”
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Inflammatory ER stress responses dictate the immunopathogenic progression of systemic candidiasis
Published in The Journal of clinical investigation (01-09-2023)“…Recognition of pathogen-associated molecular patterns can trigger the inositol-requiring enzyme 1 α (IRE1α) arm of the endoplasmic reticulum (ER) stress…”
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Analysis of Candida albicans mutants defective in the Cdk8 module of mediator reveal links between metabolism and biofilm formation
Published in PLoS genetics (01-10-2014)“…Candida albicans biofilm formation is a key virulence trait that involves hyphal growth and adhesin expression. Pyocyanin (PYO), a phenazine secreted by…”
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PolyGlcNAc-containing exopolymers enable surface penetration by non-motile Enterococcus faecalis
Published in PLoS pathogens (01-02-2019)“…Bacterial pathogens have evolved strategies that enable them to invade tissues and spread within the host. Enterococcus faecalis is a leading cause of local…”
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Specific control of Pseudomonas aeruginosa surface-associated behaviors by two c-di-GMP diguanylate cyclases
Published in mBio (29-10-2010)“…The signaling nucleotide cyclic diguanylate (c-di-GMP) regulates the transition between motile and sessile growth in a wide range of bacteria. Understanding…”
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Exopolysaccharide-mediated surface penetration as new virulence trait in Enterococcus faecalis
Published in Communicative & integrative biology (2019)“…Enterococcus faecalis is a commensal bacterium that normally inhabits the gastrointestinal tract of humans. This non-motile microorganism can also cause lethal…”
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The Pseudomonas aeruginosa efflux pump MexGHI-OpmD transports a natural phenazine that controls gene expression and biofilm development
Published in Proceedings of the National Academy of Sciences - PNAS (21-06-2016)“…Redox-cycling compounds, including endogenously produced phenazine antibiotics, induce expression of the efflux pump MexGHI-OpmD in the opportunistic pathogen…”
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Candida albicans- produced farnesol stimulates Pseudomonas quinolone signal production in LasR-defective Pseudomonas aeruginosa strains
Published in Microbiology (Society for General Microbiology) (01-10-2010)“…Candida albicans has been previously shown to stimulate the production of Pseudomonas aeruginosa phenazine toxins in dual-species colony biofilms. Here, we…”
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Antifungal mechanisms by which a novel Pseudomonas aeruginosa phenazine toxin kills Candida albicans in biofilms
Published in Molecular microbiology (01-12-2010)“…Summary Pseudomonas aeruginosa produces several phenazines including the recently described 5‐methyl‐phenazine‐1‐carboxylic acid (5MPCA), which exhibits a…”
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Transgelin 2 guards T cell lipid metabolism and antitumour function
Published in Nature (London) (23-10-2024)“…Mounting effective immunity against pathogens and tumours relies on the successful metabolic programming of T cells by extracellular fatty acids …”
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Dietary Fructose Alters the Composition, Localization, and Metabolism of Gut Microbiota in Association With Worsening Colitis
Published in Cellular and molecular gastroenterology and hepatology (01-01-2021)“…The incidence of inflammatory bowel diseases has increased over the last half century, suggesting a role for dietary factors. Fructose consumption has…”
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Enterococcal-host interactions in the gastrointestinal tract and beyond
Published in FEMS microbes (2024)“…The gastrointestinal tract (GIT) is typically considered the natural niche of enterococci. However, these bacteria also inhabit extraintestinal tissues, where…”
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Candida albicans Interactions with Bacteria in the Context of Human Health and Disease: e1000886
Published in PLoS pathogens (01-04-2010)“…[...]several studies demonstrate an association between C. albicans and oral bacteria such as Streptococcus (Figure 1A), Actinomyces, and Fusobacterium species…”
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Analysis of Candida albicans Mutants Defective in the Cdk8 Module of Mediator Reveal Links between Metabolism and Biofilm Formation: e1004567
Published in PLoS genetics (01-10-2014)“…Candida albicans biofilm formation is a key virulence trait that involves hyphal growth and adhesin expression. Pyocyanin (PYO), a phenazine secreted by…”
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One Welfare for all: Associations between sheep welfare indicators and producers’ mental health
Published in Revista MVZ Córdoba (2023)“…Objective. The objective of this observational cross-sectional study was to investigate associations between farmers’ mental health scores for stress, anxiety,…”
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