Search Results - "Morales, Cyndi R"

Spliced X-Box Binding Protein 1 Couples the Unfolded Protein Response to Hexosamine Biosynthetic Pathway by Wang, Zhao V., Deng, Yingfeng, Gao, Ningguo, Pedrozo, Zully, Li, Dan L., Morales, Cyndi R., Criollo, Alfredo, Luo, Xiang, Tan, Wei, Jiang, Nan, Lehrman, Mark A., Rothermel, Beverly A., Lee, Ann-Hwee, Lavandero, Sergio, Mammen, Pradeep P.A., Ferdous, Anwarul, Gillette, Thomas G., Scherer, Philipp E., Hill, Joseph A.

“…The hexosamine biosynthetic pathway (HBP) generates uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) for glycan synthesis and O-linked GlcNAc (O-GlcNAc)…”
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Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy by Cao, Dian J, Wang, Zhao V, Battiprolu, Pavan K, Jiang, Nan, Morales, Cyndi R, Kong, Yongli, Rothermel, Beverly A, Gillette, Thomas G, Hill, Joseph A

“…Histone deacetylases (HDACs) regulate cardiac plasticity; however, their molecular targets are unknown. As autophagy contributes to pathological cardiac…”
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Inhibition of class I histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression by Morales, Cyndi R, Li, Dan L, Pedrozo, Zully, May, Herman I, Jiang, Nan, Kyrychenko, Viktoriia, Cho, Geoffrey W, Kim, Soo Young, Wang, Zhao V, Rotter, David, Rothermel, Beverly A, Schneider, Jay W, Lavandero, Sergio, Gillette, Thomas G, Hill, Joseph A

“…Altering chromatin structure through histone posttranslational modifications has emerged as a key driver of transcriptional responses in cells. Modulation of…”
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Tuning flux: autophagy as a target of heart disease therapy by Xie, Min, Morales, Cyndi R, Lavandero, Sergio, Hill, Joseph A

“…PURPOSE OF REVIEWDespite maximum medical and mechanical support therapy, heart failure remains a relentlessly progressive disorder with substantial morbidity…”
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Oxidative stress and autophagy in cardiovascular homeostasis by Morales, Cyndi R, Pedrozo, Zully, Lavandero, Sergio, Hill, Joseph A

“…Autophagy is an evolutionarily ancient process of intracellular protein and organelle recycling required to maintain cellular homeostasis in the face of a wide…”
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Activation of Autophagic Flux Blunts Cardiac Ischemia/Reperfusion Injury by Xie, Min, Cho, Geoffrey W., Kong, Yongli, Li, Dan L., Altamirano, Francisco, Luo, Xiang, Morales, Cyndi R., Jiang, Nan, Schiattarella, Gabriele G., May, Herman I., Medina, Jessica, Shelton, John M., Ferdous, Anwarul, Gillette, Thomas G., Hill, Joseph A.

“…[Figure: see text]…”
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Polycystin-1 Is a Cardiomyocyte Mechanosensor That Governs L-Type Ca2+ Channel Protein Stability by Pedrozo, Zully, Criollo, Alfredo, Battiprolu, Pavan K, Morales, Cyndi R, Contreras-Ferrat, Ariel, Fernández, Carolina, Jiang, Nan, Luo, Xiang, Caplan, Michael J, Somlo, Stefan, Rothermel, Beverly A, Gillette, Thomas G, Lavandero, Sergio, Hill, Joseph A

“…L-type calcium channel activity is critical to afterload-induced hypertrophic growth of the heart. However, the mechanisms governing mechanical stress-induced…”
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Epigenetic regulation in heart failure by Kim, Soo Young, Morales, Cyndi R, Gillette, Thomas G, Hill, Joseph A

“…PURPOSE OF REVIEWThis article provides an overview, highlighting recent findings, of a major mechanism of gene regulation and its relevance to the…”
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Regulator of Calcineurin 1 helps coordinate whole‐body metabolism and thermogenesis by Rotter, David, Peiris, Heshan, Grinsfelder, D Bennett, Martin, Alyce M, Burchfield, Jana, Parra, Valentina, Hull, Christi, Morales, Cyndi R, Jessup, Claire F, Matusica, Dusan, Parks, Brian W, Lusis, Aldons J, Nguyen, Ngoc Uyen Nhi, Oh, Misook, Iyoke, Israel, Jakkampudi, Tanvi, McMillan, D Randy, Sadek, Hesham A, Watt, Matthew J, Gupta, Rana K, Pritchard, Melanie A, Keating, Damien J, Rothermel, Beverly A

“…Increasing non‐shivering thermogenesis (NST), which expends calories as heat rather than storing them as fat, is championed as an effective way to combat…”
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NADPH oxidase-dependent and -independent mechanisms of reported inhibitors of reactive oxygen generation by Gatto, Jr, Gregory J, Ao, Zhaohui, Kearse, Michael G, Zhou, Mei, Morales, Cyndi R, Daniels, Erin, Bradley, Benjamin T, Goserud, Matthew T, Goodman, Krista B, Douglas, Stephen A, Harpel, Mark R, Johns, Douglas G

“…NADPH oxidase isoform-2 (NOX2) generates reactive oxygen species (ROS) that contribute to neurodegenerative and cardiovascular pathologies. However, validation…”
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Activation of Autophagic Flux Blunts Cardiac Ischemia/Reperfusion Injury by Xie, Min, Cho, Geoffrey W., Kong, Yongli, Li, Dan L., Altamirano, Francisco, Luo, Xiang, Morales, Cyndi R., Jiang, Nan, Schiattarella, Gabriele G., May, Herman I., Medina, Jessica, Shelton, John, Ferdous, Anwarul, Gillette, Thomas G., Hill, Joseph A.

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Polycystin-1 Is a Cardiomyocyte Mechanosensor That Governs L-Type Ca 2+ Channel Protein Stability by Pedrozo, Zully, Criollo, Alfredo, Battiprolu, Pavan K., Morales, Cyndi R., Contreras-Ferrat, Ariel, Fernández, Carolina, Jiang, Nan, Luo, Xiang, Caplan, Michael J., Somlo, Stefan, Rothermel, Beverly A., Gillette, Thomas G., Lavandero, Sergio, Hill, Joseph A.

“…Background— L-type calcium channel activity is critical to afterload-induced hypertrophic growth of the heart. However, the mechanisms governing mechanical…”
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