Search Results - "Morais, Pedro Alves Bezerra"
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Thymol as an Interesting Building Block for Promising Fungicides against Fusarium solani
Published in Journal of agricultural and food chemistry (30-06-2021)“…The semisynthesis of 15 new thymol derivatives was achieved through Williamson synthesis and copper-catalyzed azide–alkyne cycloaddition (CuAAC) approaches…”
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Novel [6]-gingerol Triazole Derivatives and their Antiproliferative Potential against Tumor Cells
Published in Current topics in medicinal chemistry (01-01-2020)“…Effective cancer treatment is a major public health challenge. The limitations of current therapies and their adverse effects reduce the efficacy of treatment,…”
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Bioactivity of Meliaceae, Amaryllidaceae, Solanaceae and Amaranthaceae plant aqueous extracts against the cattle tick Rhipicephalus microplus
Published in Natural product research (17-11-2022)“…Commercial synthetic acaricides have selected resistant populations of , and generate residues in the environment or in milk/cattle products. In this study,…”
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4
Synthesis and Phytotoxic Evaluation of Isatin Derivatives Supported by 3D-QSAR Study
Published in Journal of agricultural and food chemistry (11-01-2023)“…Concerned about weed infestation, a major threat to food production and herbicide resistance that interferes in the mechanism of action of the main herbicides,…”
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Synthesis and Fungicide Activity on Asperisporium caricae of Glycerol Derivatives Bearing 1,2,3-Triazole Fragments
Published in Journal of agricultural and food chemistry (10-05-2023)“…In agriculture, the control of fungal infections is essential to improve crop quality and productivity. This study describes the preparation and fungicidal…”
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Design and Synthesis of Eugenol Derivatives Bearing a 1,2,3-Triazole Moiety for Papaya Protection against Colletotrichum gloeosporioides
Published in Journal of agricultural and food chemistry (21-05-2024)“…A series of 19 novel eugenol derivatives containing a 1,2,3-triazole moiety was synthesized via a two-step process, with the key step being a…”
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Anti‐Candida, docking studies, and in vitro metabolism‐mediated cytotoxicity evaluation of Eugenol derivatives
Published in Chemical biology & drug design (01-02-2023)“…The high morbidity and mortality rates of Candida infections, especially among immunocompromised patients, are related to the increased resistance rate of…”
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Design, synthesis, docking studies and bioactivity evaluation of 1,2,3-triazole eugenol derivatives
Published in Future medicinal chemistry (16-09-2024)“…The design, synthesis, docking studies and evaluation of the antifungal and cytotoxic properties of eugenol (EUG) containing 1,2,3-triazole derivatives are…”
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SYNTHESIS OF GLYCEROL-FLUORINATED TRIAZOLE DERIVATIVES AND EVALUATION OF THEIR FUNGICIDAL ACTIVITY
Published in Química Nova (01-01-2022)“…The control of fungal species in agriculture is mainly conducted with the use of contact or systemic fungicides. However, environmental and human health…”
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10
Opening the door to the development of novel Abl kinase inhibitors
Published in Future medicinal chemistry (01-11-2016)“…The discovery of the importance of kinase activity and its relationship to the emergence and proliferation of cancer cells, due to changes in normal…”
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In silico design and search for acetylcholinesterase inhibitors in Alzheimer's disease with a suitable pharmacokinetic profile and low toxicity
Published in Future medicinal chemistry (01-06-2011)“…Alzheimer's disease is a complex neurodegenerative disorder of the central nervous system, characterized by amyloid-β deposits, τ-protein aggregation,…”
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12
Semisynthetic p‐Coumaric Acid Derivatives as Lead Dual Inhibitors Against DPP‐IV and GSK‐3β for Antidiabetic Therapy
Published in Chemical biology & drug design (01-11-2024)“…ABSTRACT Type 2 diabetes mellitus is a dramatically increasing global public health challenge. The prevalence is projected almost double, from 194 million in…”
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13
New thymol-derived triazole exhibits promising activity against Trichophyton rubrum
Published in Brazilian journal of microbiology (01-06-2024)“…Fungal infections have emerged worldwide, and azole antifungals are widely used to control these infections. However, the emergence of antifungal resistance…”
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SÍNTESE DE DERIVADOS TRIAZÓLICOS DO ÁCIDO CAFEÍCO
Published in Revista UniVap (05-01-2017)“…O ácido cafeíco demonstrou interessante atividade antiproliferativa contra linhagens de células cancerígenas testadas, sobretudo para células do colo do útero…”
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15
Bioactivity of Meliaceae, Amaryllidaceae, Solanaceae and Amaranthaceae plant aqueous extracts against the cattle tick Rhipicephalus microplus
Published in Natural Product Research (17-11-2022)“…Commercial synthetic acaricides have selected resistant populations of Rhipicephalus microplus, and generate residues in the environment or in milk/cattle…”
Get full text
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