Predictors of Epilepsy in Children With Cerebrovascular Disease
Post-stroke seizures and epilepsy in children are a common but understudied complication. In this retrospective cohort study, the medical records of 65 children aged 0 to 18 years were analyzed to assess the risk of post-stroke seizures, detect the prevalence of post-stroke epilepsy, and ascertain w...
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| Published in: | Journal of child neurology Vol. 28; no. 11; pp. 1387 - 1391 |
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| Main Authors: | , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Los Angeles, CA
SAGE Publications
01-11-2013
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| Subjects: | |
| Online Access: | Get full text |
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| Summary: | Post-stroke seizures and epilepsy in children are a common but understudied complication. In this retrospective cohort study, the medical records of 65 children aged 0 to 18 years were analyzed to assess the risk of post-stroke seizures, detect the prevalence of post-stroke epilepsy, and ascertain which risk factors are associated with this condition in children. Forty-two patients (64.6%) had epileptic seizures following stroke (35 early, 7 late-onset), with most (78.5%) occurring in the first 24 hours. Nineteen children (29.2%) developed post-stroke epilepsy, which was significantly more common among patients with late-onset seizures (P = .034). There was a significant association between cortical involvement and development of epilepsy (P = .01). After Poisson regression, the relative risk of epilepsy was calculated as 2.4 in children with late-onset post-stroke seizures (95% confidence interval, 1.4-3.9; P = .001) and 3.7 in children with cortical involvement (95% confidence interval, 1.4-9.7; P = .009). |
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| Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2 |
| ISSN: | 0883-0738 1708-8283 |
| DOI: | 10.1177/0883073812464270 |