Search Results - "Moraga, Paloma"

Evaluation of factors associated with recruitment rates in early phase clinical trials based on the European Clinical Trials Register data by Moraga Alapont, Paloma, Prieto, Paula, Urroz, Mikel, Jiménez, María, Carcas, Antonio J., Borobia, Alberto M.

“…Effective participant recruitment is a critical challenge in clinical trials. Inadequate enrollment of participants can precipitate delays, escalated costs,…”
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Academia and industry agreement on a feasibility tool for first‐time‐in‐human clinical trial units by Moraga, Paloma, Prieto, Paula, Conradie, Almari, Benhayoun, Majda, Rousell, Vicki, Davy, Maria, Fuhr, Uwe, Antonijoan Arbos, Rosa, Abad‐Santos, Francisco, Portolés, Antonio, Van Duinen, Jolanda, Carcas, Antonio J., Borobia, Alberto M.

“…First‐time‐in‐human (FTIH) trials are designed to generate information on the safety, tolerability, as well as the pharmacokinetic and pharmacodynamics profile…”
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Assays to Study IRE1 Activation and Signaling by Moraga, Paloma, Aravena, Raul, Urra, Hery, Hetz, Claudio

“…The endoplasmic reticulum (ER) stress sensor IRE1 is a a major player of the unfolded protein response (UPR), the main pathway driving adaptation processes to…”
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Impact of Complete Revascularization in the ISCHEMIA Trial by Rhodes, Grace, Mavromatis, Kreton, Dressler, Ovidiu, Nath, Ranjit K., Shaw, Leslee J., Fremes, Stephen E., Maron, David J., Harrington, Robert, Berger, Jeffrey, Ballantyne, Christie, Buller, Chris, Held, Claes, Jiang, Lixin, Kohsaka, Shun, Maggioni, Aldo, Mancini, John, Calfas, Karen, Stone, Peter, Fremes, Stephen, Mack, Michael, Rao, Anupama, Sabik, Joe, de Bruyne, Bernard, Lefevre, Thierry, Moses, Jeffrey, Mahaffey, Ken, Hauptman, Paul, Laddu, Abhay A., Simoons, Maarten, Waters, David, Esposito, Gerard, Kanters, Jeffrey, Kwong, Raymond, Harrell, Frank, Newby, Kristin, Bugiardini, Raffaele, Leipsic, Jonathan, Friedman, Lawrence, Berg, Jessica, DeMets, David, Nwosu, Samuel, Mavromichalis, Stephanie, Gabriel, Andre, Naumova, Anna, Chang, Michelle, Yakubov, Solomon, Yee, Michelle, Hogan, Isabelle, Qelaj, Albertina, Van Loo, Kerrie, Gilsenan, Margaret, Mohamed, Samaa, Setang, Vincent, Xavier, Mark, Bagai, Akshay, Garg, Jyotsna, Heath, Anne, Leimberger, Jeff, Thompson, Omar, Ussery, Sheri, Williams, Mary (Kaye), Anstrom, Kevin, Blount, Janet, Harding, Tina, Knight, J David, O’Neal, Betsy, Nugent, Karen, Phillips, Lawrence, Hayes, Sean W., Friedman, John D., Miranda-Peats, Romalisa, Hung, Judy, Streif, Mary, Alfonso, Maria A., Corral, Maria P., Jankovic, Ivana, Elmore, Kimberly, Gomez, Millie, Ceseri, Martina, Orso, Francesco, Sarti, Laura, Tricoli, Martinia, Barbosa, Lilian Mazza, Colaiácovo Soares, Tamara, de Carvalho Maffei, Natalia, Kawakami, Anelise, Oliveira, Janaina, Spindler, Caroline, Dai, Hao, Xie, Qiulan, Zhang, Jianxin, Zhang, Ning, Zhong, Hui, Martin, Maria Eugenia, Moraga, Paloma, Fernandez, Sara, Luyten, Ann, Robesyn, Valerie, Kumar, Vijay, Ramasamy, Karthik

“…Anatomic complete revascularization (ACR) and functional complete revascularization (FCR) have been associated with reduced death and myocardial infarction…”
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Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomised, double-blind, placebo-controlled phase 3 trial by Trøseid, Marius, Arribas, José R, Assoumou, Lambert, Holten, Aleksander Rygh, Poissy, Julien, Terzić, Vida, Mazzaferri, Fulvia, Baño, Jesús Rodríguez, Eustace, Joe, Hites, Maya, Joannidis, Michael, Paiva, José-Artur, Reuter, Jean, Püntmann, Isabel, Patrick-Brown, Thale D J H, Westerheim, Elin, Nezvalova-Henriksen, Katerina, Beniguel, Lydie, Dahl, Tuva Børresdatter, Bouscambert, Maude, Halanova, Monika, Péterfi, Zoltán, Tsiodras, Sotirios, Rezek, Michael, Briel, Matthias, Ünal, Serhat, Schlegel, Martin, Ader, Florence, Lacombe, Karine, Amdal, Cecilie Delphin, Rodrigues, Serge, Tonby, Kristian, Gaudet, Alexandre, Heggelund, Lars, Mootien, Joy, Johannessen, Asgeir, Møller, Jannicke Horjen, Pollan, Beatriz Diaz, Tveita, Anders Aune, Kildal, Anders Benjamin, Richard, Jean-Christophe, Dalgard, Olav, Simensen, Victoria Charlotte, Baldé, Aliou, de Gastines, Lucie, Del Álamo, Marta, Aydin, Burç, Lund-Johansen, Fridtjof, Trabaud, Mary-Anne, Diallo, Alpha, Halvorsen, Bente, Røttingen, John-Arne, Tacconelli, Evelina, Yazdanpanah, Yazdan, Olsen, Inge C, Costagliola, Dominique

“…Baricitinib has shown efficacy in hospitalized patients with COVID-19, but no placebo-controlled trials have focused specifically on severe/critical COVID,…”
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