Search Results - "Moraes Junior, Manoel Oliveira"

Next‐generation of melanoma researchers: Trainee perspectives from around the world by Webster, Marie R., Brathwaite, Roderick, Narula, Jeremy A. Bravo, Elad, Vissy M., Ma, Yanni, Ng, Mei Fong, Moraes Junior, Manoel Oliveira, Shabangu, Majahonkhe, Tsiavou, Christina, Villanueva, Jessie, Rebecca, Vito W.

“…The Society for Melanoma Research (SMR) was created 20 years ago and has unequivocally contributed to the vast progress of the field, particularly for the…”
Get full text

Design, Synthesis and Phenotypic Profiling of Simplified Gedatolisib Analogues by Costa, Caroline Marques Xavier, Aparecida-Silva, Cristiane, Gamba, Luis Eduardo Reina, de Melo, Thalita Neves, Barbosa, Gisele, Moraes Junior, Manoel Oliveira de, de Oliveira, Victoria Regina Thomaz, de Amorim, Carolinne Souza, Moraes, João A, Barreiro, Eliezer Jesus, Lima, Lídia Moreira

“…Targeted antitumour therapy has revolutionized the treatment of several types of tumours. Among the validated targets, phosphatidylinositol-3 kinase (PI3K)…”
Get full text

Discovery of sulfonyl hydrazone derivative as a new selective PDE4A and PDE4D inhibitor by lead-optimization approach on the prototype LASSBio-448: In vitro and in vivo preclinical studies by Nunes, Isabelle Karine da Costa, de Souza, Everton Tenório, Martins, Italo Rossi Roseno, Barbosa, Gisele, Moraes Junior, Manoel Oliveira de, Medeiros, Millena de Melo, Silva, Sheyla Welma Duarte, Balliano, Tatiane Luciano, da Silva, Bagnólia Araújo, Silva, Patrícia Machado Rodrigues, Carvalho, Vinicius de Frias, Martins, Marco Aurélio, Lima, Lidia Moreira

“…Phosphodiesterase 4 (PDE4) inhibitors have emerged as a new strategy to treat asthma and other lung inflammatory diseases. Searching for new PDE4 inhibitors,…”
Get full text

Peroxiredoxin-2 represses NRAS-mutated melanoma cells invasion by modulating EMT markers by Noma, Isabella Harumi Yonehara, Carvalho, Larissa Anastacio da Costa, Camarena, Denisse Esther Mallaupoma, Silva, Renaira Oliveira, Moraes Junior, Manoel Oliveira de, de Souza, Sophia Tavares, Newton-Bishop, Julia, Nsengimana, Jérémie, Maria-Engler, Silvya Stuchi

“…The second most common mutation in melanoma occurs in NRAS oncogene, being a more aggressive disease that has no effective approved treatment. Besides,…”
Get full text

A late-stage diversification via Heck-Matsuda arylation: Straightforward synthesis and cytotoxic/antiproliferative profiling of novel aryl-labdane-type derivatives by de Souza-Ferrari, Jailton, Silva-Júnior, Edvaldo Alves, Vale, Juliana Alves, de Albuquerque Simões, Luíse Araújo, de Moraes-Júnior, Manoel Oliveira, Dantas, Bruna Braga, de Araújo, Demetrius Antonio Machado

“…[Display omitted] •The labd-8(17)-en-15-oic acid 1a was isolated from Moldenhawera nutans.•A late-stage diversification of 1a via Heck-Matsuda reaction is…”
Get full text