Search Results - "Moraes, Miriam"

Synthesis and antiplasmodial activity of betulinic acid and ursolic acid analogues by Innocente, Adrine M, Silva, Gloria N S, Cruz, Laura Nogueira, Moraes, Miriam S, Nakabashi, Myna, Sonnet, Pascal, Gosmann, Grace, Garcia, Célia R S, Gnoatto, Simone C B

“…More than 40% of the World population is at risk of contracting malaria, which affects primarily poor populations in tropical and subtropical areas…”
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Bradykinin promotes murine melanoma cell migration and invasion through endogenous production of superoxide and nitric oxide by Eller-Borges, Roberta, Rodrigues, Elaine G., Teodoro, Ana Caroline S., Moraes, Miriam S., Arruda, Denise C., Paschoalin, Thaysa, Curcio, Marli F., da Costa, Paulo E., Do Nascimento, Igor R., Calixto, Leandro A., Stern, Arnold, Monteiro, Hugo P., Batista, Wagner L.

“…Spatial confinement and temporal regulation of signaling by nitric oxide (NO) and reactive oxygen species (ROS) occurs in cancer cells. Signaling mediated by…”
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Biological evaluation of hydroxynaphthoquinones as anti-malarials by Schuck, Desiree C, Ferreira, Sabrina B, Cruz, Laura N, da Rocha, David R, Moraes, Miriam S, Nakabashi, Myna, Rosenthal, Philip J, Ferreira, Vitor F, Garcia, Celia R S

“…The hydroxynaphthoquinones have been extensively investigated over the past 50 years for their anti-malarial activity. One member of this class, atovaquone, is…”
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Endothelium-derived nitric oxide (NO) activates the NO-epidermal growth factor receptor-mediated signaling pathway in bradykinin-stimulated angiogenesis by Moraes, Miriam S., Costa, Paulo E., Batista, Wagner L., Paschoalin, Taysa, Curcio, Marli F., Borges, Roberta E., Taha, Murched O., Fonseca, Fábio V., Stern, Arnold, Monteiro, Hugo P.

“…•The NO–EGF-R signaling pathway was studied in endothelial cells stimulated with bradykinin.•Bradykinin promotes tyrosine phosphorylation and cysteine…”
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Investigation of antimalarial activity, cytotoxicity and action mechanism of piperazine derivatives of betulinic acid by Silva, Gloria N. S., Schuck, Desirée C., Cruz, Laura N., Moraes, Miriam S., Nakabashi, Myna, Gosmann, Grace, Garcia, Célia R. S., Gnoatto, Simone C. B.

“…Objectives To semisynthesise piperazine derivatives of betulinic acid to evaluate antimalarial activity, cytotoxicity and action mechanism. Methods The new…”
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Plasmodium falciparum GPCR-like receptor SR25 mediates extracellular K+ sensing coupled to Ca2+ signaling and stress survival by Moraes, Miriam S., Budu, Alexandre, Singh, Maneesh K., Borges-Pereira, Lucas, Levano-Garcia, Julio, Currà, Chiara, Picci, Leonardo, Pace, Tomasino, Ponzi, Marta, Pozzan, Tullio, Garcia, Célia R. S.

“…The malaria parasite Plasmodium falciparum is exposed, during its development, to major changes of ionic composition in its surrounding medium. We demonstrate…”
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S-nitrosoglutathione and endothelial nitric oxide synthase-derived nitric oxide regulate compartmentalized ras S-nitrosylation and stimulate cell proliferation by Batista, Wagner L, Ogata, Fernando T, Curcio, Marli F, Miguel, Rodrigo B, Arai, Roberto J, Matsuo, Alisson L, Moraes, Miriam S, Stern, Arnold, Monteiro, Hugo P

“…S-nitrosylation of Cys118 is a redox-based mechanism for Ras activation mediated by nitric oxide (NO) at the plasma membrane. Ras signaling pathway stimulation…”
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Two series of new semisynthetic triterpene derivatives: differences in anti-malarial activity, cytotoxicity and mechanism of action by da Silva, Gloria N S, Maria, Nicole R G, Schuck, Desirée C, Cruz, Laura N, de Moraes, Miriam S, Nakabashi, Myna, Graebin, Cedric, Gosmann, Grace, Garcia, Célia R S, Gnoatto, Simone C B

“…The discovery and development of anti-malarial compounds of plant origin and semisynthetic derivatives thereof, such as quinine (QN) and chloroquine (CQ), has…”
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Genome-wide analysis of the human malaria parasite Plasmodium falciparum transcription factor PfNF-YB shows interaction with a CCAAT motif by Lima, Wânia Rezende, Martins, David Correa, Parreira, Kleber Simônio, Scarpelli, Pedro, Santos de Moraes, Miriam, Topalis, Pantelis, Hashimoto, Ronaldo Fumio, Garcia, Célia R S

“…Little is known about transcription factor regulation during the intraerythrocytic cycle. In order to elucidate the role of the (Pf)NF-YB transcription factor…”
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Ras, Rac1, and phosphatidylinositol-3-kinase (PI3K) signaling in nitric oxide induced endothelial cell migration by Eller-Borges, Roberta, Batista, Wagner L., da Costa, Paulo E., Tokikawa, Rita, Curcio, Marli F., Strumillo, Scheilla T., Sartori, Adriano, Moraes, Miriam S., de Oliveira, Graciele A., Taha, Murched O., Fonseca, Fábio V., Stern, Arnold, Monteiro, Hugo P.

“…•BK stimulates NO production, activates Rac and stimulates cell migration.•NO promotes the interaction between Ras and PI3K.•NO-mediated Rac activation…”
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Signaling transcript profile of the asexual intraerythrocytic development cycle of Plasmodium falciparum induced by melatonin and cAMP by Lima, Wânia Rezende, Tessarin-Almeida, Giulliana, Rozanski, Andrei, Parreira, Kleber S, Moraes, Miriam S, Martins, David C, Hashimoto, Ronaldo F, Galante, Pedro A F, Garcia, Célia R S

“…According to the World Health Organization (WHO), is the deadliest parasite among all species. This parasite possesses the ability to sense molecules,…”
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A Plasmodium falciparum MORC protein complex modulates epigenetic control of gene expression through interaction with heterochromatin by Singh, Maneesh Kumar, Bonnell, Victoria Ann, Tojal Da Silva, Israel, Santiago, Verônica Feijoli, Moraes, Miriam Santos, Adderley, Jack, Doerig, Christian, Palmisano, Giuseppe, Llinas, Manuel, Garcia, Celia R S

“…Dynamic control of gene expression is critical for blood stage development of malaria parasites. Here, we used multi-omic analyses to investigate…”
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Regulatory effects of nitric oxide on Src kinase, FAK, p130Cas, and receptor protein tyrosine phosphatase alpha (PTP-alpha): a role for the cellular redox environment by Curcio, Marli F, Batista, Wagner L, Linares, Edlaine, Nascimento, Fabio D, Moraes, Miriam S, Borges, Roberta E, Sap, Jan, Stern, Arnold, Monteiro, Hugo P

“…The role of NO in regulating the focal adhesion proteins, Src, FAK, p130 Cas, and PTP-alpha, was investigated. Fibroblasts expressing PTP-alpha (PTP-alpha(WT)…”
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The low molecular weight S-nitrosothiol, S-nitroso- N-acetylpenicillamine, promotes cell cycle progression in rabbit aortic endothelial cells by Oliveira, Carlos Jorge R., Curcio, Marli F., Moraes, Miriam S., Tsujita, Maristela, Travassos, Luiz R., Stern, Arnold, Monteiro, Hugo P.

“…S-Nitrosylation reactions are considered to be a major mechanism by which NO-related bioactivities are regulated in vivo. In the present study, we show the…”
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Protein tyrosine phosphatase alpha regulates cell detachment and cell death profiles induced by nitric oxide donors in the A431 human carcinoma cell line by da Costa, Paulo E, Batista, Wagner L, Curcio, Marli F, Moraes, Miriam S, Borges, Roberta Eller, Nascimento, Patrícia A, Travassos, Luiz R, Monteiro, Hugo P

“…We investigated the role of protein tyrosine phosphatase-alpha (PTPα) expression in the cell death profile of the A431 human carcinoma cell line that was…”
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Nicarágua e o fracasso das tentativas de revolução colorida no período de 2018 a 2023 by Joseph, Lazaro Camilo Recompensa, Moraes, Miriam Gontijo de

“…Resumo. É dever dos verdadeiros progressistas e amantes da paz desmentir e desmontar a implementação da “pós-verdade” contra a Nicaragua, isto é, desmentir as…”
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Combination of Bioactive Polymeric Membranes and Stem Cells for Periodontal Regeneration: In Vitro and In Vivo Analyses by Gonçalves, Flávia, de Moraes, Míriam Santos, Ferreira, Lorraine Braga, Carreira, Ana Cláudia Oliveira, Kossugue, Patrícia Mayumi, Boaro, Letícia Cristina Cidreira, Bentini, Ricardo, Garcia, Célia Regina da Silva, Sogayar, Mari Cleide, Arana-Chavez, Victor Elias, Catalani, Luiz Henrique

“…Regeneration of periodontal tissues requires a concerted effort to obtain consistent and predictable results in vivo. The aim of the present study was to test…”
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c-Myc protein is stabilized by fibroblast growth factor 2 and destabilized by ACTH to control cell cycle in mouse Y1 adrenocortical cells by Lepique, Ana Paula, Moraes, Miriam S, Rocha, Kátia M, Eichler, Claudia B, Hajj, Glaucia N M, Schwindt, Telma T, Armelin, Hugo A

“…ACTH is the hormone known to control adrenal cortex function and maintenance in the intact animal but, in culture, it inhibits proliferation of adrenocortical…”
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Características de comunidades de pratica existentes no Serviço de Informação em Arte: o caso da REDARTE/RJ by Melo, Elisete de Sousa, Moraes, Miriam Gontijo, Costa, Mariza Almeida

“…RESUMO O presente artigo é relato de pesquisa que busca identificar e analisar a existência das principais características de comunidades de prática na Rede de…”
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ACTH promotion of p27(Kip1) induction in mouse Y1 adrenocortical tumor cells is dependent on both PKA activation and Akt/PKB inactivation by Forti, Fábio L, Schwindt, Telma T, Moraes, Miriam S, Eichler, Claudia B, Armelin, Hugo A

“…Here we report antimitogenic mechanisms activated by the adrenocorticotropic hormone (ACTH) in the mouse Y1 adrenocortical tumor cell line. ACTH receptors…”
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