Search Results - "Moraes, Fábio Rogério"
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Cornea donation process and tissue quality for transplantation
Published in PloS one (20-04-2021)“…The quality of the corneal tissue can be influenced by several factors inherent to the recipient, donor, and to the donation and transplantation process. The…”
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Berberine associated photodynamic therapy promotes autophagy and apoptosis via ROS generation in renal carcinoma cells
Published in Biomedicine & pharmacotherapy (01-03-2020)“…[Display omitted] •Berberine associated PDT induces autophagy and apoptosis in renal carcinoma cells.•Berberine associated PDT changes target genes of…”
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Computational Biology Tools for Identifying Specific Ligand Binding Residues for Novel Agrochemical and Drug Design
Published in Current protein & peptide science (01-01-2015)“…The term "agrochemicals" is used in its generic form to represent a spectrum of pesticides, such as insecticides, fungicides or bactericides. They contain…”
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Metabolic Effects of Cobalt Ferrite Nanoparticles on Cervical Carcinoma Cells and Nontumorigenic Keratinocytes
Published in Journal of proteome research (02-12-2016)“…The cytotoxic response, cellular uptake, and metabolomic profile of HeLa and HaCaT cell lines treated with cobalt ferrite nanoparticles (CoFe2O4 NPs) were…”
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A comparison between internal protein nanoenvironments of α-helices and β-sheets
Published in PloS one (30-12-2020)“…Secondary structure elements are generally found in almost all protein structures revealed so far. In general, there are more β-sheets than α helices found…”
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Potential new biocatalysts for biofuel production: The fungal lipases of Thermomyces lanuginosus and Rhizomucor miehei immobilized on zeolitic supports ion exchanged with transition metals
Published in Microporous and mesoporous materials (15-09-2015)“…Nanozeolite NaX ion exchanged with different transition metals (Mn2+,Cu2+, Co2+, Zn2+, Ni2+) was used as a solid support for the immobilization of the lipases…”
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Comparative Biochemical, Structural, and Functional Analysis of Recombinant Phospholipases D from Three Loxosceles Spider Venoms
Published in International journal of molecular sciences (26-07-2023)“…Spiders of genus are widely distributed and their venoms contain phospholipases D (PLDs), which degrade phospholipids and trigger inflammatory responses,…”
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Staphylococcus aureus Exfoliative Toxin E, Oligomeric State and Flip of P186: Implications for Its Action Mechanism
Published in International journal of molecular sciences (01-09-2022)“…Staphylococcal exfoliative toxins (ETs) are glutamyl endopeptidases that specifically cleave the Glu381-Gly382 bond in the ectodomains of desmoglein 1 (Dsg1)…”
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Brown Spider Venom Phospholipase-D Activity upon Different Lipid Substrates
Published in Toxins (27-01-2023)“…Brown spider envenomation results in dermonecrosis, characterized by an intense inflammatory reaction. The principal toxins of brown spider venoms are…”
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Potential Implications for Designing Drugs Against the Brown Spider Venom Phospholipase‐D
Published in Journal of cellular biochemistry (01-04-2017)“…ABSTRACT Loxoscelism refers to the clinical symptoms that develop after brown spider bites. Brown spider venoms contain several phospholipase‐D isoforms, which…”
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Comparative Biochemical, Structural, and Functional Analysis of Recombinant Phospholipases D from Three ILoxosceles/I Spider Venoms
Published in International journal of molecular sciences (01-07-2023)“…Spiders of Loxosceles genus are widely distributed and their venoms contain phospholipases D (PLDs), which degrade phospholipids and trigger inflammatory…”
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The Secreted Metabolome of Hela Cells under Effect of Crotamine, a Cell-Penetrating Peptide from a Rattlesnake Using NMR-Based Metabolomics Analyses
Published in BioMed (22-04-2022)“…Sequestering and reprogramming of cellular metabolism represents one of the principal hallmarks of several cells. Antimicrobial peptides have been shown to…”
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Phospholipase D from venoms of Loxosceles spiders: a structural, biochemical and biological comparison
Published in Toxicon (Oxford) (05-10-2019)Get full text
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Recent advances in the understanding of brown spider venoms: From the biology of spiders to the molecular mechanisms of toxins
Published in Toxicon (Oxford) (01-06-2014)“…The Loxosceles genus spiders (the brown spiders) are encountered in all the continents, and the clinical manifestations following spider bites include skin…”
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Thermodynamic analysis of interactions of the Hsp90 with adenosine nucleotides: A comparative perspective
Published in International journal of biological macromolecules (01-06-2019)“…Hsp90s are key proteins in cellular homeostasis since they interact with many client proteins. Several studies indicated that Hsp90s are potential targets for…”
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In silico evaluation of natural compounds to confirm their anti-DNA gyrase activity
Published in Nucleus (Calcutta) (01-08-2023)“…The slow clearance of bacteria owing to drug resistance to the currently available antibiotics has been a global public health issue. The development of…”
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Protein allosteric site identification using machine learning and per amino acid residue reported internal protein nanoenvironment descriptors
Published in Computational and structural biotechnology journal (01-12-2024)“…Allosteric regulation plays a crucial role in modulating protein functions and represents a promising strategy in drug development, offering enhanced…”
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Identification of Folding Intermediates of Streblin, The Most Stable Serine Protease: Biophysical Analysis
Published in Applied biochemistry and biotechnology (01-01-2014)“…Streblin, a serine proteinase from plant Streblus asper, has been used to investigate the conformational changes induced by pH, temperature, and chaotropes…”
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