Search Results - "Moraes, Daniel Clemente"
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Multidrug-Resistant Fungi
Published in Journal of fungi (Basel) (30-09-2024)“…Multidrug resistance in fungi is a growing challenge to global public health, resulting in ineffective treatments and thus high mortality rates [...]…”
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Dentine biomodification by sulphonamides pre-treatment: bond strength, proteolytic inhibition, and antimicrobial activity
Published in Journal of enzyme inhibition and medicinal chemistry (01-12-2023)“…We evaluated the effects of dentine biomodification after pre-treatment with two sulphonamide carbonic anhydrase inhibitors (CAIs) of the…”
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3
Casearia sylvestris essential oil and its fractions inhibit Candida albicans ABC transporters related to multidrug resistance (MDR)
Published in Rodriguésia (2021)“…Abstract ABC transporters constitute a superfamily of transmembrane proteins that act mediating the translocation of several substrates across the membrane,…”
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Synthesis of Altissimacoumarin D and Other Prenylated Coumarins and Their Ability to Reverse the Multidrug Resistance Phenotype in Candida albicans
Published in Journal of fungi (Basel) (18-07-2023)“…Azoles are the main antifungal agents employed in clinical practice to treat invasive candidiasis. Nonetheless, their efficacy is limited by fungal resistance…”
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Digoxin Derivatives Sensitize a Saccharomyces cerevisiae Mutant Strain to Fluconazole by Inhibiting Pdr5p
Published in Journal of fungi (Basel) (25-07-2022)“…The poor outcome of treatments for fungal infections is a consequence of the increasing incidence of resistance to antifungal agents, mainly due to the…”
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Structural and Functional Alterations Caused by Aureobasidin A in Clinical Resistant Strains of Candida spp
Published in Journal of fungi (Basel) (01-11-2023)“…Candida species are one of the most concerning causative agents of fungal infections in humans. The treatment of invasive Candida infections is based on the…”
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Antifungal activity of β-lapachone against a fluconazole-resistant Candida auris strain
Published in Brazilian journal of microbiology (01-09-2024)“…Candida spp. can be found in the human microbiome. However, immunocompromised patients are likely to develop invasive Candida infections, with mortality rates…”
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β-Lapachone enhances the antifungal activity of fluconazole against a Pdr5p-mediated resistant Saccharomyces cerevisiae strain
Published in Brazilian journal of microbiology (01-09-2020)“…Objectives The aim of this study was to evaluate the ability of lapachones in disrupting the fungal multidrug resistance (MDR) phenotype, using a model of…”
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Effects of β-lapachone and β-nor-lapachone on multidrug efflux transporters and biofilms of Candida glabrata
Published in Bioorganic & medicinal chemistry (01-06-2022)“…[Display omitted] Infections caused particularly by Candida glabrata are hard to treat due to the development of antifungal resistance that occurs mainly…”
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Salivary pH and colonization by oral Candida in children and adolescents submitted to haemodialysis
Published in International journal of paediatric dentistry (01-09-2018)“…Background Fungal infections are a serious problem among haemodialysis patients. Aim The aims of this study were to estimate the frequency of oral Candida…”
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Current scenario of the search for new antifungal agents to treat Candida auris infections: An integrative review
Published in Journal de mycologie médicale (01-03-2022)“…Candida auris emerges as an important causative agent of fungal infections, with worrisome mortality rates, mainly in immunocompromised individuals. This…”
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Recent developments on the anti-Candida effect of amphotericin B combined with a second drug - a mini-review
Published in Anais da Academia Brasileira de Ciências (01-01-2023)“…Invasive Candida infections threaten human health due to the increasing incidence of resistance to the currently available antifungal agents. Amphotericin B…”
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Salivary proteins modulate Candida albicans virulence and may prevent oropharingeal candidiasis
Published in Brazilian journal of microbiology (25-09-2024)“…Oral candidiasis can be presented in different ways due to the virulence factors of its etiology such as Candida albicans that have developed an effective set…”
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Synthesis of Altissimacoumarin D and Other Prenylated Coumarins and Their Ability to Reverse the Multidrug Resistance Phenotype in ICandida albicans/I
Published in Journal of fungi (Basel) (01-07-2023)“…Azoles are the main antifungal agents employed in clinical practice to treat invasive candidiasis. Nonetheless, their efficacy is limited by fungal resistance…”
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15
Structural and Functional Alterations Caused by Aureobasidin A in Clinical Resistant Strains of ICandida/I spp
Published in Journal of fungi (Basel) (01-11-2023)“…Candida species are one of the most concerning causative agents of fungal infections in humans. The treatment of invasive Candida infections is based on the…”
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Synergistic interactions between β-lapachone and fluconazole in the inhibition of CaCdr2p and CaMdr1p in Candida albicans
Published in Revista iberoamericana de micología (01-07-2020)“…Mortality rate of invasive Candida infections is raising mainly amongst immunocompromised patients. These infections are hard-to-treat mainly due to the…”
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