Search Results - "Moradzadeh, Maliheh"
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Epigallocatechin-3-gallate promotes apoptosis in human breast cancer T47D cells through down-regulation of PI3K/AKT and Telomerase
Published in Pharmacological reports (01-10-2017)“…Green tea has antioxidant, anti-tumor and anti-bacterial properties. Epigallocatechin-3-gallate (EGCG) in green tea is highly active as a cancer…”
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Kaempferol increases apoptosis in human acute promyelocytic leukemia cells and inhibits multidrug resistance genes
Published in Journal of cellular biochemistry (01-02-2018)“…Acute promyelocytic leukemia (APL) is one of the most life‐threatening hematological malignancies. Defects in the cell growth and apoptotic pathways are…”
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Efficacy and safety of rituximab therapy in patients with systemic sclerosis disease (SSc): systematic review and meta-analysis
Published in Clinical rheumatology (01-10-2021)“…The clinical benefits of rituximab in systemic sclerosis (SSc) are still contentious. The present meta-analysis aimed to systematically assess rituximab’s…”
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A comparative study of anti-leukemic effects of kaempferol and epigallocatechin-3-gallate (EGCG) on human leukemia HL-60 cells
Published in Avicenna journal of phytomedicine (01-07-2021)“…OBJECTIVEAcute promyelocytic leukemia (APL) is among the most threatening hematological malignant cancers. Defects in cell growth and apoptotic pathways lead…”
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A rebuttal letter to the letter ID number CLRH-D-21–00,836 entitled “On the efficacy and safety of rituximab therapy in patients with systemic sclerosis disease: missing points, bottlenecks, over-exaggeration and discrepancies”
Published in Clinical rheumatology (01-11-2021)Get full text
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Janerin, a Sesquiterpene Lactone, Enhances the Apoptosis of Human Leukemia Cell Lines via the Intrinsic Pathway
Published in Journal of chemistry (22-07-2024)“…Background . Still, cancer remains to be one of the main causes of death globally. Sesquiterpene lactones (SLs) appeared to have remarkable pharmacologic…”
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Ferula gummosa gum induces apoptosis via ROS mechanism in human leukemic cells
Published in Cellular and Molecular Biology (30-11-2017)“…Ferula species known for its oleo-resins that are recognized valuable industrial crops and food products. In this study, we examined the level of cellular…”
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Crocin Promotes Apoptosis in Human EBV-Transformed B-Lymphocyte via Intrinsic Pathway
Published in Mediterranean journal of hematology and infectious diseases (01-07-2021)“…As a major carotenoid in saffron, crocin demonstrates potent anti-cancer impacts. However, its anti-lymphoma effects remain vague, especially in the human…”
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Hereditary Nonpolyposis Colorectal Cancer (HNPCC)/Lynch Syndrome: Surveillance and Diagnostic strategies
Published in Majallah-i dānishgāh-i ̕ulūm-i pizishkī va khadamāt-i bihdāshtī-darmānī Shahīd Ṣadūqī Yazd (26-04-2021)“…Introduction: Hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) is an autosomal dominant genetic disease. The disease is caused by a mutation…”
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Hamartomatous Polyposis Syndromes: Management and Surveillance Strategies
Published in Majallah-i dānishgāh-i ̕ulūm-i pizishkī va khadamāt-i bihdāshtī-darmānī Shahīd Ṣadūqī Yazd (08-09-2020)“…Introduction: Hamartomatous Polyposis Syndromes (HPS) are a rare group of dominant autosomal inheritance, which is characterized by the development of…”
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Therapeutic Potency of PI3K Pharmacological Inhibitors of Gastrointestinal Cancer
Published in Middle East journal of digestive diseases (01-01-2019)“…Therapeutic targeting of phosphatidyl-inositol 3-kinase (PI3K) is considered as a possible strategy in several types of cancer, including gastrointestinal…”
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Rheum turkestanicum reduces glutamate toxicity in PC12 and N2a cell lines
Published in Folia neuropathologica (01-01-2018)“…Glutamate is considered to be responsible for the pathogenesis of many neurodegenerative diseases. Reactive oxygen species (ROS) production is considered to be…”
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Effects of standardized extract of Ferula gummosa root on glutamate-induced neurotoxicity
Published in Folia neuropathologica (01-01-2017)“…Glutamate is one of the major excitatory neurotransmitters in the central nervous system. Increasing glutamate leads to neurodegenerative disease. Nowadays,…”
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Cuscuta campestris induces apoptosis by increasing reactive oxygen species generation in human leukemic cells
Published in Avicenna journal of phytomedicine (01-05-2018)“…or common dodder is a holoparasitic plant that has been valorized for treatment of liver injury and cancer prevention in traditional medicine. Recently,…”
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An Increased Level of Aryl Hydrocarbon Receptor in Patients with Pancreatic Cancer
Published in Middle East journal of digestive diseases (01-01-2019)“…BACKGROUND Aryl-carbon receptor (AhR), a ligand-activated transcription factor, is best known for its ability to mediate the effects of environmental toxins…”
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The antileukemic effects of saffron (Crocus sativus L.) and its related molecular targets: A mini review
Published in Journal of cellular biochemistry (01-04-2019)“…Saffron (Crocus sativus L.), and its main constituents, crocin, and crocetin have shown promising effects as an antileukemic agent in animal models and cell…”
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Kaempferol increases apoptosis in human cervical cancer HeLa cells via PI3K/AKT and telomerase pathways
Published in Biomedicine & pharmacotherapy (01-05-2017)“…Graphical abstract…”
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Anti‐tumor effects of crocetin and related molecular targets
Published in Journal of cellular physiology (01-03-2018)“…Natural products have gained a wide popularity as chemopreventive and anti‐cancer agents owing to their multi‐mechanistic mode of action, availability and…”
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Epigallocatechin‐3‐gallate enhances differentiation of acute promyelocytic leukemia cells via inhibition of PML‐RARα and HDAC1
Published in Phytotherapy research (01-03-2018)“…The use of all‐trans retinoic acid (ATRA) has dramatically improved the treatment and survival rate of patients with acute promyelocytic leukemia (APL)…”
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Inflammation, diet, and type 2 diabetes: a mini-review
Published in Journal of immunoassay & immunochemistry (03-07-2020)“…Inflammation is a common feature of type 2 diabetes (T2D). Inflammatory cytokines increase in patients with type 2 diabetes, metabolic syndrome, and heart…”
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