Search Results - "Moradi Kashkooli, Farshad"
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1
Evaluation of solid tumor response to sequential treatment cycles via a new computational hybrid approach
Published in Scientific reports (02-11-2021)“…The development of an in silico approach that evaluates and identifies appropriate treatment protocols for individuals could help grow personalized treatment…”
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Effects of hypoxia and nanocarrier size on pH-responsive nano-delivery system to solid tumors
Published in Scientific reports (29-09-2021)“…One of the special features of solid tumors is the acidity of the tumor microenvironment, which is mainly due to the presence of hypoxic regions. Therefore,…”
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3
Computational modeling of thermal combination therapies by magneto-ultrasonic heating to enhance drug delivery to solid tumors
Published in Scientific reports (01-10-2021)“…For the first time, inspired by magnetic resonance imaging-guidance high intensity focused ultrasound (MR-HIFU) technology, i.e. , medication therapy and…”
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4
Analysis of Magneto-Hyperthermia Duration in Nano-sized Drug Delivery System to Solid Tumors Using Intravascular-Triggered Thermosensitive-Liposome
Published in Pharmaceutical research (01-04-2022)“…Computational models have been developed as a potential platform to identify bio-interactions that cannot be properly understood by experimental models. In the…”
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5
Optimization and energy-economic assessment of a geothermal heat pump system
Published in Renewable & sustainable energy reviews (01-11-2020)“…The high geothermal heat exchanger (GHE) installation cost is the main challenge encountered in the widespread use of geothermal heat pump (GHP) systems, so…”
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A comparative study between conventional chemotherapy and photothermal activated nano-sized targeted drug delivery to solid tumor
Published in Computers in biology and medicine (01-11-2023)“…Delivery of chemotherapeutic medicines to solid tumors is critical for optimal therapeutic success and minimal adverse effects. We mathematically developed a…”
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A spatiotemporal computational model of focused ultrasound heat-induced nano-sized drug delivery system in solid tumors
Published in Drug delivery (01-12-2023)“…Focused Ultrasound (FUS)-triggered nano-sized drug delivery, as a smart stimuli-responsive system for treating solid tumors, is computationally investigated to…”
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Spatiotemporal multi-scale modeling of radiopharmaceutical distributions in vascularized solid tumors
Published in Scientific reports (26-08-2022)“…We present comprehensive mathematical modeling of radiopharmaceutical spatiotemporal distributions within vascularized solid tumors. The novelty of the…”
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9
Synthetic 18F-FDG PET Image Generation Using a Combination of Biomathematical Modeling and Machine Learning
Published in Cancers (03-06-2022)“…No previous works have attempted to combine generative adversarial network (GAN) architectures and the biomathematical modeling of positron emission tomography…”
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Towards principled design of cancer nanomedicine to accelerate clinical translation
Published in Materials today bio (01-01-2022)“…Nanotechnology in medical applications, especially in oncology as drug delivery systems, has recently shown promising results. However, although these advances…”
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Ultrasound‐mediated nano‐sized drug delivery systems for cancer treatment: Multi‐scale and multi‐physics computational modeling
Published in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology (01-01-2024)“…Computational modeling enables researchers to study and understand various complex biological phenomena in anticancer drug delivery systems (DDSs), especially…”
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Enhancing Clinical Translation of Cancer Using Nanoinformatics
Published in Cancers (19-05-2021)“…Application of drugs in high doses has been required due to the limitations of no specificity, short circulation half-lives, as well as low bioavailability and…”
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Effect of tumor heterogeneity on enhancing drug delivery to vascularized tumors using thermo-sensitive liposomes triggered by hyperthermia: A multi-scale and multi-physics computational model
Published in Computers in biology and medicine (01-03-2024)“…In this study, a novel multi-scale and multi-physics image-based computational model is introduced to assess the delivery of doxorubicin (Dox) loaded…”
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14
Fluid Flow and Heat Transfer Analysis of a Nanofluid Containing Motile Gyrotactic Micro-Organisms Passing a Nonlinear Stretching Vertical Sheet in the Presence of a Non-Uniform Magnetic Field; Numerical Approach
Published in PloS one (20-06-2016)“…The behavior of a water-based nanofluid containing motile gyrotactic micro-organisms passing an isothermal nonlinear stretching sheet in the presence of a…”
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15
Optimal design of plate-fin heat exchangers by a Bees Algorithm
Published in Applied thermal engineering (01-08-2014)“…In this study, the application of Bees Algorithm (BA) in the optimum design of a cross flow plate-fin heat exchanger with offset strip fin is investigated…”
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16
Effect of Upstream Side Flow of Wind Turbine on Aerodynamic Noise: Simulation Using Open-Loop Vibration in the Rod in Rod-Airfoil Configuration
Published in Energies (Basel) (01-02-2021)“…Adaptive and flexible control techniques have recently been examined as methods of controlling flow and reducing the potential noise in vertical axis wind…”
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Computational Modeling of Combination of Magnetic Hyperthermia and Temperature-Sensitive Liposome for Controlled Drug Release in Solid Tumor
Published in Pharmaceutics (24-12-2021)“…Combination therapy, a treatment modality that combines two or more therapeutic methods, provides a novel pathway for cancer treatment, as it targets the…”
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Improving Energy Efficiency by Utilizing Wetted Cellulose Pads in Passive Cooling Systems
Published in Energies (Basel) (01-01-2022)“…The effectiveness of using wetted cellulose pads on improving the performance of two conventional passive cooling systems has been evaluated. First, an…”
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Controlled anti-cancer drug release through advanced nano-drug delivery systems: Static and dynamic targeting strategies
Published in Journal of controlled release (10-11-2020)“…Advances in nanomedicine, including early cancer detection, targeted drug delivery, and personalized approaches to cancer treatment are on the rise. For…”
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Integrating Therapeutic Ultrasound With Nanosized Drug Delivery Systems in the Battle Against Cancer
Published in Technology in Cancer Research & Treatment (01-01-2023)“…Controlled, localized, and timely activation of nanosized drug delivery systems (NSDDSs), using an external stimulus such as therapeutic ultrasound (TUS), can…”
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