Search Results - "Moradi Chameh, Homeira"

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  1. 1

    Diversity amongst human cortical pyramidal neurons revealed via their sag currents and frequency preferences by Moradi Chameh, Homeira, Rich, Scott, Wang, Lihua, Chen, Fu-Der, Zhang, Liang, Carlen, Peter L., Tripathy, Shreejoy J., Valiante, Taufik A.

    Published in Nature communications (03-05-2021)
    “…In the human neocortex coherent interlaminar theta oscillations are driven by deep cortical layers, suggesting neurons in these layers exhibit distinct…”
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  2. 2

    Brief activation of GABAergic interneurons initiates the transition to ictal events through post-inhibitory rebound excitation by Chang, Michael, Dian, Joshua A., Dufour, Suzie, Wang, Lihua, Moradi Chameh, Homeira, Ramani, Meera, Zhang, Liang, Carlen, Peter L., Womelsdorf, Thilo, Valiante, Taufik A.

    Published in Neurobiology of disease (01-01-2018)
    “…Activation of γ-aminobutyric acid (GABAA) receptors have been associated with the onset of epileptiform events. To investigate if a causal relationship exists…”
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  3. 3

    Reduced inhibition in depression impairs stimulus processing in human cortical microcircuits by Yao, Heng Kang, Guet-McCreight, Alexandre, Mazza, Frank, Moradi Chameh, Homeira, Prevot, Thomas D., Griffiths, John D., Tripathy, Shreejoy J., Valiante, Taufik A., Sibille, Etienne, Hay, Etay

    Published in Cell reports (Cambridge) (11-01-2022)
    “…Cortical processing depends on finely tuned excitatory and inhibitory connections in neuronal microcircuits. Reduced inhibition by somatostatin-expressing…”
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    Effect of low frequency repetitive transcranial magnetic stimulation on kindling-induced changes in electrophysiological properties of rat CA1 pyramidal neurons by Moradi Chameh, Homeira, Janahmadi, Mahyar, Semnanian, Saeed, Shojaei, Amir, Mirnajafi-Zadeh, Javad

    Published in Brain research (05-05-2015)
    “…Abstract In this study, the effect of repetitive transcranial magnetic stimulation (rTMS) on the kindling induced changes in electrophysiological firing…”
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  6. 6

    Loss of neuronal heterogeneity in epileptogenic human tissue impairs network resilience to sudden changes in synchrony by Rich, Scott, Moradi Chameh, Homeira, Lefebvre, Jeremie, Valiante, Taufik A.

    Published in Cell reports (Cambridge) (24-05-2022)
    “…A myriad of pathological changes associated with epilepsy can be recast as decreases in cell and circuit heterogeneity. We thus propose recontextualizing…”
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  7. 7

    Regulating hippocampal hyperexcitability through GABAB Receptors by Lang, Min, MoradiChameh, Homeira, Zahid, Tariq, Gane, Jonathan, Wu, Chiping, Valiante, Taufik, Zhang, Liang

    Published in Physiological reports (01-04-2014)
    “…Disturbances of GABAergic inhibition are a major cause of epileptic seizures. GABA exerts its actions via ionotropic GABAA receptors and metabotropic G…”
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    Modeling Reveals Human–Rodent Differences in H-Current Kinetics Influencing Resonance in Cortical Layer 5 Neurons by Rich, Scott, Moradi Chameh, Homeira, Sekulic, Vladislav, Valiante, Taufik A, Skinner, Frances K

    Published in Cerebral cortex (New York, N.Y. 1991) (05-01-2021)
    “…Abstract While our understanding of human neurons is often inferred from rodent data, inter-species differences between neurons can be captured by building…”
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  10. 10

    Fingolimod Administration Following Hypoxia Induced Neonatal Seizure Can Restore Impaired Long-term Potentiation and Memory Performance in Adult Rats by Hajipour, Somayeh, Khombi Shooshtari, Maryam, Farbood, Yaghoob, Ali Mard, Seyed, Sarkaki, Alireza, Moradi Chameh, Homeira, Sistani Karampour, Neda, Ghafouri, Samireh

    Published in Neuroscience (21-05-2023)
    “…•FTY720 administration following HINS could restore the dysregulated gene expression of excitatory and inhibitory receptors.•FTY720 administration following…”
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  11. 11

    Inhibitory Network Bistability Explains Increased Interneuronal Activity Prior to Seizure Onset by Rich, Scott, Chameh, Homeira Moradi, Rafiee, Marjan, Ferguson, Katie, Skinner, Frances K, Valiante, Taufik A

    Published in Frontiers in neural circuits (14-01-2020)
    “…Recent experimental literature has revealed that GABAergic interneurons exhibit increased activity prior to seizure onset, alongside additional evidence that…”
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  12. 12

    Hyperpolarization-activated cation channels shape the spiking frequency preference of human cortical layer 5 pyramidal neurons by Inibhunu, Happy, Moradi Chameh, Homeira, Skinner, Frances K, Rich, Scott, Valiante, Taufik A

    Published in eNeuro (01-08-2023)
    “…Discerning the contribution of specific ionic currents to complex neuronal dynamics is a difficult, but important, task. This challenge is exacerbated in the…”
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  13. 13

    Distinctive biophysical features of human cell-types: insights from studies of neurosurgically resected brain tissue by Chameh, Homeira Moradi, Falby, Madeleine, Movahed, Mandana, Arbabi, Keon, Rich, Scott, Zhang, Liang, Lefebvre, Jérémie, Tripathy, Shreejoy J., De Pittà, Maurizio, Valiante, Taufik A.

    Published in Frontiers in synaptic neuroscience (04-10-2023)
    “…Electrophysiological characterization of live human tissue from epilepsy patients has been performed for many decades. Although initially these studies sought…”
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    An in vitro whole-cell electrophysiology dataset of human cortical neurons by Howard, Derek, Chameh, Homeira Moradi, Guet-McCreight, Alexandre, Hsiao, Huan Allen, Vuong, Maggie, Seo, Young Seok, Shah, Prajay, Nigam, Anukrati, Chen, Yuxiao, Davie, Melanie, Hay, Etay, Valiante, Taufik A, Tripathy, Shreejoy J

    Published in Gigascience (15-11-2022)
    “…Abstract Background Whole-cell patch-clamp electrophysiology is an essential technique for understanding how single neurons translate their diverse inputs into…”
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  16. 16

    In-silico testing of new pharmacology for restoring inhibition and human cortical function in depression by Guet-McCreight, Alexandre, Chameh, Homeira Moradi, Mazza, Frank, Prevot, Thomas D., Valiante, Taufik A., Sibille, Etienne, Hay, Etay

    Published in Communications biology (23-02-2024)
    “…Reduced inhibition by somatostatin-expressing interneurons is associated with depression. Administration of positive allosteric modulators of α5…”
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  17. 17

    Author Correction: A community-based transcriptomics classification and nomenclature of neocortical cell types by Yuste, Rafael, Hawrylycz, Michael, Aalling, Nadia, Aguilar-Valles, Argel, Arendt, Detlev, Armañanzas, Ruben, Ascoli, Giorgio A., Bielza, Concha, Bokharaie, Vahid, Bergmann, Tobias Borgtoft, Bystron, Irina, Capogna, Marco, Chang, YoonJeung, Clemens, Ann, de Kock, Christiaan P. J., DeFelipe, Javier, Dos Santos, Sandra Esmeralda, Dunville, Keagan, Feldmeyer, Dirk, Fiáth, Richárd, Fishell, Gordon James, Foggetti, Angelica, Gao, Xuefan, Ghaderi, Parviz, Goriounova, Natalia A., Güntürkün, Onur, Hagihara, Kenta, Hall, Vanessa Jane, Helmstaedter, Moritz, Herculano-Houzel, Suzana, Hilscher, Markus M., Hirase, Hajime, Hjerling-Leffler, Jens, Hodge, Rebecca, Huang, Josh, Huda, Rafiq, Khodosevich, Konstantin, Kiehn, Ole, Koch, Henner, Kuebler, Eric S., Kühnemund, Malte, Larrañaga, Pedro, Lelieveldt, Boudewijn, Louth, Emma Louise, Lui, Jan H., Mansvelder, Huibert D., Marin, Oscar, Martinez-Trujillo, Julio, Chameh, Homeira Moradi, Mohapatra, Alok Nath, Munguba, Hermany, Nedergaard, Maiken, Němec, Pavel, Ofer, Netanel, Pfisterer, Ulrich Gottfried, Pontes, Samuel, Redmond, William, Rossier, Jean, Sanes, Joshua R., Scheuermann, Richard H., Serrano-Saiz, Esther, Staiger, Jochen F., Somogyi, Peter, Tamás, Gábor, Tolias, Andreas Savas, Tosches, Maria Antonietta, García, Miguel Turrero, Wozny, Christian, Wuttke, Thomas V., Liu, Yong, Yuan, Juan, Zeng, Hongkui, Lein, Ed

    Published in Nature neuroscience (01-04-2021)
    “…A Correction to this paper has been published: https://doi.org/10.1038/s41593-020-00779-0…”
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  18. 18

    Age-dependent increased sag amplitude in human pyramidal neurons dampens baseline cortical activity by Guet-McCreight, Alexandre, Chameh, Homeira Moradi, Mahallati, Sara, Wishart, Margaret, Tripathy, Shreejoy J, Valiante, Taufik A, Hay, Etay

    Published in Cerebral cortex (New York, N.Y. 1991) (04-04-2023)
    “…Abstract Aging involves various neurobiological changes, although their effect on brain function in humans remains poorly understood. The growing availability…”
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  19. 19

    A community-based transcriptomics classification and nomenclature of neocortical cell types by Yuste, Rafael, Hawrylycz, Michael, Aalling, Nadia, Aguilar-Valles, Argel, Arendt, Detlev, Armañanzas, Ruben, Ascoli, Giorgio A., Bielza, Concha, Bokharaie, Vahid, Bergmann, Tobias Borgtoft, Bystron, Irina, Capogna, Marco, Chang, YoonJeung, Clemens, Ann, de Kock, Christiaan P. J., DeFelipe, Javier, Dos Santos, Sandra Esmeralda, Dunville, Keagan, Feldmeyer, Dirk, Fiáth, Richárd, Fishell, Gordon James, Foggetti, Angelica, Gao, Xuefan, Ghaderi, Parviz, Goriounova, Natalia A., Güntürkün, Onur, Hagihara, Kenta, Hall, Vanessa Jane, Helmstaedter, Moritz, Herculano-Houzel, Suzana, Hilscher, Markus M., Hirase, Hajime, Hjerling-Leffler, Jens, Hodge, Rebecca, Huang, Josh, Huda, Rafiq, Khodosevich, Konstantin, Kiehn, Ole, Koch, Henner, Kuebler, Eric S., Kühnemund, Malte, Larrañaga, Pedro, Lelieveldt, Boudewijn, Louth, Emma Louise, Lui, Jan H., Mansvelder, Huibert D., Marin, Oscar, Martinez-Trujillo, Julio, Chameh, Homeira Moradi, Mohapatra, Alok Nath, Munguba, Hermany, Nedergaard, Maiken, Němec, Pavel, Ofer, Netanel, Pfisterer, Ulrich Gottfried, Pontes, Samuel, Redmond, William, Rossier, Jean, Sanes, Joshua R., Scheuermann, Richard H., Serrano-Saiz, Esther, Staiger, Jochen F., Somogyi, Peter, Tamás, Gábor, Tolias, Andreas Savas, Tosches, Maria Antonietta, García, Miguel Turrero, Wozny, Christian, Wuttke, Thomas V., Liu, Yong, Yuan, Juan, Zeng, Hongkui, Lein, Ed

    Published in Nature neuroscience (01-12-2020)
    “…To understand the function of cortical circuits, it is necessary to catalog their cellular diversity. Past attempts to do so using anatomical, physiological or…”
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    Anticonvulsive effects of endocannabinoids; an investigation to determine the role of regulatory components of endocannabinoid metabolism in the Pentylenetetrazol induced tonic- clonic seizures by Zareie, Parisa, Sadegh, Mehdi, Palizvan, Mohammad Reza, Moradi-Chameh, Homeira

    Published in Metabolic brain disease (01-06-2018)
    “…2-Arachidonoylglycerol (2-AG) and anandamide are two major endocannabinoids produced, released and eliminated by metabolic pathways. Anticonvulsive effect of…”
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