Search Results - "Morán, Joaquín R"
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5‑Chloro-8-nitro-1-naphthoyl (NNap): A Selective Protective Group for Amines and Amino Acids
Published in Organic letters (09-06-2023)“…The synthesis of 5-chloro-8-nitro-1-naphthoyl chloride and its use as a protective group for amines is described. Protection is carried out with an auxiliary…”
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2
Highly Enantioselective Extraction of Phenylglycine by a Chiral Macrocyclic Receptor Based on Supramolecular Interactions
Published in Organic letters (07-02-2020)“…Using supramolecular interactions, a novel macrocyclic receptor is able to selectively extract zwitterionic phenylglycine from neutral aqueous solutions into…”
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3
Transesterification of Non‐Activated Esters Promoted by Small Molecules Mimicking the Active Site of Hydrolases
Published in Angewandte Chemie International Edition (26-08-2022)“…The synthesis of small molecules able to mimic the active site of hydrolytic enzymes has been largely pursued in recent decades. The high reaction rates and…”
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4
An Enzyme Model Which Mimics Chymotrypsin and N‑Terminal Hydrolases
Published in ACS catalysis (02-10-2020)“…Enzymes are the most efficient and specific catalysts to date. Although they have been thoroughly studied for years, building a true enzyme mimic remains a…”
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5
An Adjustable Cleft Based on an 8‐Sulfonamide‐2‐Naphthoic Acid with Oxyanion Hole Geometry
Published in Chemistry : a European journal (21-10-2021)“…Cleft type receptors showing the oxyanion hole motif have been prepared in a straightforward synthesis starting from the commercial 3,7‐dihidroxy‐2‐naphthoic…”
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6
A molecular receptor selective for zwitterionic alanine
Published in Organic & biomolecular chemistry (2017)“…A molecular receptor has been synthesized joining an aza-crown ether with a chiral chromane which mimics the oxyanion hole of the enzymes. With this receptor…”
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7
Synthesis of Monoacylated Derivatives of 1,2- Cyclohexanediamine. Evaluation of their Catalytic Activity in the Preparation of Wieland−Miescher Ketone
Published in Journal of organic chemistry (03-12-2010)“…Ureas, carbamoyl derivatives, amides, and sulfonamides can be easily prepared from the strained (R,R)-cylohexanediamine urea (1) in high yield, leaving a free…”
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Bifunctional organocatalysts based on a carbazole scaffold for the synthesis of the Hajos–Wiechert and Wieland–Miescher ketones
Published in Tetrahedron (25-02-2015)“…Several bifunctional organocatalysts based on a carbazole scaffold containing a chiral amine and a synthetic oxyanion-hole have been synthesized and…”
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9
A bio-inspired enantioselective small-molecule artificial receptor for β adrenergic agonists and antagonists and its application for enantioselective extraction
Published in Chemical communications (Cambridge, England) (01-01-2016)“…Administration of enantiomerically pure β-adrenergic agonists and antagonists increases their activity and reduces side effects. We report here a…”
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10
A molecular receptor for zwitterionic phenylalanine
Published in Organic & biomolecular chemistry (28-04-2016)“…The combination of a 1,3-ketoenol system and two pyridine molecules attached as sulfonamide and carboxamide to a benzofuran skeleton allows the preparation of…”
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Chiral recognition with a benzofuran receptor that mimics an oxyanion hole
Published in Organic & biomolecular chemistry (14-01-2015)“…A new chiral benzofuran receptor has been synthesized and its properties in the association of amino acid derivatives have been studied. X-ray structures were…”
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12
Proline imidazolidinones and enamines in Hajos–Wiechert and Wieland–Miescher ketone synthesis
Published in Tetrahedron (20-06-2009)“…Readily available aromatic prolinamides obtained from the acid chloride of proline hydrochloride and anilines induce large enantiomeric excesses in…”
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13
A highly selective receptor for zwitterionic proline
Published in Organic & biomolecular chemistry (01-01-2016)“…A chiral chromane receptor has been synthesized which mimics the oxyanion hole of the enzymes. In this receptor H-bonds and cation-π interactions team up to…”
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14
Sulfonamide carbazole receptors for anion recognition
Published in Organic & biomolecular chemistry (21-12-2011)“…Carbazole-based receptors functionalized with two sulfonamide groups have been synthesized and their properties as anion receptors have been evaluated. The…”
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15
A High Yield Procedure for the Preparation of 2-Hydroxynitrostyrenes: Synthesis of Imines and Tetracyclic 1,3-Benzoxazines
Published in European journal of organic chemistry (01-05-2014)“…Attempts to synthesize 2‐hydroxynitrostyrenes by a Knoevenagel condensation of salicylaldehyde and subsequent elimination were unsuccessful because of the…”
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16
Preparation of cyclic boramides from salicylaldehydes, ammonium acetate and sodium borohydride
Published in Tetrahedron (11-11-2014)“…Borohydride reduction of salicylaldehyde imines yields surprisingly a cyclic boramide. This is a fairly stable compound, and X-ray analysis shows it has a…”
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17
Macrocyclic Chiral Receptors toward Enantioselective Recognition of Naproxen
Published in Organic letters (12-10-2006)“…A macrocyclic receptor based on a bischromenylurea and an α,α‘-(o,o ‘-dialkyl)diphenyl-p-xylylenediamine spacer provides a C 2 chiral cavity to associate…”
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18
A Twitchell Reagent Revival: Biodiesel Generation from Low Cost Oils
Published in Advanced synthesis & catalysis (01-10-2011)“…The transesterification of triglycerides with short‐chain alcohols, such as methanol, is the most used process for the obtention of biodiesel. This is a…”
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A Xanthene-Benzimidazole Receptor with Multiple H-Bond Donors for Carboxylic Acids
Published in European Journal of Organic Chemistry (01-11-2010)“…The combination of two benzimidazole moieties with a spacer formed by a leucine unit and a xanthene skeleton provides an efficient receptor for neutral guests…”
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Thiourea versus the oxyanion hole as a double H-bond donor
Published in Tetrahedron letters (18-08-2008)“…A novel receptor based on the 4,5-diamine-9,9-dimethylxanthene skeleton functionalised with triflamides has been developed and its hydrogen-bonding donor…”
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