Search Results - "Mora, Joana L."
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Single-arm, open-label phase 2 trial of pembrolizumab in patients with leptomeningeal carcinomatosis
Published in Nature medicine (01-08-2020)“…An increasing fraction of patients with metastatic cancer develop leptomeningeal dissemination of disease (LMD), and survival is dismal 1 – 3 . We conducted a…”
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Detection of Leptomeningeal Disease Using Cell-Free DNA From Cerebrospinal Fluid
Published in JAMA network open (02-08-2021)“…Leptomeningeal disease (LMD) is a devastating complication of cancer that is frequently underdiagnosed owing to the low sensitivity of cerebrospinal fluid…”
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Publisher Correction: Single-arm, open-label phase 2 trial of pembrolizumab in patients with leptomeningeal carcinomatosis
Published in Nature medicine (01-08-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Phase II study of ipilimumab and nivolumab in leptomeningeal carcinomatosis
Published in Nature communications (12-10-2021)“…Leptomeningeal disease (LMD) is a common complication from solid tumor malignancies with a poor prognosis and limited treatment options. We present a single…”
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Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases
Published in Nature communications (12-10-2021)“…Leptomeningeal disease (LMD) is a devastating complication of solid tumor malignancies, with dire prognosis and no effective systemic treatment options. Over…”
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Microenvironmental Landscape of Human Melanoma Brain Metastases in Response to Immune Checkpoint Inhibition
Published in Cancer immunology research (03-08-2022)“…Melanoma-derived brain metastases (MBM) represent an unmet clinical need because central nervous system progression is frequently an end stage of the disease…”
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