Search Results - "Mora, David"
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A catalogue of signal molecules that interact with sensor kinases, chemoreceptors and transcriptional regulators
Published in FEMS microbiology reviews (01-01-2022)“…ABSTRACT Bacteria have evolved many different signal transduction systems that sense signals and generate a variety of responses. Generally, most abundant are…”
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The use of isothermal titration calorimetry to unravel chemotactic signalling mechanisms
Published in Environmental microbiology (01-08-2020)“…Summary Chemotaxis is based on the action of chemosensory pathways and is typically initiated by the recognition of chemoeffectors at chemoreceptor…”
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Pseudomonas aeruginosa as a Model To Study Chemosensory Pathway Signaling
Published in Microbiology and molecular biology reviews (17-02-2021)“…Bacteria have evolved a variety of signal transduction mechanisms that generate different outputs in response to external stimuli. Chemosensory pathways are…”
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Anesthetic Management of a Patient With Trisomy 18 Undergoing a Multilevel Spinal Fusion
Published in Journal of medical cases (01-05-2024)“…Trisomy 18 is the second most common autosomal trisomy aside from trisomy 21. Anesthesiologists were unlikely to manage such patients in the past, specifically…”
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Determination of Ligand Profiles for Pseudomonas aeruginosa Solute Binding Proteins
Published in International journal of molecular sciences (17-10-2019)“…Solute binding proteins (SBPs) form a heterogeneous protein family that is found in all kingdoms of life. In bacteria, the ligand-loaded forms bind to…”
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Chemotaxis of the Human Pathogen Pseudomonas aeruginosa to the Neurotransmitter Acetylcholine
Published in mBio (26-04-2022)“…Acetylcholine is a central biological signal molecule present in all kingdoms of life. In humans, acetylcholine is the primary neurotransmitter of the…”
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The Cellular Abundance of Chemoreceptors, Chemosensory Signaling Proteins, Sensor Histidine Kinases, and Solute Binding Proteins of Pseudomonas aeruginosa Provides Insight into Sensory Preferences and Signaling Mechanisms
Published in International journal of molecular sciences (10-01-2023)“…Chemosensory pathways and two-component systems are important bacterial signal transduction systems. In the human pathogen these systems control many virulence…”
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The Molecular Mechanism of Nitrate Chemotaxis via Direct Ligand Binding to the PilJ Domain of McpN
Published in mBio (19-02-2019)“…Chemotaxis and energy taxis permit directed bacterial movements in gradients of environmental cues. Nitrate is a final electron acceptor for anaerobic…”
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Structural Basis for Polyamine Binding at the dCACHE Domain of the McpU Chemoreceptor from Pseudomonas putida
Published in Journal of molecular biology (22-06-2018)“…Many bacteria can move chemotactically to a variety of compounds and the recognition of chemoeffectors by the chemoreceptor ligand binding domain (LBD) defines…”
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High-Affinity Chemotaxis to Histamine Mediated by the TlpQ Chemoreceptor of the Human Pathogen Pseudomonas aeruginosa
Published in mBio (13-11-2018)“…Histamine is a key biological signaling molecule. It acts as a neurotransmitter in the central and peripheral nervous systems and coordinates local…”
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McpQ is a specific citrate chemoreceptor that responds preferentially to citrate/metal ion complexes
Published in Environmental microbiology (01-10-2016)“…Summary Chemoreceptors are at the beginning of chemosensory pathways that mediate chemotaxis. Pseudomonas putida KT2440 is predicted to have 27 chemoreceptors,…”
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South-to-north migration preceded the advent of intensive farming in the Maya region
Published in Nature communications (22-03-2022)“…The genetic prehistory of human populations in Central America is largely unexplored leaving an important gap in our knowledge of the global expansion of…”
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Identification of a Chemoreceptor for C 2 and C 3 Carboxylic Acids
Published in Applied and environmental microbiology (15-08-2015)“…Chemoreceptors are at the beginnings of chemosensory signaling cascades that mediate chemotaxis. Most bacterial chemoreceptors are functionally unannotated and…”
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The pH Robustness of Bacterial Sensing
Published in mBio (26-10-2022)“…Bacteria have evolved many different signal transduction systems to sense and respond to changing environmental conditions. Signal integration is mainly…”
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Identification of a Chemoreceptor for C2 and C3 Carboxylic Acids
Published in Applied and Environmental Microbiology (15-08-2015)“…Chemoreceptors are at the beginnings of chemosensory signaling cascades that mediate chemotaxis. Most bacterial chemoreceptors are functionally unannotated and…”
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The activity of the C4-dicarboxylic acid chemoreceptor of Pseudomonas aeruginosa is controlled by chemoattractants and antagonists
Published in Scientific reports (01-02-2018)“…Chemotaxis toward organic acids has been associated with colonization fitness and virulence and the opportunistic pathogen Pseudomonas aeruginosa exhibits…”
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Mixed displacement–rotation–pressure formulations for linear elasticity
Published in Computer methods in applied mechanics and engineering (01-02-2019)“…We propose a new locking-free family of mixed finite element and finite volume element methods for the approximation of linear elastostatics, formulated in…”
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Functional Annotation of Bacterial Signal Transduction Systems: Progress and Challenges
Published in International journal of molecular sciences (26-11-2018)“…Bacteria possess a large number of signal transduction systems that sense and respond to different environmental cues. Most frequently these are…”
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Evaluation of the genetic diversity in the feijoa accessions maintained at Santa Catarina, Brazil
Published in Crop science (01-01-2020)“…Feijoa [Acca sellowaiana (O. Berg) Burret], also known as pineapple guava or goiabeira‐serrana, is a species of the Myrtaceae family native to southern Brazil…”
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