Search Results - "Mora, Ahmed"

Design, synthesis and bioactivity study on oxygen-heterocyclic-based pyran analogues as effective P-glycoprotein-mediated multidrug resistance in MCF-7/ADR cell by Abd El-Wahab, Ashraf H. F., Borik, Rita M. A., Al-Dies, Al-Anood M., Fouda, Ahmed M., Mohamed, Hany M., El-Eisawy, Raafat A., Mora, Ahmed, El-Nassag, Mohammed A. A., Abd elhady, Ahmed M., Elhenawy, Ahmed A., El-Agrody, Ahmed M.

“…P -glycoprotein ( P -gp) imparts multi-drug resistance (MDR) on the cancers cell and malignant tumor clinical therapeutics. We report a class of newly designed…”
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Discovery of benzochromene derivatives first example with dual cytotoxic activity against the resistant cancer cell MCF-7/ADR and inhibitory effect of the P-glycoprotein expression levels by Al-Harbi, Laila M., Al-Harbi, Eman A., Okasha, Rawda M., El-Eisawy, R. A., El-Nassag, Mohammed A. A., Mohamed, Hany M., Fouda, Ahmed M., Elhenawy, Ahmed A., Mora, Ahmed, El-Agrody, Ahmed M., El-Mawgoud, Heba K. A.

“…A series of 1H-benzo[f]chromene moieties (4a-z) were synthesised under Ultrasonic irradiation and confirmed with spectral analyses. Derivative 4i solely…”
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Synthesis of 9-Hydroxy-1H-Benzo[f]chromene Derivatives with Effective Cytotoxic Activity on MCF7/ADR, P-Glycoprotein Inhibitors, Cell Cycle Arrest and Apoptosis Effects by Albalawi, Fawzia F., El-Nassag, Mohammed A. A., El-Eisawy, Raafat A., Mohamed, Mahmoud Basseem I., Fouda, Ahmed M., Afifi, Tarek H., Elhenawy, Ahmed A., Mora, Ahmed, El-Agrody, Ahmed M., El-Mawgoud, Heba K. A.

“…β-Enaminonitriles bearing 9-hydroxy-1H-benzo[f]chromene moiety was synthesized. The targeted compounds were evaluated for their anti-proliferative activity…”
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Design and Synthesis of Novel Heterocyclic-Based 4H-benzo[h]chromene Moieties: Targeting Antitumor Caspase 3/7 Activities and Cell Cycle Analysis by Alblewi, Fawzia, Okasha, Rawda, Eskandrani, Areej, Afifi, Tarek, Mohamed, Hany, Halawa, Ahmed, Fouda, Ahmed, Al-Dies, Al-Anood, Mora, Ahmed, El-Agrody, Ahmed

“…Novel fused chromenes (4,7–11) and pyrimidines (12–16) were designed, synthesized, and evaluated for their mammary gland breast cancer (MCF-7), human colon…”
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Expression of XCR1 Characterizes the Batf3-Dependent Lineage of Dendritic Cells Capable of Antigen Cross-Presentation by Bachem, Annabell, Hartung, Evelyn, Güttler, Steffen, Mora, Ahmed, Zhou, Xuefei, Hegemann, Anika, Plantinga, Maud, Mazzini, Elisa, Stoitzner, Patrizia, Gurka, Stephanie, Henn, Volker, Mages, Hans W, Kroczek, Richard A

“…Cross-presentation of antigen by dendritic cells (DCs) to CD8(+) T cells is a fundamentally important mechanism in the defense against pathogens and tumors…”
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Ontogenic, Phenotypic, and Functional Characterization of XCR1+ Dendritic Cells Leads to a Consistent Classification of Intestinal Dendritic Cells Based on the Expression of XCR1 and SIRPΠby Becker, Martina, Güttler, Steffen, Bachem, Annabell, Hartung, Evelyn, Mora, Ahmed, Jäkel, Anika, Hutloff, Andreas, Henn, Volker, Mages, Hans Werner, Gurka, Stephanie, Kroczek, Richard A.

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Selective Expression of the Chemokine Receptor XCR1 on Cross-presenting Dendritic Cells Determines Cooperation with CD8 + T Cells by Dorner, Brigitte G., Dorner, Martin B., Zhou, Xuefei, Opitz, Corinna, Mora, Ahmed, Güttler, Steffen, Hutloff, Andreas, Mages, Hans W., Ranke, Katja, Schaefer, Michael, Jack, Robert S., Henn, Volker, Kroczek, Richard A.

“…The expression of the chemokine receptor XCR1 and the function of its ligand XCL1 (otherwise referred to as ATAC, lymphotactin, or SCM-1) remained elusive to…”
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Discovery of pyran annulated heterocyclic scaffolds linked to carboxamide fragments: Anticancer evaluation, topoisomerase I/II, tyrosine kinase receptor inhibition and molecular docking studies by Fouda, Ahmed M., El-Eisawy, R.A., El-Nassag, Mohammed A.A., Mohamed, Hany M., Fekry, Ashraf H.F., El-Mawgoud, Heba K.A., Shati, Ali A., Alfaifi, Mohammad Y., Elbehairi, Serag Eldin I., Elhenawy, Ahmed A., Mora, Ahmed, El-Agrody, Ahmed M.

“…•Tricyclic 4H-benzo[h]chromene and 1H-benzo[f]chromene derivatives were synthesized as potential anticancer agents.•The cytotoxic activity was tested against…”
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In vitro anticancer activity of pyrano[3, 2-c]chromene derivatives with both cell cycle arrest and apoptosis induction by El-Agrody, Ahmed M., Fouda, Ahmed M., Assiri, Mohammed A., Mora, Ahmed, Ali, Tarik E., Alam, Mohammed M., Alfaifi, Mohammad Y.

“…A series of 2-amino-4-aryl-5-oxo-4,5-dihydropyrano[3,2- c ]chromene-3-carbonitrile ( 4a – m ) were synthesized via a one-pot three component condensation…”
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Novel molecular discovery of promising amidine-based thiazole analogues as potent dual Matrix Metalloproteinase-2 and 9 inhibitors: Anticancer activity data with prominent cell cycle arrest and DNA fragmentation analysis effects by Omar, Abdelsattar M., Bajorath, Jürgen, Ihmaid, Saleh, Mohamed, Hany M., El-Agrody, Ahmed M., Mora, Ahmed, El-Araby, Moustafa E., Ahmed, Hany E.A.

“…Novel Molecular Discovery of Promising Amidine-based thiazole analogues as Potent Dual Matrix Metalloproteinase-2 and 9 Inhibitors: Anticancer Activity Data…”
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Microwave synthesis of novel halogenated β-enaminonitriles linked 9-bromo-1H-benzo[f]chromene moieties: Induces cell cycle arrest and apoptosis in human cancer cells via dual inhibition of topoisomerase I and II by Fouda, Ahmed M., Assiri, Mohammed A., Mora, Ahmed, Ali, Tarik E., Afifi, Tarek H., El-Agrody, Ahmed M.

“…Novel halogenated β-enaminonitriles linked 9-bromo-1H-benzo[f]-chromene moieties with dual inhibition of Topoisomerase I and II. [Display omitted]…”
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Frequency of CD4+ regulatory T cells, CD8+ T cells, and human papilloma virus infection in Egyptian Women with breast cancer by Tawfeik, Amany M, Mora, Ahmed, Osman, Ahmed, Moneer, Manar M, El-Sheikh, Nabila, Elrefaei, Mohamed

“…Several subsets of regulatory CD4+ T cells (CD4+ Tregs) have been described in peripheral blood and tumor microenvironment of breast cancer (BC) patients and…”
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Antiproliferative effect, cell cycle arrest and apoptosis generation of novel synthesized anticancer heterocyclic derivatives based 4H-benzo[h]chromene by Alblewi, Fawzia F., Okasha, Rawda M., Hritani, Zainab M., Mohamed, Hany M., El-Nassag, Mohammed A.A., Halawa, Ahmed H., Mora, Ahmed, Fouda, Ahmed M., Assiri, Mohammed A., Al-Dies, Al-Anood M., Afifi, Tarek H., El-Agrody, Ahmed M.

“…[Display omitted] •Design of novel fused chromene and pyrimidine derivatives as promising anticancer agents.•The cytotoxic activity of the new molecules was…”
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A proficient microwave synthesis with structure elucidation and the exploitation of the biological behavior of the newly halogenated 3-amino-1H-benzo[f]chromene molecules, targeting dual inhibition of topoisomerase II and microtubules by Fouda, Ahmed M., Okasha, Rawda M., Alblewi, Fawzia F., Mora, Ahmed, Afifi, Tarek H, El-Agrody, Ahmed M.

“…[Display omitted] •β-enamionitriles, linked 8-bromo-1H-benzo[f]chromene moieties were synthesized as potential anticancer agents.•The cytotoxic activity was…”
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Cell cycle arrest and induction of apoptosis of newly synthesized pyranoquinoline derivatives under microwave irradiation by Fouda, Ahmed M., Youssef, Ayman M. S., Afifi, Tarek H., Mora, Ahmed, El-Agrody, Ahmed M.

“…A set of 2-amino-4-aryl-4 H -pyrano[3,2- h ]quinoline-3-carbonitrile derivatives were prepared via a one-pot, three-component condensation reaction between the…”
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Synthesis of 9-Hydroxy-1 H -Benzo[ f ]chromene Derivatives with Effective Cytotoxic Activity on MCF7/ADR, P -Glycoprotein Inhibitors, Cell Cycle Arrest and Apoptosis Effects by Albalawi, Fawzia F, El-Nassag, Mohammed A A, El-Eisawy, Raafat A, Mohamed, Mahmoud Basseem I, Fouda, Ahmed M, Afifi, Tarek H, Elhenawy, Ahmed A, Mora, Ahmed, El-Agrody, Ahmed M, El-Mawgoud, Heba K A

“…-Enaminonitriles bearing 9-hydroxy-1 -benzo[ ]chromene moiety was synthesized. The targeted compounds were evaluated for their anti-proliferative activity…”
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Ontogenic, Phenotypic, and Functional Characterization of XCR1(+) Dendritic Cells Leads to a Consistent Classification of Intestinal Dendritic Cells Based on the Expression of XCR1 and SIRPα by Becker, Martina, Güttler, Steffen, Bachem, Annabell, Hartung, Evelyn, Mora, Ahmed, Jäkel, Anika, Hutloff, Andreas, Henn, Volker, Mages, Hans Werner, Gurka, Stephanie, Kroczek, Richard A

“…In the past, lack of lineage markers confounded the classification of dendritic cells (DC) in the intestine and impeded a full understanding of their location…”
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MicroRNA-146a-5p and microRNA-210-3p Correlate with T Regulatory Cells Frequency and Predict Asthma Severity in Egyptian Pediatric Population by Eldosoky, Mona A, Hammad, Reham, Rushdi, Areej, Ibrahim, Hanan F, Tawfeik, Amany M, Mora, Ahmed, Fahmy, Sarah F, El-Ashmawy, Hossam, Ali, Elham, Hamed, Dina H, Mohammed, Amena Rezk, Mashaal, Alya, Mohsen, Hanan

“…Severe bronchial asthma (BA) affects 5-10% of children, which imposes socioeconomic burden. Therefore, it is crucial to identify biomarkers for risk…”
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Design and Synthesis of Novel Heterocyclic-Based 4 H -benzo[ h ]chromene Moieties: Targeting Antitumor Caspase 3/7 Activities and Cell Cycle Analysis by Alblewi, Fawzia F, Okasha, Rawda M, Eskandrani, Areej A, Afifi, Tarek H, Mohamed, Hany M, Halawa, Ahmed H, Fouda, Ahmed M, Al-Dies, Al-Anood M, Mora, Ahmed, El-Agrody, Ahmed M

“…Novel fused chromenes ( , ⁻ ) and pyrimidines ( ⁻ ) were designed, synthesized, and evaluated for their mammary gland breast cancer (MCF-7), human colon cancer…”
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