Search Results - "Morán, María A"

Neuronal Induction of the Immunoproteasome in Huntington's Disease by Diaz-Hernandez, Miguel, Hernandez, Felix, Martin-Aparicio, Ester, Gomez-Ramos, Pilar, Moran, Maria A, Castano, Jose G, Ferrer, Isidro, Avila, Jesus, Lucas, Jose J

“…Huntington's disease (HD) inclusions are stained with anti-ubiquitin and anti-proteasome antibodies. This, together with proteasome activity studies on…”
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α-Synuclein accumulates in huntingtin inclusions but forms independent filaments and its deficiency attenuates early phenotype in a mouse model of Huntington's disease by Tomás-Zapico, Cristina, Díez-Zaera, María, Ferrer, Isidre, Gómez-Ramos, Pilar, Morán, María A., Miras-Portugal, M. Teresa, Díaz-Hernández, Miguel, Lucas, José J.

“…Huntington's disease (HD) is the most common of nine inherited neurological disorders caused by expanded polyglutamine (polyQ) sequences which confer…”
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Inhibition of 26S proteasome activity by huntingtin filaments but not inclusion bodies isolated from mouse and human brain by Díaz‐Hernández, Miguel, Valera, Adriana G., Morán, María A., Gómez‐Ramos, Pilar, Alvarez‐Castelao, Beatriz, Castaño, José G., Hernández, Félix, Lucas, José J.

“…In Huntington's disease (HD), as in the rest of CAG triplet‐repeat disorders, the expanded polyglutamine (polyQ)‐containing proteins form intraneuronal…”
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Full Motor Recovery Despite Striatal Neuron Loss and Formation of Irreversible Amyloid-Like Inclusions in a Conditional Mouse Model of Huntington's Disease by Diaz-Hernandez, Miguel, Torres-Peraza, Jesus, Salvatori-Abarca, Alejandro, Moran, Maria A, Gomez-Ramos, Pilar, Alberch, Jordi, Lucas, Jose J

“…The primary mechanism responsible for Huntington's disease remains unknown. Postulated early pathogenic events include the following: impaired protein folding,…”
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Biochemical, Ultrastructural, and Reversibility Studies on Huntingtin Filaments Isolated from Mouse and Human Brain by Diaz-Hernandez, Miguel, Moreno-Herrero, Fernando, Gomez-Ramos, Pilar, Moran, Maria A, Ferrer, Isidro, Baro, Arturo M, Avila, Jesus, Hernandez, Felix, Lucas, Jose J

“…Huntington's disease (HD) and eight additional inherited neurological disorders are caused by CAG triplet-repeat expansions leading to expanded…”
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Decreased nuclear β-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3β conditional transgenic mice by Lucas, José J., Hernández, Félix, Gómez-Ramos, Pilar, Morán, María A., Hen, René, Avila, Jesús

“…Glycogen synthase kinase‐3β (GSK‐3β) has been postulated to mediate Alzheimer's disease tau hyperphosphorylation, β‐amyloid‐induced neurotoxicity and…”
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GSK3β overexpression induces neuronal death and a depletion of the neurogenic niches in the dentate gyrus by Sirerol-Piquer, MaSalomé, Gomez-Ramos, Pilar, Hernández, Félix, Perez, Mar, Morán, María A., Fuster-Matanzo, Almudena, Lucas, José J., Avila, Jesús, García-Verdugo, Jose Manuel

“…Overexpression of GSK3β in transgenic mice induces learning deficits and some features associated with Alzheimer's disease (AD), including dentate gyrus (DG)…”
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Cooexpression of FTDP-17 tau and GSK-3β in transgenic mice induce tau polymerization and neurodegeneration by Engel, Tobias, Lucas, José J., Gómez-Ramos, Pilar, Moran, María A., Ávila, Jesús, Hernández, Félix

“…Here we have tested whether tau modification either by point mutation or by hyperphosphorylation can exert maximal pathogenic effects or if, on the contrary,…”
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Decreased nuclear [beta]-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3[beta] conditional transgenic mice by Lucas, José J, Hernández, Félix, Gómez-Ramos, Pilar, Morán, María A, Hen, René, Avila, Jesús

“…Glycogen synthase kinase-3β (GSK-3β) has been postulated to mediate Alzheimer's disease tau hyperphosphorylation, β-amyloid-induced neurotoxicity and…”
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Are vancomycin dosing guidelines followed? A mixed methods study of vancomycin prescribing practices by Carland, Jane E., Stocker, Sophie L., Baysari, Melissa T., Li, Crystal, Själin, Jacqueline, Moran, Maria A., Tang, Sarah, Sandaradura, Indy, Elhage, Tania, Gilbey, Timothy, Williams, Kenneth M., Marriott, Deborah J. E., Day, Richard O.

“…Aims Despite the availability of international consensus guidelines, vancomycin dosing and therapeutic drug monitoring (TDM) remain suboptimal. This study…”
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Microtubule-associated protein MAP1B showing a fetal phosphorylation pattern is present in sites of neurofibrillary degeneration in brains of Alzheimer's disease patients by Ulloa, L, Montejo de Garcini, E, Gómez-Ramos, P, Morán, M A, Avila, J

“…Alzheimer's disease results in the appearance of cytoskeletal disorders yielding pathological structures such a neurofibrillary tangles or dystrophic neurites…”
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Biochemical, ultrastructural, and reversiblity studies on Huntingtin filaments isolated from mouse and human brain by Díaz-Hernández, Miguel, Moreno-Herrero, Fernando, Gómez-Ramos, Pilar, Morán, María A, Ferrer, Isidro (Ferrer Abizanda), Baró, Arturo M, Avila, Jesús, Hernández, Félix, Lucas, José J

“…Huntington's disease (HD) and eight additional inherited neurological disorders are caused by CAG triplet-repeat expansions leading to expanded…”
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Cooexpression of FTDP-17 tau and GSK-3beta in transgenic mice induce tau polymerization and neurodegeneration by Engel, Tobias, Lucas, José J, Gómez-Ramos, Pilar, Moran, María A, Avila, Jesús, Hernández, Félix

“…Here we have tested whether tau modification either by point mutation or by hyperphosphorylation can exert maximal pathogenic effects or if, on the contrary,…”
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Decreased nuclear b-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3b conditional transgenic mice by Lucas, Jose J, Hernandez, Felix, Gomez-Ramos, Pilar, Moran, Maria A, Hen, Rene, Avila, Jesus

“…Glycogen synthase kinase-3b (GSK-3b) has been postulated to mediate Alzheimer's disease tau hyperphosphorylation, b-amyloid-induced neurotoxicity and…”
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