Search Results - "Moquet, Jayne"
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DNA damage foci: Meaning and significance
Published in Environmental and molecular mutagenesis (01-07-2015)“…The discovery of DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the…”
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2
The second gamma-H2AX assay inter-comparison exercise carried out in the framework of the European biodosimetry network (RENEB)
Published in International journal of radiation biology (02-01-2017)“…Purpose: Within the EU RENEB project, seven laboratories have taken part in training and harmonisation activities to strengthen triage gamma-H2AX-based…”
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3
Direct Involvement of Retinoblastoma Family Proteins in DNA Repair by Non-homologous End-Joining
Published in Cell reports (Cambridge) (31-03-2015)“…Deficiencies in DNA double-strand break (DSB) repair lead to genetic instability, a recognized cause of cancer initiation and evolution. We report that the…”
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4
An ionising radiation-induced specific transcriptional signature of inflammation-associated genes in whole blood from radiotherapy patients: a pilot study
Published in Radiation oncology (London, England) (03-05-2021)“…This communication reports the identification of a new panel of transcriptional changes in inflammation-associated genes observed in response to ionising…”
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Gamma-H2AX biodosimetry for use in large scale radiation incidents: comparison of a rapid '96 well lyse/fix' protocol with a routine method
Published in PeerJ (San Francisco, CA) (06-03-2014)“…Following a radiation incident, preliminary dose estimates made by γ-H2AX foci analysis can supplement the early triage of casualties based on clinical…”
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6
In vitro study of radiosensitivity in colorectal cancer cell lines associated with Lynch syndrome
Published in Frontiers in public health (04-04-2024)“…Lynch syndrome patients have an inherited predisposition to cancer due to a deficiency in DNA mismatch repair (MMR) genes which could lead to a higher risk of…”
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RENEB biodosimetry intercomparison analyzing translocations by FISH
Published in International journal of radiation biology (02-01-2017)“…Purpose: In the framework of RENEB, several biodosimetry exercises were conducted analyzing different endpoints. Among them, the analysis of translocations is…”
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A New Cytogenetic Biodosimetry Image Repository for the Dicentric Assay
Published in Radiation protection dosimetry (01-12-2016)“…The BioDoseNet was founded by the World Health Organization as a global network of biodosimetry laboratories for building biodosimetry laboratory capacities in…”
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Capabilities of the RENEB network for research and large scale radiological and nuclear emergency situations
Published in International journal of radiation biology (02-01-2017)“…Purpose: To identify and assess, among the participants in the RENEB (Realizing the European Network of Biodosimetry) project, the emergency preparedness,…”
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10
Verification by the FISH translocation assay of historic doses to Mayak workers from external gamma radiation
Published in Radiation and environmental biophysics (01-11-2015)“…The aim of this study was to apply the fluorescence in situ hybridization (FISH) translocation assay in combination with chromosome painting of peripheral…”
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A Simplified Calyculin A-Induced Premature Chromosome Condensation (PCC) Protocol for the Biodosimetric Analysis of High-Dose Exposure to Gamma Radiation
Published in Radiation research (01-06-2020)“…Chemical-induced premature chromosome condensation (PCC) is an alternative biodosimetry method to the gold-standard dicentric analysis for ionizing radiation…”
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Scoring rings in the cell fusion-induced premature chromosome condensation (PCC) assay for high dose radiation exposure estimation after gamma-ray exposure
Published in International journal of radiation biology (02-09-2019)“…Purpose: This study aimed to construct a calibration curve for high-dose exposure using cell fusion-induced premature chromosome condensation (PCC). Some of…”
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The future of biological dosimetry in mass casualty radiation emergency response, personalized radiation risk estimation and space radiation protection
Published in International journal of radiation biology (04-03-2022)“…Well established and newer biodosimetric techniques show promise for a number of future dosimetry or wider research application. PCC: Premature chromosome…”
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Applicability of Scoring Calyculin A-Induced Premature Chromosome Condensation Objects for Dose Assessment Including for Radiotherapy Patients
Published in Cytogenetic and genome research (01-03-2024)“…As an extension to a previous study, a linear calibration curve covering doses from 0 to 10 Gy was constructed and evaluated in the present study using…”
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Higher Incidence of Chromosomal Aberrations in Operators Performing a Large Volume of Endovascular Procedures
Published in Circulation (New York, N.Y.) (14-06-2022)Get full text
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16
Inverse dose-rate effect of ionising radiation on residual 53BP1 foci in the eye lens
Published in Scientific reports (18-07-2019)“…The influence of dose rate on radiation cataractogenesis has yet to be extensively studied. One recent epidemiological investigation suggested that protracted…”
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RENEB Inter-Laboratory Comparison 2021: The Gamma-H2AX Foci Assay
Published in Radiation research (01-06-2023)“…The Running the European Network of biological and retrospective dosimetry (RENEB) network of laboratories has a range of biological and physical dosimetry…”
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Radiation Biomarkers in Large Scale Human Health Effects Studies
Published in Journal of personalized medicine (03-10-2020)“…Following recent developments, the RENEB network (Running the European Network of biological dosimetry and physical retrospective dosimetry) is in an excellent…”
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Potential risks associated with the use of ionizing radiation for imaging and treatment of colorectal cancer in Lynch syndrome patients
Published in Familial cancer (01-01-2023)“…The aim of this review is to investigate the literature pertaining to the potential risks of low-dose ionizing radiation to Lynch syndrome patients by use of…”
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RENEB intercomparisons applying the conventional Dicentric Chromosome Assay (DCA)
Published in International journal of radiation biology (02-01-2017)“…Purpose: Two quality controlled inter-laboratory exercises were organized within the EU project 'Realizing the European Network of Biodosimetry (RENEB)' to…”
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