Search Results - "Moosa, Yunus"

Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma by Cele, Sandile, Gazy, Inbal, Jackson, Laurelle, Hwa, Shi-Hsia, Tegally, Houriiyah, Lustig, Gila, Giandhari, Jennifer, Pillay, Sureshnee, Wilkinson, Eduan, Naidoo, Yeshnee, Karim, Farina, Ganga, Yashica, Khan, Khadija, Bernstein, Mallory, Balazs, Alejandro B., Gosnell, Bernadett I., Hanekom, Willem, Moosa, Mahomed-Yunus S., Lessells, Richard J., de Oliveira, Tulio, Sigal, Alex

“…SARS-CoV-2 variants of concern (VOC) have arisen independently at multiple locations 1 , 2 and may reduce the efficacy of current vaccines that target the…”
Get full text

Prognostic variables and 4-year survival outcomes in CD20 Positive AIDS-Related Lymphoma in the Anti-retroviral treatment era: A Retrospective Review from a Single Centre in KwaZulu-Natal, South Africa by Rapiti, Nadine, Abdelatif, Nada, Moosa, Mahomed-Yunus S

“…Objective To describe 4-year survival outcomes and assess the value of established and additional relevant variables to predict complete response (CR),…”
Get full text

Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection by Khan, Khadija, Karim, Farina, Ganga, Yashica, Bernstein, Mallory, Jule, Zesuliwe, Reedoy, Kajal, Cele, Sandile, Lustig, Gila, Amoako, Daniel, Wolter, Nicole, Samsunder, Natasha, Sivro, Aida, San, James Emmanuel, Giandhari, Jennifer, Tegally, Houriiyah, Pillay, Sureshnee, Naidoo, Yeshnee, Mazibuko, Matilda, Miya, Yoliswa, Ngcobo, Nokuthula, Manickchund, Nithendra, Magula, Nombulelo, Karim, Quarraisha Abdool, von Gottberg, Anne, Abdool Karim, Salim S., Hanekom, Willem, Gosnell, Bernadett I., Lessells, Richard J., de Oliveira, Tulio, Moosa, Mahomed-Yunus S., Sigal, Alex

“…SARS-CoV-2 Omicron (B.1.1.529) BA.4 and BA.5 sub-lineages, first detected in South Africa, have changes relative to Omicron BA.1 including substitutions in the…”
Get full text

SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape by Cele, Sandile, Karim, Farina, Lustig, Gila, San, James Emmanuel, Hermanus, Tandile, Tegally, Houriiyah, Snyman, Jumari, Moyo-Gwete, Thandeka, Wilkinson, Eduan, Bernstein, Mallory, Khan, Khadija, Hwa, Shi-Hsia, Tilles, Sasha W., Singh, Lavanya, Giandhari, Jennifer, Mthabela, Ntombifuthi, Mazibuko, Matilda, Ganga, Yashica, Gosnell, Bernadett I., Karim, Salim S. Abdool, Hanekom, Willem, Van Voorhis, Wesley C., Ndung’u, Thumbi, Lessells, Richard J., Moore, Penny L., Moosa, Mahomed-Yunus S., de Oliveira, Tulio, Sigal, Alex

“…Characterizing SARS-CoV-2 evolution in specific geographies may help predict properties of the variants that come from these regions. We mapped neutralization…”
Get full text

T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy by Lustig, Gila, Cele, Sandile, Karim, Farina, Derache, Anne, Ngoepe, Abigail, Khan, Khadija, Gosnell, Bernadett I, Moosa, Mahomed-Yunus S, Ntshuba, Ntombi, Marais, Suzaan, Jeena, Prakash M, Govender, Katya, Adamson, John, Kløverpris, Henrik, Gupta, Ravindra K, Harrichandparsad, Rohen, Patel, Vinod B, Sigal, Alex

“…HIV cerebrospinal fluid (CSF) escape, where HIV is suppressed in blood but detectable in CSF, occurs when HIV persists in the CNS despite antiretroviral…”
Get full text

A systematic review of hepatic tuberculosis with considerations in human immunodeficiency virus co-infection by Hickey, Andrew J, Gounder, Lilishia, Moosa, Mahomed-Yunus S, Drain, Paul K

“…Mycobacterium tuberculosis (TB) infection of the liver, known as hepatic TB, is an extrapulmonary manifestation of TB. Hepatic TB has become more prevalent,…”
Get full text

Evolution and neutralization escape of the SARS-CoV-2 BA.2.86 subvariant by Khan, Khadija, Lustig, Gila, Römer, Cornelius, Reedoy, Kajal, Jule, Zesuliwe, Karim, Farina, Ganga, Yashica, Bernstein, Mallory, Baig, Zainab, Jackson, Laurelle, Mahlangu, Boitshoko, Mnguni, Anele, Nzimande, Ayanda, Stock, Nadine, Kekana, Dikeledi, Ntozini, Buhle, van Deventer, Cindy, Marshall, Terry, Manickchund, Nithendra, Gosnell, Bernadett I., Lessells, Richard J., Karim, Quarraisha Abdool, Abdool Karim, Salim S., Moosa, Mahomed-Yunus S., de Oliveira, Tulio, von Gottberg, Anne, Wolter, Nicole, Neher, Richard A., Sigal, Alex

“…Omicron BA.2.86 subvariant differs from Omicron BA.2 as well as recently circulating variants by over 30 mutations in the spike protein alone. Here we report…”
Get full text

Symbolic and anticipated HIV stigma are associated with mental health and education in South Africa by Meyer, Megan F., Moe, Caitlin A., Galagan, Sean R., Govere, Sabina, Gosnell, Bernadett I., Moosa, Mahomed-Yunus, Drain, Paul K.

“…HIV stigma continues to act as a barrier to HIV care in South Africa, necessitating further research on the intersections of socioeconomic factors and the…”
Get full text

Unsuppressed HIV infection impairs T cell responses to SARS-CoV-2 infection and abrogates T cell cross-recognition by Nkosi, Thandeka, Chasara, Caroline, Papadopoulos, Andrea O, Nguni, Tiza L, Karim, Farina, Moosa, Mahomed-Yunus S, Gazy, Inbal, Jambo, Kondwani, Hanekom, Willem, Sigal, Alex, Ndhlovu, Zaza M

“…In some instances, unsuppressed HIV has been associated with severe COVID-19 disease, but the mechanisms underpinning this susceptibility are still unclear…”
Get full text

Early transmission of SARS-CoV-2 in South Africa: An epidemiological and phylogenetic report by Giandhari, Jennifer, Pillay, Sureshnee, Wilkinson, Eduan, Tegally, Houriiyah, Sinayskiy, Ilya, Schuld, Maria, Lourenço, José, Chimukangara, Benjamin, Lessells, Richard, Moosa, Yunus, Gazy, Inbal, Fish, Maryam, Singh, Lavanya, Sedwell Khanyile, Khulekani, Fonseca, Vagner, Giovanetti, Marta, Carlos Junior Alcantara, Luiz, Petruccione, Francesco, de Oliveira, Tulio

“…•The early COVID-19 epidemic in South Africa was highly heterogeneous looking at the epidemiological progression between major provinces.•Early transmission in…”
Get full text

Clinical and mycological predictors of cryptococcosis-associated immune reconstitution inflammatory syndrome by CHANG, Christina C, DORASAMY, Afton A, LEWIN, Sharon R, FRENCH, Martyn A, GOSNELL, Bernadett I, ELLIOTT, Julian H, SPELMAN, Tim, OMARJEE, Saleha, NARANBHAI, Vivek, COOVADIA, Yacoob, NDUNG'U, Thumbi, MOOSA, Mohamed-Yunus S

“…HIV-infected patients with treated cryptococcal meningitis are at risk for further neurological deterioration after commencing combination antiretroviral…”
Get full text

Determinants of health-related quality of life in people with Human Immunodeficiency Virus, failing first-line treatment in Africa by Rautenberg, Tamlyn A, Ng, Shu Kay, George, Gavin, Moosa , Mahomed-Yunus S, McCluskey, Suzanne M, Gilbert, Rebecca F, Pillay, Selvan, Aturinda, Isaac, Ard, Kevin L, Muyindike , Winnie R, Musinguzi, Nicholas, Masette, Godfrey, Pillay, Melendhran, Moodley, Pravi, Brijkumar, Jaysingh, Gandhi, Rajesh T, Johnson, Brent, Sunpath, Henry, Bwana, Mwebesa B, Marconi, Vincent C, Siedner, Mark J

“…Abstract Background Antiretroviral treatment improves health related quality of life (HRQoL) of people with human immunodeficiency virus (PWH). However, one…”
Get full text

Resistance Testing for Management of HIV Virologic Failure in Sub-Saharan Africa : An Unblinded Randomized Controlled Trial by Siedner, Mark J, Moosa, Mahomed-Yunus S, McCluskey, Suzanne, Gilbert, Rebecca F, Pillay, Selvan, Aturinda, Isaac, Ard, Kevin, Muyindike, Winnie, Musinguzi, Nicholas, Masette, Godfrey, Pillay, Melendhran, Moodley, Pravikrishnen, Brijkumar, Jaysingh, Rautenberg, Tamlyn, George, Gavin, Gandhi, Rajesh T, Johnson, Brent A, Sunpath, Henry, Bwana, Mwebesa B, Marconi, Vincent C

“…Virologic failure in HIV predicts the development of drug resistance and mortality. Genotypic resistance testing (GRT), which is the standard of care after…”
Get full text

Celebrating 21 years and introducing the 21st anniversary issue by Moosa, Yunus, Jankelowitz, Lauren

“…Abstract only…”
Get full text

Validation of clinic-based cryptococcal antigen lateral flow assay screening in HIV-infected adults in South Africa by Drain, Paul K., Hong, Ting, Krows, Meighan, Govere, Sabina, Thulare, Hilary, Wallis, Carole L., Gosnell, Bernadett I., Moosa, Mahomed-Yunus, Bassett, Ingrid V., Celum, Connie

“…Since rapid cryptococcal antigen lateral flow assays (CrAg LFA) may expedite treatment of HIV-associated cryptococcal infections, we sought to validate…”
Get full text

Adult antiretroviral therapy guidelines 2017 by van Vuuren, Cloete, Conradie, Francesca, Pakade, Yoliswa, Davies, Natasha, Meintjes, Graeme, Nash, Jennifer, Moosa, Yunus, Manzini, Thandekile, Woods, Joana, Moorhouse, Michelle A., Nel, Jeremy, Venter, Francois, Mathe, Moeketsi, Dlamini, Sipho, Van Zyl, Gert, Carmona, Sergio

“…These guidelines are intended as an update to those published in the Southern African Journal of HIV Medicine in 2014 and the update on when to initiate…”
Get full text

Clinic-based diabetes screening at the time of HIV testing and associations with poor clinical outcomes in South Africa: a cohort study by Kubiak, Rachel W, Kratz, Mario, Motala, Ayesha A, Galagan, Sean, Govere, Sabina, Brown, Elisabeth R, Moosa, Mahomed-Yunus S, Drain, Paul K

“…HIV clinical care programs in high burden settings are uniquely positioned to facilitate diabetes diagnosis, which is a major challenge. However, in…”
Get full text

Hepatitis B prevalence and risk factors among adults living with HIV in South Africa: a clinic-based cohort study by Shivakumar, Megana, Moe, Caitlin A, Bardon, Ashley, Krows, Meighan, Govere, Sabina, Moosa, Mahomed Yunus S, Celum, Connie, Drain, Paul K

“…People living with HIV (PLHIV) may have concurrent Hepatitis B Virus (HBV) infection, and certain antiretroviral therapies are recommended for HBV-HIV…”
Get full text

Clearance of persistent SARS-CoV-2 associates with increased neutralizing antibodies in advanced HIV disease post-ART initiation by Karim, Farina, Riou, Catherine, Bernstein, Mallory, Jule, Zesuliwe, Lustig, Gila, van Graan, Strauss, Keeton, Roanne S., Upton, Janine-Lee, Ganga, Yashica, Khan, Khadija, Reedoy, Kajal, Mazibuko, Matilda, Govender, Katya, Thambu, Kershnee, Ngcobo, Nokuthula, Venter, Elizabeth, Makhado, Zanele, Hanekom, Willem, von Gottberg, Anne, Hoque, Monjurul, Karim, Quarraisha Abdool, Abdool Karim, Salim S., Manickchund, Nithendra, Magula, Nombulelo, Gosnell, Bernadett I., Lessells, Richard J., Moore, Penny L., Burgers, Wendy A., de Oliveira, Tulio, Moosa, Mahomed-Yunus S., Sigal, Alex

“…SARS-CoV-2 clearance requires adaptive immunity but the contribution of neutralizing antibodies and T cells in different immune states is unclear. Here we ask…”
Get full text

Laboratory Reflex and Clinic-Based Point-of-Care Cryptococcal Antigen Screening for Preventing Meningitis and Mortality Among People Living With HIV by Drain, Paul K., Galagan, Sean R., Govere, Sabina, Krows, Meighan, Thulare, Hilary, Wallis, Carole L., Gosnell, Bernadett I., Moosa, Mahomed-Yunus, Celum, Connie, Bassett, Ingrid V.

“…Cryptococcosis remains a leading cause of meningitis and mortality among people living with HIV (PLHIV) worldwide. We sought to evaluate laboratory-based…”
Get full text