Search Results - "Moosa, S."
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The views of public service managers on the implementation of National Health Insurance in primary care: a case of Johannesburg Health District, Gauteng Province, Republic of South Africa
Published in BMC health services research (15-09-2021)“…The South African government is implementing National Health Insurance (NHI) as a monopsony health care financing mechanism to drive the country towards…”
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Two South African patients with PGAP3-related Mabry syndrome with unusually low alkaline phosphatase levels
Published in SAJCH : the South African journal of child health (01-12-2022)“…Hyperphosphatasia with mental retardation syndrome (HPMRS), also known as Mabry syndrome, is an autosomal recessive disease that is associated with inherited…”
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Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma
Published in Nature (London) (06-05-2021)“…SARS-CoV-2 variants of concern (VOC) have arisen independently at multiple locations 1 , 2 and may reduce the efficacy of current vaccines that target the…”
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Adaptive state-dependent impulsive observer design for nonlinear deterministic and stochastic dynamics with time-delays
Published in ISA transactions (01-03-2020)“…The present research has introduced a novel adaptive state-dependent impulsive observer (ASDIO) used to control diverse nonlinear systems with time-varying…”
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Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection
Published in Nature communications (10-08-2022)“…SARS-CoV-2 Omicron (B.1.1.529) BA.4 and BA.5 sub-lineages, first detected in South Africa, have changes relative to Omicron BA.1 including substitutions in the…”
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SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape
Published in Cell host & microbe (09-02-2022)“…Characterizing SARS-CoV-2 evolution in specific geographies may help predict properties of the variants that come from these regions. We mapped neutralization…”
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The prevalence of burnout among registrars in the School of Clinical Medicine at the University of the Witwatersrand, Johannesburg, South Africa
Published in South African medical journal (01-09-2019)“…Background. Burnout is a response to prolonged stress and consists of three elements: emotional exhaustion (EE), depersonalisation (DP), and feelings of…”
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Prediction of the Ultimate Strength of Notched and Unnotched IM7/977-3 Laminated Composites Using a Micromechanics Approach
Published in Polymers (11-10-2021)“…This paper proposes a multi-scale analysis technique based on the micromechanics of failure (MMF) to predict and investigate the damage progression and…”
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Prognostic variables and 4-year survival outcomes in CD20 Positive AIDS-Related Lymphoma in the Anti-retroviral treatment era: A Retrospective Review from a Single Centre in KwaZulu-Natal, South Africa
Published in PloS one (01-09-2022)“…Objective To describe 4-year survival outcomes and assess the value of established and additional relevant variables to predict complete response (CR),…”
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Lemierre’s syndrome: A rare complication of acute bacterial pharyngitis
Published in Southern African journal of infectious diseases (09-04-2024)“…Lemierre’s syndrome is a rare clinical syndrome of septic thrombophlebitis following a bacterial oropharyngeal infection. Lemierre’s syndrome can be difficult…”
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Evolution and neutralization escape of the SARS-CoV-2 BA.2.86 subvariant
Published in Nature communications (06-12-2023)“…Omicron BA.2.86 subvariant differs from Omicron BA.2 as well as recently circulating variants by over 30 mutations in the spike protein alone. Here we report…”
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T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy
Published in PLoS pathogens (23-09-2021)“…HIV cerebrospinal fluid (CSF) escape, where HIV is suppressed in blood but detectable in CSF, occurs when HIV persists in the CNS despite antiretroviral…”
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Unsuppressed HIV infection impairs T cell responses to SARS-CoV-2 infection and abrogates T cell cross-recognition
Published in eLife (26-07-2022)“…In some instances, unsuppressed HIV has been associated with severe COVID-19 disease, but the mechanisms underpinning this susceptibility are still unclear…”
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Clinical and mycological predictors of cryptococcosis-associated immune reconstitution inflammatory syndrome
Published in AIDS (London) (24-08-2013)“…HIV-infected patients with treated cryptococcal meningitis are at risk for further neurological deterioration after commencing combination antiretroviral…”
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Clinical and cardiovascular magnetic resonance profile of cardiomyopathy patients from South Africa: Pilot of the IMHOTEP study
Published in International journal of cardiology (15-03-2024)“…Cardiomyopathy is an important cause of heart failure, however, there is notable lack of data on causes and manifestations of cardiomyopathy in Africa. The…”
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Determinants of health-related quality of life in people with Human Immunodeficiency Virus, failing first-line treatment in Africa
Published in Health and quality of life outcomes (21-08-2023)“…Abstract Background Antiretroviral treatment improves health related quality of life (HRQoL) of people with human immunodeficiency virus (PWH). However, one…”
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A young adult with leptospirosis associated acute inflammatory demyelinating polyneuropathy
Published in Southern African journal of infectious diseases (21-12-2023)“…Abstract only…”
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Hepatitis B prevalence and risk factors among adults living with HIV in South Africa: a clinic-based cohort study
Published in BMC infectious diseases (31-08-2024)“…People living with HIV (PLHIV) may have concurrent Hepatitis B Virus (HBV) infection, and certain antiretroviral therapies are recommended for HBV-HIV…”
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Clearance of persistent SARS-CoV-2 associates with increased neutralizing antibodies in advanced HIV disease post-ART initiation
Published in Nature communications (15-03-2024)“…SARS-CoV-2 clearance requires adaptive immunity but the contribution of neutralizing antibodies and T cells in different immune states is unclear. Here we ask…”
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Clinic-based diabetes screening at the time of HIV testing and associations with poor clinical outcomes in South Africa: a cohort study
Published in BMC infectious diseases (10-08-2021)“…HIV clinical care programs in high burden settings are uniquely positioned to facilitate diabetes diagnosis, which is a major challenge. However, in…”
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