Search Results - "Moorthy, Narayana Subbiah Hari Narayana"
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Lysinated Multiwalled Carbon Nanotubes with Carbohydrate Ligands as an Effective Nanocarrier for Targeted Doxorubicin Delivery to Breast Cancer Cells
Published in Molecules (Basel, Switzerland) (01-11-2022)“…Multiwalled carbon nanotubes (MWCNTs) are elongated, hollow cylindrical nanotubes made of sp2 carbon. MWCNTs have attracted significant attention in the area…”
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Microwave-Assisted Functionalization of Multi-Walled Carbon Nanotubes for Biosensor and Drug Delivery Applications
Published in Pharmaceutics (19-01-2023)“…Microwave-assisted synthetic methods have emerged as a popular technique for surface modification and the functionalization of multi-walled carbon nanotubes…”
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Comparative Studies on Conventional and Microwave Assisted Synthesis of Benzimidazole and Their 2-Substituted Derivative with the Effect of Salt Form of Reactant
Published in Chemical & pharmaceutical bulletin (2007)“…Benzimidazole and their derivative were reported to have wide biological activities and were synthesized by using different solvents and ring closing agents…”
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Synthesis, Biological Evaluation and In Silico Metabolic and Toxicity Prediction of Some Flavanone Derivatives
Published in Chemical & Pharmaceutical Bulletin (2006)“…Flavones chemically are anthoxanthins, occur either in the free state or as glycosides associated with tannins (flavanoids). Flavanoids (derivatives of…”
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Molecular Dynamic Simulations-Based Conformational Analysis and Binding Study of CP-225917 on Farnesyl Transferase Enzyme
Published in Medical sciences forum (01-11-2022)“…CP-225917 was isolated from unidentified fungi and exhibits farnesyl transferase and squalene synthase inhibitory activity. In the present investigation,…”
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In silico based structural analysis of some piperidine analogs as farnesyltransferase inhibitors
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01-09-2012)“…In silico based QSAR and pharmacophore analyses of a series of piperidine derivatives were performed in order to investigate the structural features of the…”
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Quantitative Structure–Activity Relationships of Selective Antagonists of Glucagon Receptor Using QuaSAR Descriptors
Published in Chemical & Pharmaceutical Bulletin (2006)“…In the present paper, quantitative structure activity relationship (QSAR) approach was applied to understand the affinity and selectivity of a novel series of…”
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Targeted Delivery of Doxorubicin to Breast Cancer Cells by Multiwalled Carbon Nanotubes Functionalized with Lysine via 1,3-Dipolar Cycloaddition and Conjugation with Sugar Moieties
Published in Medical sciences forum (01-11-2022)“…Multiwalled carbon nanotubes (MWCNTs) have attracted considerable multidisciplinary interest and biomedical applications, such as drug delivery, because of…”
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Design, Synthesis and Biological Evaluation of Novel 1H-benzo[d]imidazole Derivatives as Fatty Acid Synthase (FASN) Inhibitors for Cancer Treatment
Published in Medical sciences forum (01-11-2022)“…FASN is a metabolic oncoprotein that is overexpressed in multiple cancers and regulates the fatty acid requirements of proliferating cells. Thus, FASN has been…”
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Classification analysis of fatty acid synthase inhibitors using multialgorithms on topological descriptors and structural fingerprints
Published in Chemical biology & drug design (01-02-2023)“…Fatty acid synthase (FASN) is one of the enzymes required for fatty acid biosynthesis and is expressed as low or absent in most normal cells/tissues. However,…”
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