Search Results - "Moore IV, Joseph B"
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Matricellular protein CCN1 promotes collagen alignment and scar integrity after myocardial infarction
Published in Matrix biology (01-11-2024)“…•Fibroblast-specific ablation of CCN1 neither impacts cardiac function nor myocardial collagen levels; however, it disrupts collagen fibril organization and…”
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Effect of Molecular Weight on Sonoporation-Mediated Uptake in Human Cells
Published in Ultrasound in medicine & biology (01-12-2018)“…Ultrasound-induced microbubble destruction can enhance drug delivery to cells. The molecular weight of therapeutic compounds varies significantly (from <1 kDa…”
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The Effect of Cardiogenic Factors on Cardiac Mesenchymal Cell Anti-Fibrogenic Paracrine Signaling and Therapeutic Performance
Published in Theranostics (2020)“…Intrinsic cardiogenic factor expression, a proxy for cardiomyogenic lineage commitment, may be an important determinant of donor cell cardiac reparative…”
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C-Kit Promotes Growth and Migration of Human Cardiac Progenitor Cells via the PI3K-AKT and MEK-ERK Pathways
Published in PloS one (16-10-2015)“…A recent phase I clinical trial (SCIPIO) has shown that autologous c-kit+ cardiac progenitor cells (CPCs) improve cardiac function and quality of life when…”
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Distinct ribosome maturation defects in yeast models of Diamond-Blackfan anemia and Shwachman-Diamond syndrome
Published in Haematologica (Roma) (01-01-2010)“…Diamond-Blackfan anemia and Shwachman-Diamond syndrome are inherited bone marrow failure syndromes linked to defects in ribosome synthesis. The purpose of this…”
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Clinical value of non-coding RNAs in cardiovascular, pulmonary, and muscle diseases
Published in American Journal of Physiology: Cell Physiology (01-01-2020)“…Although a majority of the mammalian genome is transcribed to RNA, mounting evidence indicates that only a minor proportion of these transcriptional products…”
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Investigation of RNA Editing Sites within Bound Regions of RNA-Binding Proteins
Published in Biotech (Basel) (29-11-2019)“…Studies in epitranscriptomics indicate that RNA is modified by a variety of enzymes. Among these RNA modifications, adenosine to inosine (A-to-I) RNA editing…”
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Transient Ex Vivo Inhibition of Heme Oxygenase 1 (HO-1) in Hematopoietic Stem/Progenitor Cells (HSPCs) By Small-Molecule Inhibitors Enhances Their Migratory Responsiveness to Bone Marrow (BM)-Secreted Chemoattractants a Novel and Simple Strategy to Improve Homing of HSPCs
Published in Blood (03-12-2015)“…Background. Heme oxygenase 1 (HO-1) is an inducible stress-response enzyme that not only catalyzes the degradation of heme (e.g., released from erythrocytes)…”
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A novel macrophage subtype directs hematopoietic stem cell homing and retention
Published in Annals of translational medicine (01-07-2019)Get full text
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Circular RNAs as diagnostic tool for renal transplant patients with acute rejection
Published in Annals of translational medicine (01-12-2019)Get full text
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