Search Results - "Moore II, DH"
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P5-05-04: Bipshenol-A Modulates Estrogen Receptor Alpha and Compromises Tamoxifen-Induced Apoptosis
Published in Cancer research (Chicago, Ill.) (15-12-2011)“…Abstract BACKGROUND: Antiestrogens are important for treatment and prevention of breast cancer. Such drugs influence multiple pathways involved in regulation…”
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A prospective evaluation of the utility of clinical breast examination
Published in Cancer research (Chicago, Ill.) (15-01-2009)“…Abstract Abstract #5012 Emphasis on mammography, and to a lesser extent MRI, for breast cancer screening, is temporally associated with decreased practice of…”
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Measurement of DNA copy number at microsatellite loci using quantitative PCR analysis
Published in Cancer research (Chicago, Ill.) (01-10-2000)“…This report describes the development and validation of quantitative microsatellite analysis (QuMA) for rapid measurement of relative DNA sequence copy number…”
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Accumulation of p53 tumor suppressor gene protein: an independent marker of prognosis in breast cancers
Published in JNCI : Journal of the National Cancer Institute (03-06-1992)“…Mutations of the tumor suppressor gene p53 have been identified in breast cancer cell lines, and some breast carcinomas are detectable by immunohistochemical…”
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In utero angiopoietin-2 gene delivery remodels placental blood vessel phenotype: a murine model for studying placental angiogenesis
Published in Molecular human reproduction (01-04-2005)“…Angiopoietin (Ang)-2, the natural antagonist of the Ang1/Tie2 receptor is a complex regulator of blood vessel plasticity that plays a pivotal role in both…”
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Effect of cooking time and temperature on the heterocyclic amine content of fried beef patties
Published in Food and chemical toxicology (1994)“…The mutagenic heterocyclic amines 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), 2-amino-3-methylimidazo[4,5-f]quinoline (IQ),…”
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The Importance of Age and Smoking in Evaluating Adverse Cytogenetic Effects of Exposure to Environmental Agents
Published in Environmental Health Perspectives. 1996 (01-05-1996)“…Fluorescence in situ hybridization with chromosome-specific composite DNA probes (chromosome painting) is a reliable and efficient method for detecting…”
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Radiation-Induced Translocations in Mice: Persistence, Chromosome Specificity, and Influence of Genetic Background
Published in Radiation research (01-09-2000)“…The translocation frequency response in the chromosomes of peripheral blood lymphocytes is widely used for radiation biomonitoring and dose estimation…”
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Multi-endpoint biological monitoring of phosphine workers
Published in Mutation research (20-04-2003)“…The pesticide phosphine (PH 3) is a suspected carcinogen and a known clastogen which has been shown to produce chromosome damage in agricultural workers. To…”
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Persistence of radiation-induced translocations in rat peripheral blood determined by chromosome painting
Published in Environmental and molecular mutagenesis (1997)“…In this article, we address the issue of persistence of chromosome exchanges following acute in vitro exposure of rat peripheral blood to 137Cs. Irradiation…”
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Persistence of aneuploid immature/primitive hemopoietic sub-populations in mice 8 months after benzene exposure in vivo
Published in Mutation research (05-04-2001)“…Benzene (bz) is a common environmental contaminant associated with increased risk of myeloid leukemia. Chronic bz exposure in vivo increases the frequency of…”
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Dermal benzene and trichloroethylene induce aneuploidy in immature hematopoietic subpopulations in vivo
Published in Environmental and molecular mutagenesis (2001)“…Accumulation of genetic damage in long‐lived cell populations with proliferative capacity is implicated in tumorigenesis. Hematopoietic stem cells (hsc)…”
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Case-control study of malignant melanoma among employees of the Lawrence Livermore national laboratory
Published in American journal of industrial medicine (01-10-1997)“…During 1972 to 1977, the Lawrence Livermore National Laboratory (LLNL) experienced increased diagnosis of malignant melanoma among employees. In 1984, a report…”
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Micronuclei induced in round spermatids of mice after stem-cell treatment with chloral hydrate: Evaluations with centromeric DNA probes and kinetochore antibodies
Published in Environmental and molecular mutagenesis (1996)“…The chromosomal effects of chloral hydrate (CH) on germ cells of male mice were investigated using two methods to detect and characterize spermatid micronuclei…”
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Cutaneous Melanoma at Lawrence Livermore National Laboratory: Comparison with Rates in Two San Francisco Bay Area Counties
Published in Cancer causes & control (01-05-1992)“…During the period 1974 through 1985, employees at Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States) were diagnosed with cutaneous…”
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Comparison of cellular and whole-animal bioassays for estimation of radiation effects in the polychaete worm Neanthes arenaceodentata (Polychaeta)
Published in Archives of environmental contamination and toxicology (01-03-1990)“…The polychaete worm Neanthes arenaceodentata was used in experiments to determine possible relationships between short-term genotoxicity tests and reproductive…”
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