Search Results - "Moore, Tara L"

Distribution and overlap of entorhinal, premotor, and amygdalar connections in the monkey anterior cingulate cortex by Calderazzo, Samantha M., Busch, Silas E., Moore, Tara L., Rosene, Douglas L., Medalla, Maria

“…The anterior cingulate cortex (ACC) is important for decision‐making as it integrates motor plans with affective and contextual limbic information. Disruptions…”
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Extracellular Vesicle Treatment Alleviates Neurodevelopmental and Neurodegenerative Pathology in Cortical Spheroid Model of Down Syndrome by Campbell, Natalie Baker, Patel, Yesha, Moore, Tara L, Medalla, Maria, Zeldich, Ella

“…Down syndrome (DS), or trisomy 21, is manifested in a variety of anatomical and cellular abnormalities resulting in intellectual deficits and early onset of…”
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T Cells Actively Infiltrate the White Matter of the Aging Monkey Brain in Relation to Increased Microglial Reactivity and Cognitive Decline by Batterman, Katelyn V, Cabrera, Payton E, Moore, Tara L, Rosene, Douglas L

“…Normal aging is characterized by declines in processing speed, learning, memory, and executive function even in the absence of neurodegenerative diseases such…”
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Dysregulated C1q and CD47 in the aging monkey brain: association with myelin damage, microglia reactivity, and cognitive decline by DeVries, Sarah A, Dimovasili, Christina, Medalla, Maria, Moore, Tara L, Rosene, Douglas L

“…Normal aging, though lacking widespread neurodegeneration, is nevertheless characterized by cognitive impairment in learning, memory, and executive function…”
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Mesenchymal-derived extracellular vesicles enhance microglia-mediated synapse remodeling after cortical injury in aging Rhesus monkeys by Zhou, Yuxin, Bhatt, Hrishti, Mojica, Chromewell A, Xin, Hongqi, Pessina, Monica A, Rosene, Douglas L, Moore, Tara L, Medalla, Maria

“…Understanding the microglial neuro-immune interactions in the primate brain is vital to developing therapeutics for cortical injury, such as stroke or…”
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The use of hydrogel-delivered extracellular vesicles in recovery of motor function in stroke: a testable experimental hypothesis for clinical translation including behavioral and neuroimaging assessment approaches by Tsintou, Magdalini, Dalamagkas, Kyriakos, Moore, Tara, Rathi, Yogesh, Kubicki, Marek, Rosene, Douglas, Makris, Nikos

“…Neural tissue engineering, nanotechnology and neuroregeneration are diverse biomedical disciplines that have been working together in recent decades to solve…”
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Human-to-monkey transfer learning identifies the frontal white matter as a key determinant for predicting monkey brain age by He, Sheng, Guan, Yi, Cheng, Chia Hsin, Moore, Tara L, Luebke, Jennifer I, Killiany, Ronald J, Rosene, Douglas L, Koo, Bang-Bon, Ou, Yangming

“…The application of artificial intelligence (AI) to summarize a whole-brain magnetic resonance image (MRI) into an effective "brain age" metric can provide a…”
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The Effects of a Novel Non-catechol Dopamine Partial Agonist on Working Memory in the Aged Rhesus Monkey by Moore, Tara L, Young, Damon A, Killiany, Ronald J, Fonseca, Kari R, Volfson, Dmitri, Gray, David L, Balice-Gordon, Rita, Kozak, Rouba

“…Aged-related declines in cognition, especially working memory and executive function, begin in middle-age and these abilities are known to be mediated by the…”
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Sex differences in recovery of motor function in a rhesus monkey model of cortical injury by Bottenfield, Karen R, Bowley, Bethany G E, Pessina, Monica A, Medalla, Maria, Rosene, Douglas L, Moore, Tara L

“…Stroke disproportionately affects men and women, with women over 65 years experiencing increased severity of impairment and higher mortality rates than men…”
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Neural recovery after cortical injury: Effects of MSC derived extracellular vesicles on motor circuit remodeling in rhesus monkeys by Calderazzo, Samantha, Covert, Margaret, Alba, Diego De, Bowley, Bethany E., Pessina, Monica A., Rosene, Douglas L., Buller, Benjamin, Medalla, Maria, Moore, Tara L.

“…Reorganization of motor circuits in the cortex and corticospinal tract are thought to underlie functional recovery after cortical injury, but the mechanisms of…”
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Exosomes derived from bone marrow mesenchymal stromal cells promote remyelination and reduce neuroinflammation in the demyelinating central nervous system by Zhang, Jing, Buller, Benjamin A., Zhang, Zheng Gang, Zhang, Yi, Lu, Mei, Rosene, Douglas L., Medalla, Maria, Moore, Tara L., Chopp, Michael

“…Injury of oligodendrocytes (OLs) induces demyelination, and patients with neurodegenerative diseases exhibit demyelination concomitantly with neurological…”
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Effects on Executive Function Following Damage to the Prefrontal Cortex in the Rhesus Monkey (Macaca mulatta) by Moore, Tara L, Schettler, Stephen P, Killiany, Ronald J, Rosene, Douglas L, Moss, Mark B

“…Executive function is a term used to describe the cognitive processes subserved by the prefrontal cortex (PFC). An extensive body of work has characterized the…”
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Treatment with Mesenchymal-Derived Extracellular Vesicles Reduces Injury-Related Pathology in Pyramidal Neurons of Monkey Perilesional Ventral Premotor Cortex by Medalla, Maria, Chang, Wayne, Calderazzo, Samantha M, Go, Veronica, Tsolias, Alexandra, Goodliffe, Joseph W, Pathak, Dhruba, De Alba, Diego, Pessina, Monica, Rosene, Douglas L, Buller, Benjamin, Moore, Tara L

“…Functional recovery after cortical injury, such as stroke, is associated with neural circuit reorganization, but the underlying mechanisms and efficacy of…”
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Neuroanatomical Substrates of Circuit-Specific Cholinergic Modulation across the Primate Anterior Cingulate Cortex by Tsolias, Alexandra, Zhou, Yuxin, Mojica, Chromewell A, Sakharkar, Mitali, Tsolias, Marianna Z, Moore, Tara L, Rosene, Douglas L, Medalla, Maria

“…Acetylcholine is a robust neuromodulator of the limbic system and a critical regulator of arousal and emotions. The anterior cingulate cortex (ACC) and the…”
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Computerized Adaptive Tests for Rapid and Accurate Assessment of Psychopathology Dimensions in Youth by Gibbons, Robert D., Kupfer, David J., Frank, Ellen, Lahey, Benjamin B., George-Milford, Brandie A., Biernesser, Candice L., Porta, Giovanna, Moore, Tara L., Kim, Jong Bae, Brent, David A.

“…At least half of youths with mental disorders are unrecognized and untreated. Rapid, accurate assessment of child mental disorders could facilitate…”
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Prefrontal and Medial Temporal Interactions in Memory Functions in the Rhesus Monkey by Welke, Laura A., Moore, Tara L., Rosene, Douglas L., Killiany, Ronald J., Moss, Mark B.

“…Both the medial temporal lobe and the dorsolateral prefrontal cortex have been implicated in learning and memory. However, it has been difficult to ascertain…”
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Curcumin Improves Reversal Learning in Middle-Aged Rhesus Monkeys by Uprety, Ajay, Moss, Mark B., Rosene, Douglas L., Killiany, Ronald J., Moore, Tara L.

“…Age-related impairments in cognitive function occur in multiple animal species including humans and nonhuman primates. Humans and rhesus monkeys exhibit a…”
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Layer-specific pyramidal neuron properties underlie diverse anterior cingulate cortical motor and limbic networks by Medalla, Maria, Chang, Wayne, Ibañez, Sara, Guillamon-Vivancos, Teresa, Nittmann, Mathias, Kapitonava, Anastasia, Busch, Silas E, Moore, Tara L, Rosene, Douglas L, Luebke, Jennifer I

“…Abstract The laminar cellular and circuit mechanisms by which the anterior cingulate cortex (ACC) exerts flexible control of motor and affective information…”
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Extracellular vesicles derived from bone marrow mesenchymal stem cells enhance myelin maintenance after cortical injury in aged rhesus monkeys by Go, Veronica, Sarikaya, Deniz, Zhou, Yuxin, Bowley, Bethany G.E., Pessina, Monica A., Rosene, Douglas L., Zhang, Zheng Gang, Chopp, Michael, Finklestein, Seth P., Medalla, Maria, Buller, Benjamin, Moore, Tara L.

“…Cortical injury, such as stroke, causes neurotoxic cascades that lead to rapid death and/or damage to neurons and glia. Axonal and myelin damage in particular,…”
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Fatigue microdamage in bovine trabecular bone by Moore, Tara L, Gibson, Lorna J

“…Microdamage, in the form of small cracks, may accumulate in trabecular bone loaded in fatigue. Specimens of bovine trabecular bone were loaded in compressive…”
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