Search Results - "Moore, Stephen P.G."

YAP facilitates melanoma migration through regulation of actin‐related protein 2/3 complex subunit 5 (ARPC5) by Lui, Jason W., Moore, Stephen P.G., Huang, Lee, Ogomori, Kelsey, Li, Yan, Lang, Deborah

“…Yes‐associated protein 1 (YAP) and transcriptional coactivator with PDZ‐binding motif (TAZ) are transcriptional coactivators that have been implicated in…”
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Targeting Pan-ETS Factors Inhibits Melanoma Progression by Huang, Lee, Zhai, Yougang, La, Jennifer, Lui, Jason W, Moore, Stephen P G, Little, Elizabeth C, Xiao, Sixia, Haresi, Adil J, Brem, Candice, Bhawan, Jag, Lang, Deborah

“…The failure of once promising target-specific therapeutic strategies often arises from redundancies in gene expression pathways. Even with new melanoma…”
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Transcription Factors and DNA Repair Enzymes Compete for Damaged Promoter Sites by Moore, Stephen P.G., Kruchten, Joshua, Toomire, Kimberly J., Strauss, Phyllis R.

“…Transcriptional regulation is a tightly regulated, vital process. The transcription factor cyclic AMP-response element-binding protein 1 (CREB1) controls ∼25%…”
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DNA modifications repaired by base excision repair are epigenetic by Moore, Stephen P.G., Toomire, Kimberly J., Strauss, Phyllis R.

“…•Oxidative DNA damage and uracil are repaired by base excision repair (BER).•CREB regulates ∼25% of the eukaryotic transcriptome.•Damage repaired by BER…”
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DNA Damage Repaired by the Base Excision Repair Pathway Is Epigenetic by Strauss, Phyllis R, Toomire, Kim, Moore, Stephen P.G.

“…Abstract only Many of the enzymes involved in BER are embryonic lethals and at least one (AP endonuclease1) controls protein levels of the critical…”
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