Search Results - "Moore, Sara R"
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Hijacking Factor H for Complement Immune Evasion
Published in Frontiers in immunology (25-02-2021)“…The complement system is an essential player in innate and adaptive immunity. It consists of three pathways (alternative, classical, and lectin) that initiate…”
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A novel assay that characterizes properdin function shows neutrophil-derived properdin has a distinct oligomeric distribution
Published in Frontiers in immunology (12-01-2023)“…Properdin acts as an essential positive regulator of the alternative pathway of complement by stabilizing enzymatic convertases. Identical properdin monomers…”
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A Case of Cutaneous Vasculitis in the Setting of Systemic Lupus Erythematosus and Cocaine Use
Published in JIM - high impact case reports (01-01-2023)“…Cocaine, one of most prevalent illicit substances in the United States, affects a multitude of organ systems and precedes numerous negative health outcomes…”
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Factor H preserves alternative complement function during ARDS, linked to improved survival
Published in ERJ open research (01-05-2023)“…Effective regulation of complement activation may be crucial to preserving complement function during acute respiratory distress syndrome (ARDS). Factor H is…”
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Increased Alternative Complement Pathway Function and Improved Survival during Critical Illness
Published in American journal of respiratory and critical care medicine (15-07-2020)“…Complement is crucial for host defense but may also drive dysregulated inflammation. There is limited understanding of alternative complement function, which…”
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Systematic Review of the Clinical Characteristics and Management of Isaac Syndrome
Published in Journal of clinical neuromuscular disease (01-12-2023)“…Abstract Objectives: Isaac syndrome (IS) is a condition characterized by peripheral nerve hyperexcitability caused by voltage-gated potassium channel…”
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Journal Article -
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Assessment of function of neutrophil-derived properdin in a novel functional assay
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract The alternative pathway (AP) of complement is an essential immune effector mechanism. Properdin (P), the only positive regulator of the AP, is…”
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Journal Article -
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Literacy Through Photography: Third-Year and Beyond, First-Generation College Student Experience with Culture and Academic Discourse
Published 01-01-2015“…This qualitative portraiture study examines current issues that surround the experience of third-year and beyond, first-generation college students. There is a…”
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Dissertation