Search Results - "Moore, Mary Courtney"
-
1
Regulation of Hepatic Glucose Uptake and Storage In Vivo
Published in Advances in nutrition (Bethesda, Md.) (01-05-2012)“…In the postprandial state, the liver takes up and stores glucose to minimize the fluctuation of glycemia. Elevated insulin concentrations, an increase in the…”
Get full text
Journal Article -
2
Molecular engineering of safe and efficacious oral basal insulin
Published in Nature communications (27-07-2020)“…Recently, the clinical proof of concept for the first ultra-long oral insulin was reported, showing efficacy and safety similar to subcutaneously administered…”
Get full text
Journal Article -
3
Glucagon's effect on liver protein metabolism in vivo
Published in American journal of physiology: endocrinology and metabolism (01-09-2017)“…The postprandial state is characterized by a storage of nutrients in the liver, muscle, and adipose tissue for later utilization. In the case of a protein-rich…”
Get more information
Journal Article -
4
Author Correction: Molecular engineering of safe and efficacious oral basal insulin
Published in Nature communications (20-08-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
Get full text
Journal Article -
5
Chronic consumption of a high-fat/high-fructose diet renders the liver incapable of net hepatic glucose uptake
Published in American journal of physiology: endocrinology and metabolism (01-12-2010)“…The objective of this study was to assess the response of a large animal model to high dietary fat and fructose (HFFD). Three different metabolic assessments…”
Get more information
Journal Article -
6
Chronic overeating impairs hepatic glucose uptake and disposition
Published in American journal of physiology: endocrinology and metabolism (15-05-2015)“…Dogs consuming a hypercaloric high-fat and -fructose diet (52 and 17% of total energy, respectively) or a diet high in either fructose or fat for 4 wk…”
Get more information
Journal Article -
7
C-peptide enhances glucagon secretion in response to hyperinsulinemia under euglycemic and hypoglycemic conditions
Published in JCI insight (22-06-2021)“…Several studies have associated the presence of residual insulin secretion capability (also referred to as being C-peptide positive) with lower risk of…”
Get full text
Journal Article -
8
Pregnancy augments hepatic glucose storage in response to a mixed meal
Published in British journal of nutrition (28-02-2012)“…Studies were carried out on conscious female non-pregnant (NP) and pregnant (P; third-trimester) dogs (n 16; eight animals per group) to define the role of the…”
Get full text
Journal Article -
9
Diet-induced impaired glucose tolerance and gestational diabetes in the dog
Published in Journal of applied physiology (1985) (01-02-2011)“…Glucose metabolism was compared in dogs consuming a chow/meat diet throughout pregnancy (P group, n = 6) and dogs switched to a high-fat/high-fructose (HFF)…”
Get full text
Journal Article -
10
Hepatic Glycogen Supercompensation Activates AMP-Activated Protein Kinase, Impairs Insulin Signaling, and Reduces Glycogen Deposition in the Liver
Published in Diabetes (New York, N.Y.) (01-02-2011)“…The objective of this study was to determine how increasing the hepatic glycogen content would affect the liver's ability to take up and metabolize glucose…”
Get full text
Journal Article -
11
Acute Fructose Administration Improves Oral Glucose Tolerance in Adults With Type 2 Diabetes
Published in Diabetes care (01-11-2001)“…Acute Fructose Administration Improves Oral Glucose Tolerance in Adults With Type 2 Diabetes Mary Courtney Moore , PHD 1 , Stephen N. Davis , MD 1 2 3 ,…”
Get full text
Journal Article -
12
Insulin secretion-independent effects of GLP-1 on canine liver glucose metabolism do not involve portal vein GLP-1 receptors
Published in American journal of physiology: Gastrointestinal and liver physiology (01-11-2005)“…Whether glucagon-like peptide (GLP)-1 requires the hepatic portal vein to elicit its insulin secretion-independent effects on glucose disposal in vivo was…”
Get more information
Journal Article -
13
Direct and Indirect Effects of Insulin on Glucose Uptake and Storage by the Liver
Published in Diabetes (New York, N.Y.) (01-06-2002)“…Direct and Indirect Effects of Insulin on Glucose Uptake and Storage by the Liver Shosuke Satake , Mary Courtney Moore , Kayano Igawa , Margaret Converse ,…”
Get full text
Journal Article -
14
Effect of hepatic denervation on peripheral insulin sensitivity in conscious dogs
Published in American journal of physiology: endocrinology and metabolism (01-02-2002)“…We tested the hypothesis that the loss of hepatic nerves decreases peripheral insulin sensitivity. Surgical hepatic denervation (DN) was performed in 22 dogs…”
Get more information
Journal Article -
15
Portal infusion of amino acids is more efficient than peripheral infusion in stimulating liver protein synthesis at the same hepatic amino acid load in dogs
Published in The American journal of clinical nutrition (01-10-2008)“…BACKGROUND: Hepatic glucose uptake is enhanced by the portal delivery of glucose, which creates a negative arterioportal substrate gradient. Hepatic amino acid…”
Get full text
Journal Article -
16
Regulation of hepatic and peripheral glucose disposal
Published in Baillière's best practice & research. Clinical endocrinology & metabolism (01-09-2003)“…Precise regulation of hepatic and peripheral glucose uptake is essential to preserve glucose homeostasis. The liver extracts ∼1/3 of an oral glucose load,…”
Get full text
Journal Article -
17
Effect of intraportal glucagon-like peptide-1 on glucose metabolism in conscious dogs
Published in American journal of physiology: endocrinology and metabolism (01-05-2003)“…Arteriovenous difference and tracer ([3-(3)H]glucose) techniques were used in 42-h-fasted conscious dogs to identify any insulin-like effects of intraportally…”
Get more information
Journal Article -
18
Hepatic and muscle insulin action during late pregnancy in the dog
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-01-2007)“…We evaluated the effects of physiologic increases in insulin on hepatic and peripheral glucose metabolism in nonpregnant (NP) and pregnant (P; 3rd trimester)…”
Get more information
Journal Article -
19
Inclusion of Low Amounts of Fructose With an Intraduodenal Glucose Load Markedly Reduces Postprandial Hyperglycemia and Hyperinsulinemia in the Conscious Dog
Published in Diabetes (New York, N.Y.) (01-02-2002)“…Inclusion of Low Amounts of Fructose With an Intraduodenal Glucose Load Markedly Reduces Postprandial Hyperglycemia and Hyperinsulinemia in the Conscious Dog…”
Get full text
Journal Article -
20
Portal Serotonin Infusion and Glucose Disposal in Conscious Dogs
Published in Diabetes (New York, N.Y.) (01-01-2004)“…Portal Serotonin Infusion and Glucose Disposal in Conscious Dogs Mary Courtney Moore 1 , W. Blair Geho 2 , Margaret Lautz 1 , Ben Farmer 1 , Doss W. Neal 1 and…”
Get full text
Journal Article