Search Results - "Moore, John"
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Cytokine release syndrome in severe COVID-19
Published in Science (American Association for the Advancement of Science) (01-05-2020)“…Lessons from arthritis and cell therapy in cancer patients point to therapy for severe disease In December 2019, a new strain of coronavirus, severe acute…”
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Approaches for Optimal Use of Different COVID-19 Vaccines: Issues of Viral Variants and Vaccine Efficacy
Published in JAMA : the journal of the American Medical Association (06-04-2021)“…This Viewpoint proposes ways to maximize vaccine efficacy and allocation given the rise of coronavirus variants and authorization of a Johnson & Johnson…”
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SARS-CoV-2 Vaccines and the Growing Threat of Viral Variants
Published in JAMA : the journal of the American Medical Association (02-03-2021)“…This Viewpoint reviews circulating SARS-CoV-2 genetic variants and mechanisms of immunity by which they might escape coronavirus vaccine-induced protection and…”
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Predicting tipping points in complex environmental systems
Published in Proceedings of the National Academy of Sciences - PNAS (23-01-2018)Get full text
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Belowground community responses to fire: meta‐analysis reveals contrasting responses of soil microorganisms and mesofauna
Published in Oikos (01-03-2019)“…Global fire regimes are shifting due to climate and land use changes. Understanding the responses of belowground communities to fire is key to predicting…”
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Antimicrobial Resistance (AMR)
Published in British journal of biomedical science (28-06-2023)“…Antimicrobial resistance (AMR) has now emerged as a chronic public health problem globally, with the forecast of 10 million deaths per year globally by 2050…”
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Recent advances in carbon emissions reduction: policies, technologies, monitoring, assessment and modeling
Published in Journal of cleaner production (15-09-2015)“…Climate change and its social, environmental, economic and ethical consequences are widely recognized as the major set of interconnected problems facing human…”
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Trends in U.S. Cardiovascular Care: 2016 Report from 4 ACC National Cardiovascular Data Registries
Published in Journal of the American College of Cardiology (21-03-2017)“…Abstract Cardiovascular disease (CVD) is a leading cause of death and disability in the United States. National quality programs such as the National…”
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Native‐like Env trimers as a platform for HIV‐1 vaccine design
Published in Immunological reviews (01-01-2017)“…Summary We describe the development and potential use of various designs of recombinant HIV‐1 envelope glycoprotein trimers that mimic the structure of the…”
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Bone marrow-derived and resident liver macrophages display unique transcriptomic signatures but similar biological functions
Published in Journal of hepatology (01-10-2016)“…Graphical abstract…”
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Dependence of the evolution of carbon dynamics in the northern permafrost region on the trajectory of climate change
Published in Proceedings of the National Academy of Sciences - PNAS (10-04-2018)“…We conducted a model-based assessment of changes in permafrost area and carbon storage for simulations driven by RCP4.5 and RCP8.5 projections between 2010 and…”
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COVID-19 Vaccines: "Warp Speed" Needs Mind Melds, Not Warped Minds
Published in Journal of virology (17-08-2020)“…In this review, we address issues that relate to the rapid "Warp Speed" development of vaccines to counter the COVID-19 pandemic. We review the antibody…”
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Virus vaccines: proteins prefer prolines
Published in Cell host & microbe (10-03-2021)“…Most viral vaccines are based on inducing neutralizing antibodies (NAbs) against the virus envelope or spike glycoproteins. Many viral surface proteins exist…”
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Diseases with health disparities as drivers of COVID‐19 outcome
Published in Journal of cellular and molecular medicine (01-10-2020)“…The COVID‐19 pandemic has forced our society to come face to face with complex issues that were once theoretical but are now being played out in real time. As…”
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Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers
Published in Immunity (Cambridge, Mass.) (15-05-2014)“…All previously characterized broadly neutralizing antibodies to the HIV-1 envelope glycoprotein (Env) target one of four major sites of vulnerability. Here, we…”
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The re-imagining of a framework for agricultural land use: A pathway for integrating agricultural practices into ecosystem services, planetary boundaries and sustainable development goals: This article belongs to Ambio’s 50th Anniversary Collection. Theme: Agricultural land use
Published in Ambio (01-07-2021)“…This paper reflects on the legacy of the Ambio papers by Sombroek et al. (1993), Turner et al. (1994), and Brussaard et al. (1997) on the study of agricultural…”
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Projected Atlantic hurricane surge threat from rising temperatures
Published in Proceedings of the National Academy of Sciences - PNAS (02-04-2013)“…Detection and attribution of past changes in cyclone activity are hampered by biased cyclone records due to changes in observational capabilities. Here, we…”
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Root cap–derived cells and mucilage: a protective network at the root tip
Published in Protoplasma (01-11-2021)“…Root cap–derived cells and mucilage provide the first line of defense of the plant against soil microbial pathogens. These cells form a mucilaginous root…”
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Fetal Membranes, Not a Mere Appendage of the Placenta, but a Critical Part of the Fetal-Maternal Interface Controlling Parturition
Published in Obstetrics and gynecology clinics of North America (01-03-2020)“…Fetal membranes (FMs) play a role in pregnancy maintenance and promoting parturition at term. The FMs are not just part of the placenta, structurally or…”
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A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies
Published in PLoS pathogens (01-09-2013)“…A desirable but as yet unachieved property of a human immunodeficiency virus type 1 (HIV-1) vaccine candidate is the ability to induce broadly neutralizing…”
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