Search Results - "Moore, Jeffrey P."

MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activity by Weber, Martina, Baker, Meredith B., Moore, Jeffrey P., Searles, Charles D.

“…Mechanical forces associated with blood flow play an important role in regulating vascular signaling and gene expression in endothelial cells (ECs). MicroRNAs…”
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Reversal of Vascular Macrophage Accumulation and Hypertension by a CCR2 Antagonist in Deoxycorticosterone/Salt-Treated Mice by Chan, Christopher T, Moore, Jeffrey P, Budzyn, Klaudia, Guida, Elizabeth, Diep, Henry, Vinh, Antony, Jones, Emma S, Widdop, Robert E, Armitage, James A, Sakkal, Samy, Ricardo, Sharon D, Sobey, Christopher G, Drummond, Grant R

“…Infiltration of macrophages into the artery wall plays detrimental roles during hypertension by promoting vascular inflammation and endothelial dysfunction,…”
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Statin Treatment and 3′ Polyadenylation of eNOS mRNA by Kosmidou, Ioanna, Moore, Jeffrey P, Weber, Martina, Searles, Charles D

“…OBJECTIVE—Statins have been shown to increase endothelial nitric oxide synthase expression via enhanced mRNA stability. Because the poly(A) tail is an…”
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Immune Cell Infiltration in Malignant Middle Cerebral Artery Infarction: Comparison with Transient Cerebral Ischemia by Chu, Hannah X, Kim, Hyun Ah, Lee, Seyoung, Moore, Jeffrey P, Chan, Christopher T, Vinh, Antony, Gelderblom, Mathias, Arumugam, Thiruma V, Broughton, Brad RS, Drummond, Grant R, Sobey, Christopher G

“…We tested whether significant leukocyte infiltration occurs in a mouse model of permanent cerebral ischemia. C57BL6/J male mice underwent either permanent (3…”
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M2 macrophage accumulation in the aortic wall during angiotensin II infusion in mice is associated with fibrosis, elastin loss, and elevated blood pressure by Moore, Jeffrey P, Vinh, Antony, Tuck, Kellie L, Sakkal, Samy, Krishnan, Shalini M, Chan, Christopher T, Lieu, Maggie, Samuel, Chrishan S, Diep, Henry, Kemp-Harper, Barbara K, Tare, Marianne, Ricardo, Sharon D, Guzik, Tomasz J, Sobey, Christopher G, Drummond, Grant R

“…Macrophages accumulate in blood vessels during hypertension. However, their contribution to vessel remodeling is unknown. In the present study, we examined the…”
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Laminar Shear Stress Modulates Phosphorylation and Localization of RNA Polymerase II on the Endothelial Nitric Oxide Synthase Gene by Moore, Jeffrey P, Weber, Martina, Searles, Charles D

“…OBJECTIVE—In endothelial cells exposed to unidirectional laminar shear stress, endothelial nitric oxide synthase transcription (eNOS), mRNA stability, and…”
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A flow cytometric method for the analysis of macrophages in the vascular wall by Moore, Jeffrey P., Sakkal, Samy, Bullen, Michelle L., Kemp-Harper, Barbara K., Ricardo, Sharon D., Sobey, Christopher G., Drummond, Grant R.

“…Macrophages accumulate in the vascular wall during conditions such as hypertension and hypercholesterolemia and contribute to vascular remodelling. Here we…”
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63 M2 MACROPHAGE POLARIZATION AS A CAUSE OF VASCULARFIBROSIS AND STIFFENING IN HYPERTENSION by Moore, Jeffrey P, Sakkal, Samy, Ricardo, Sharon L, Vinh, Antony, Gaspari, Tracey, Kemp-Harper, Barbara, Sobey, Christopher G, Drummond, Grant R

“…BACKGROUND:Arterial stiffening is a hallmark of hypertension and contributes to elevated systolic blood pressure (SBP), increased cardiac afterload, poor…”
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Testing the hypothesis that locus coeruleus hyperactivity produces depression-related changes via galanin by Weiss, Jay M., Boss-Williams, Katherine A., Moore, Jeffrey P., Demetrikopoulos, Melissa K., Ritchie, James C., West, Charles H.K.

“…This paper reviews progress made in testing the idea that depression-related behavioral changes can arise from hyperactivity of locus coeruleus (LC) neurons…”
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The Practice of Polydoxy in Polyrepresentational Parishes by Moore, Jeffrey P

“…This project explores theological multiplicity within multi-denominational congregations. Pastors of Local Ecumenical Partnerships (England) and Federated or…”
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Abstract 455: M2 Macrophages Contribute to Vessel Fibrosis and Stiffening During Angiotensin II-Dependent Hypertension in Mice by Drummond, Grant R, Moore, Jeffrey P, Tuck, Kellie L, Sakkal, Samy, Krishnan, Shalini M, Diep, Henry, Kemp-Harper, Barbara K, Budzyn, Klaudia, Ricardo, Sharon D, Guzik, Tomasz J, Samuel, Chrishan S, Sobey, Christopher G

“…Abstract only Arterial fibrosis and stiffening are hallmarks of hypertension and contribute to elevated systolic blood pressure (BP), heart failure and end…”
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Abstract 448: A CCR2 Anatagonist Reduces Vascular Fibrosis, Macrophage Accumulation and Blood Pressure in Angiotensin II-Treated Mice by Drummond, Grant R, Moore, Jeffrey P, Sakkal, Samy, Krishnan, Shalini M, Samuel, Chrishan S, Diep, Henry, Kemp-Harper, Barbara K, Vinh, Antony, Ricardo, Sharon L, Guzik, Tomasz J, Sobey, Christopher G

“…Abstract only Macrophages accumulate in the vascular wall during hypertension. However, their contribution to vascular remodeling remains to be established. In…”
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17 CHEMOKINE RECEPTORS AS NOVEL PHARMACOLOGICAL TARGETS TO REDUCE BLOOD PRESSURE DURING EXPERIMENTAL HYPERTENSION IN MICE by Chan, Christopher T, Moore, Jeffrey P, Budzyn, Klaudia, Vinh, Antony, Jones, Emma S, Sobey, Christopher G, Drummond, Grant R

“…INTRODUCTION & AIMS:Leukocyte infiltration into the artery wall plays a pathophysiological role in hypertension by promoting vascular inflammation and…”
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Abstract 255: Laminar Shear Stress Enhances the Activity and Localization of RNA Polymerase II on the eNOS Gene by Weber, Martina, Moore, Jeffrey P, Searles, Charles D

“…Abstract only We have previously found that laminar shear enhances eNOS mRNA stability and translation by altering endothelial NO synthase (eNOS) mRNA 3′…”
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The flood at the foot of the classroom door: Secondary mathematics and English teachers describe data-driven decision making by Moore, Jeffrey P

“…PROBLEM: Data-driven decision making has been a focus of school reform efforts for decades. As new testing and teacher evaluation regimes take hold, the focus…”
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ESOPHAGEAL MONILIASIS: A REVIEW OF COMMON AND LESS FREQUENT CHARACTERISTICS by LEWICKI, ANN M, MOORE, JEFFREY P

“…Invasion of the esophagus by Candida albicans probably occurs more frequently than the reported cases suggest. The disease usually occurs following…”
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The flood at the foot of the classroom door: Secondary mathematics and English teachers describe data-driven decision making by Moore, Jeffrey P

“…PROBLEM: Data-driven decision making has been a focus of school reform efforts for decades. As new testing and teacher evaluation regimes take hold, the focus…”
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Routine noninvasive hysterography in the evaluation and treatment of endometrial carcinoma by Anderson, B, Marchant, D J, Munzenrider, J E, Moore, J P, Mitchell, Jr, G W

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