Search Results - "Moore, Jeffrey A"
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Methods to evaluate the impact of SARS-CoV-2 nucleocapsid mutations on antigen detection by rapid diagnostic tests
Published in BioTechniques (01-09-2022)“…Mutations in the nucleocapsid of SARS-CoV-2 may interfere with antigen detection by diagnostic tests. We used several methods to evaluate the effect of various…”
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2
Intraoperative CT Scan Verification of Pedicle Screw Placement in AIS to Prevent Malpositioned Screws: Safety Benefit and Cost
Published in Spine deformity (01-11-2018)“…Prospective database review. Determine if use of intraoperative 3D imaging of pedicle screw position provides clinical and cost benefit. Injury or reoperation…”
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3
Risk of Injury to Retroperitoneal Structures in Prone and Lateral Decubitus Transpsoas Approaches to Lumbar Interbody Fusion: A Pilot Cadaveric Anatomical Study
Published in Curēus (Palo Alto, CA) (11-07-2023)“…Introduction The retroperitoneal approach for lateral lumbar interbody fusion (LLIF) originally described an initial posterolateral fascial incision enabling…”
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4
Quenching of Biotinylated Aequorin Bioluminescence by Dye-Labeled Avidin Conjugates: Application to Homogeneous Bioluminescence Resonance Energy Transfer Assays
Published in Organic letters (14-06-2001)“…Avidin conjugates containing the covalently attached dyes QSY-7 and dabcyl were prepared and shown to quench the bioluminescence of biotinylated aequorin…”
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5
Escherichia coli Dimethylallyl Diphosphate:tRNA Dimethylallyltransferase: A Binding Mechanism for Recombinant Enzyme
Published in Biochemistry (Easton) (21-01-1997)“…Escherichia coli dimethylallyl diphosphate:tRNA dimethylallyltransferase (DMAPP-tRNA transferase) catalyzes the first step in the biosynthesis of the…”
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Synthesis of a Chemiluminescent Acridinium Hydroxylamine (AHA) for the Direct Detection of Abasic Sites in DNA
Published in Organic letters (09-09-1999)“…The synthesis of a chemiluminescent acridinium hydroxylamine (AHA) for the direct detection of abasic sites in damaged nucleic acids is described. The reagent…”
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7
The value and cost-effectiveness of adult degenerative lumbar surgery
Published in Seminars in spine surgery (01-03-2014)“…Abstract Patients often seek surgical treatment for relief of their chronic lower back pain, generally caused by spinal stenosis, disc herniation, or…”
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Chemiluminescent acridinium-9-carboxamide boronic acid probes: Application to a homogeneous glycated hemoglobin assay
Published in Bioorganic & medicinal chemistry letters (01-03-2006)“…Chemiluminescent acridinium-9-carboxamide probes containing 1, 3, 9, and 27 phenylboronic acids were prepared and their chemiluminescent properties evaluated…”
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9
Application of Surface Plasmon Resonance toward Studies of Low-Molecular-Weight Antigen–Antibody Binding Interactions
Published in Methods (San Diego, Calif.) (01-03-2000)“…Methods for studying low-molecular-weight antigen–antibody binding interactions using surface plasmon resonance detection are presented. The experimental…”
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Regiodependent Luminescence Quenching of Biotinylated N-Sulfonyl-acridinium-9-carboxamides by Avidin
Published in Organic letters (16-10-2003)“…Biotin was conjugated to chemiluminescent N-sulfonylacridinium-9-carboxamides at the N-10 or 9-position carboxamide. Upon binding to avidin, the light output…”
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11
Chemiluminescence quenching of pteroic acid-N-sulfonyl-acridinium-9-carboxamide conjugates by folate binding protein
Published in Bioorganic & medicinal chemistry letters (03-05-2004)“…N(10)-Trifluoroacetylpteroic acid was conjugated to chemiluminescent N-sulfonylacridinium-9-carboxamide labels at the N(10) or 9-position carboxamide. Upon…”
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12
Dual Analyte Detection Using Tandem Flash Luminescence
Published in Bioorganic & medicinal chemistry letters (11-02-2002)“…A heterogeneous, dual analyte-binding assay which makes use of the flash luminescence from both aequorin and an acridinium-9-carboxamide label is presented…”
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Intrinsic factor-mediated modulation of cyanocobalamin– N-sulfonyl-acridinium-9-carboxamide chemiluminescence
Published in Bioorganic & medicinal chemistry letters (02-08-2004)“…Graphic Two cyanocobalamin– N-sulfonyl-acridinium-9-carboxamides with linkage through the N 10 or 9-position were prepared from B 12-e-carboxylic acid. The…”
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14
Chemoenzymatic Synthesis of 3‘-O-(Carboxyalkyl)fluorescein Labels
Published in Bioconjugate chemistry (01-05-1999)“…A general and versatile method is described for the synthesis of fluorescent labels. Coupling of the 3‘-phenol of fluorescein methyl ester with hydroxyalkyl…”
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O-(Fluoresceinylmethyl)hydroxylamine (OFMHA): A fluorescent reagent for detection of damaged nucleic acids
Published in Bioorganic & medicinal chemistry letters (15-12-1998)“…5- and 6- O-(Fluoresceinylmethyl)hydroxylamine (OFMHA, 5a, b) were prepared from the corresponding bis-pivaloyl-protected hydroxymethylfluoresceins ( 1a, b) in…”
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Immunoassay Reagents for Thyroid Testing. 3. Determination of the Solution Binding Affinities of a T4 Monoclonal Antibody Fab Fragment for a Library of Thyroxine Analogs Using Surface Plasmon Resonance
Published in Bioconjugate chemistry (1998)“…A library of thyroxine analogs and tracers was prepared, and their solution binding affinities for an anti-T4 Fab fragment were determined using a single…”
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Investigations into self-association of vancomycin covalent dimers using surface plasmon resonance technology
Published in Bioorganic & medicinal chemistry letters (16-08-1999)“…Covalent dimers of vancomycin linked through the vancosamine sugar moieties of the glycopeptide antibiotic have been synthesized in one step in 67–69% yield…”
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Design of Acridinium-9-carboxamides and Anti-acridinium Antibodies for Chemiluminescent Signal Enhancement
Published in Bioconjugate chemistry (01-05-2001)“…A novel system of signal enhancement is presented in which every labeled antibody is capable of generating a signal. Three chemiluminescent…”
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Evaluation of chemiluminescent estradiol conjugates by using a surface plasmon resonance detector
Published in Steroids (01-06-2000)“…A series of chemiluminescent 17β-estradiol probes were synthesized. Relative equilibrium dissociation constants ( K D) for the interaction of an anti-E 2 Fab…”
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Modulation of the chemiluminescent signal from N10-(3-sulfopropyl)- N-sulfonylacridinium-9-carboxamides
Published in Tetrahedron (01-09-1999)“…Acridinium salts 3a-h were synthesized from the corresponding sulfonamides 1a-h and their chemiluminescence profiles were compared. The quantity of light…”
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