Search Results - "Moore, Ian"
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Acoustic Emission Sensing of Pipe–Soil Interaction: Full-Scale Pipelines Subjected to Differential Ground Movements
Published in Journal of geotechnical and geoenvironmental engineering (01-12-2019)“…AbstractThis paper presents the first full-scale demonstration of the potential use of pipe–soil interaction-generated acoustic emission (AE) for early…”
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Experimental Investigation Examining Influence of Burial Depth on Stability of Horizontal Boreholes in Sand
Published in Journal of geotechnical and geoenvironmental engineering (01-05-2020)“…AbstractHorizontal directional drilling (HDD) is now widely used for pipe installation by the trenchless industry. Horizontal borehole stability under…”
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3
Enhanced inflammation in New Zealand white rabbits when MERS-CoV reinfection occurs in the absence of neutralizing antibody
Published in PLoS pathogens (01-08-2017)“…The Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic betacoronavirus that was first detected in humans in 2012 as a cause of severe acute…”
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4
The steroid-inducible pOp6/LhGR gene expression system is fast, sensitive and does not cause plant growth defects in rice (Oryza sativa)
Published in BMC plant biology (09-10-2021)“…Inducible systems for transgene expression activated by a chemical inducer or an inducer of non-plant origin are desirable tools for both basic plant research…”
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Finite element modeling of lateral pipeline–soil interactions in dense sand
Published in Canadian geotechnical journal (01-03-2016)“…Finite element (FE) analyses of pipeline–soil interaction for pipelines buried in dense sand subjected to lateral ground displacements are presented in this…”
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Experimental Study of Structural Response of Lined-Corrugated HDPE Pipe Subjected to Normal Fault
Published in Journal of geotechnical and geoenvironmental engineering (01-12-2019)“…AbstractBuried lined-corrugated high density polyethylene (HDPE) pipes have been applied to transport sewage for decades. During its service life, a pipe of…”
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Numerical modeling of normal fault-pipeline interaction and comparison with centrifuge tests
Published in Soil dynamics and earthquake engineering (1984) (01-02-2018)“…Pipelines extend thousands of kilometers across wide geographic areas to provide products for modern life. It is inevitable therefore that pipelines must pass…”
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New design equations for corrugated steel culverts responding to live loads
Published in Canadian geotechnical journal (01-01-2024)“…The current design provisions for corrugated steel culverts in North America consider thrust at the springline to be the critical mechanism and location,…”
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Impact of soil erosion voids on reinforced concrete pipe responses to surface loads
Published in Tunnelling and underground space technology (01-12-2018)“…•Erosion voids at the springlines cause pipes to crack at lower loads.•Erosion voids resulted in an overall increase in bending moments especially at…”
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10
Germline Genetic IKZF1 Variation and Predisposition to Childhood Acute Lymphoblastic Leukemia
Published in Cancer cell (14-05-2018)“…Somatic genetic alterations of IKZF1, which encodes the lymphoid transcription factor IKAROS, are common in high-risk B-progenitor acute lymphoblastic leukemia…”
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11
Testing and analysis of PVC liners under simulated grouting pressure
Published in Engineering structures (01-01-2022)“…•Develop a test setup and procedure to undertake buckling experiments.•Investigate the response of PVC liner under two different loading conditions.•Compare…”
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Live-attenuated pediatric parainfluenza vaccine expressing 6P-stabilized SARS-CoV-2 spike protein is protective against SARS-CoV-2 variants in hamsters
Published in PLoS pathogens (01-06-2023)“…The pediatric live-attenuated bovine/human parainfluenza virus type 3 (B/HPIV3)-vectored vaccine expressing the prefusion-stabilized SARS-CoV-2 spike (S)…”
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13
Human norovirus targets enteroendocrine epithelial cells in the small intestine
Published in Nature communications (02-06-2020)“…Human noroviruses are a major cause of diarrheal illness, but pathogenesis is poorly understood. Here, we investigate the cellular tropism of norovirus in…”
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Evaluation and comparison of different detection technologies on simulated voids near buried pipes
Published in Tunnelling and underground space technology (01-05-2022)“…•Assess performance of different technologies for detecting erosion voids near pipes.•Compare void detection results for these technologies.•Give…”
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15
Fatal progression of experimental visceral leishmaniasis is associated with intestinal parasitism and secondary infection by commensal bacteria, and is delayed by antibiotic prophylaxis
Published in PLoS pathogens (01-04-2020)“…Leishmania donovani causes visceral leishmaniasis (VL), which is typically fatal without treatment. There is substantial variation between individuals in rates…”
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Immunity to LuloHya and Lundep, the salivary spreading factors from Lutzomyia longipalpis, protects against Leishmania major infection
Published in PLoS pathogens (03-05-2018)“…Salivary components from disease vectors help arthropods to acquire blood and have been shown to enhance pathogen transmission in different model systems. Here…”
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A nonhuman primate model for genital herpes simplex virus 2 infection that results in vaginal vesicular lesions, virus shedding, and seroconversion
Published in PLoS pathogens (03-09-2024)“…The most commonly used animal models for evaluating the efficacy of HSV-2 candidate vaccines are mice and guinea pigs. While numerous HSV-2 vaccine candidates…”
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A single intranasal dose of a live-attenuated parainfluenza virus-vectored SARS-CoV-2 vaccine is protective in hamsters
Published in Proceedings of the National Academy of Sciences - PNAS (14-12-2021)“…Single-dose vaccines with the ability to restrict SARS-CoV-2 replication in the respiratory tract are needed for all age groups, aiding efforts toward control…”
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Prophylaxis With a Middle East Respiratory Syndrome Coronavirus (MERS-CoV)–Specific Human Monoclonal Antibody Protects Rabbits From MERS-CoV Infection
Published in The Journal of infectious diseases (15-05-2016)“…With >1600 documented human infections with Middle East respiratory syndrome coronavirus (MERS-CoV) and a case fatality rate of approximately 36%, medical…”
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Role of humoral immunity against hepatitis B virus core antigen in the pathogenesis of acute liver failure
Published in Proceedings of the National Academy of Sciences - PNAS (27-11-2018)“…Hepatitis B virus (HBV)-associated acute liver failure (ALF) is a dramatic clinical syndrome leading to death or liver transplantation in 80% of cases. Due to…”
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