Search Results - "Moore, Dianne W."

Developing 3D Organoid Raft Cultures from Patient-Derived Xenografts as Rapid Models to Screen Efficacy of Experimental Therapeutics by Bajpai, Prachi, Banerjee, Nilam Sanjib, Moore, Dianne W, Kim, Hyung-Gyoon, Afaq, Farrukh, Contreras, Carlo M, Heslin, Martin J, Reddy, Vishnu B, Peter, Shajan, Varambally, Sooryanarayana, Al Diffalha, Sameer, Manne, Upender

“…Reliable preclinical models are needed for screening new cancer drugs. Thus, we developed an improved 3D tumor organoid model termed "organoid raft cultures"…”
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Vorinostat, a pan-HDAC inhibitor, abrogates productive HPV-18 DNA amplification by Banerjee, N. Sanjib, Moore, Dianne W., Broker, Thomas R., Chow, Louise T.

“…Human papillomaviruses (HPVs) cause epithelial proliferative diseases. Persistent infection of the mucosal epithelia by the high-risk genotypes can progress to…”
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NVN1000, a novel nitric oxide-releasing compound, inhibits HPV-18 virus production by interfering with E6 and E7 oncoprotein functions by Banerjee, N. Sanjib, Moore, Dianne W., Wang, Hsu-Kun, Broker, Thomas R., Chow, Louise T.

“…•Six daily 1 h topical applications of 2 mg/ml NVN1000, a NO-releasing polymer, abrogated HPV-18 progeny virus production.•NVN1000 inhibits terminal squamous…”
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Abstract LB250: Development of organoid raft cultures of cervical, breast and glioblastoma tumors as quick economical ex vivo human cancer models for pre-clinical drug evaluation by Banerjee, Nilam Sanjib, Moore, Dianne W., Gangrade, Abhisek, Buchsbaum, Donald J., Nabors, Luise Burt, Broker, Thomas R., Chow, Louise T.

“…Background: In the past few years, 3D organoid cultures of patient-derived tumors or patient-derived xenografts have gained significant attention as faster and…”
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Abstract LB249: Development of 3D organoid raft cultures of colon cancer as a model to screen the therapeutic efficacy of PRIMA-1Met (APR-246) by Banerjee, Sanjib Nilam, Bajpai, Prachi, Elkholy, Amr, Moore, Dianne W., Kim, Hyung Gyoon, Agarwal, Sumit, Behring, Michael, Al Diffalha, Sameer, Manne, Upender

“…Background: Cancer is among the leading causes of death worldwide. Hence, new drugs and faster screening models are needed. However, costly experiments for…”
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