Search Results - "Moore, Chad"

Auricular acupuncture for adult tonsillectomy by Shah, Anil N., Moore, Chad B., Brigger, Matthew T.

“…Objectives Adult tonsillectomy causes significant postoperative pain that can last over 14 days, but narcotic regimens only provide a modest reduction in pain…”
Get full text

Opioid-Sparing Anesthesia: Gabapentin and Postoperative Pain by Ladich, Elaine M., Zhou, Kelly Q., Spence, Dennis L., Moore, Chad B.

“…Nonopioid analgesics are commonly used to augment or replace opioids in the perioperative setting. Perianesthesia nurses must consider timing and…”
Get full text

Metabolic pathways of inhaled glucocorticoids by the CYP3A enzymes by Moore, Chad D, Roberts, Jessica K, Orton, Christopher R, Murai, Takahiro, Fidler, Trevor P, Reilly, Christopher A, Ward, Robert M, Yost, Garold S

“…Asthma is one of the most prevalent diseases in the world, for which the mainstay treatment has been inhaled glucocorticoids (GCs). Despite the widespread use…”
Get full text

Training Program for Ultrasound-Guided Intravenous Catheter Insertion by Filipovich, Samantha J, Dilgard, John W, Conrad, Simon P, Moore, Chad B, Hefley, Justin B

“…ABSTRACT Introduction Ultrasound guidance is now widely available in military treatment facilities and civilian hospitals alike, both in the USA and in…”
Get full text

Three-dimensional reconstruction of leukocyte internalisation in the luminal uterine epithelium following mating by Moore, Chad L., Shami, Gerald J., Dowland, Samson N., Lindsay, Laura A., Braet, Filip, Murphy, Christopher R.

“…Following mating, leukocytes are recruited to the uterine epithelium where they phagocytose spermatozoa and mediate maternal immune tolerance as well as a mild…”
Get full text

Mechanisms of the emission of mercury from soil: Role of UV radiation by Moore, Chad, Carpi, Anthony

“…Light has been previously shown to play a role in the emission of mercury from soil; however, the mechanisms involved in this process are not well understood…”
Get full text

Correlated light and electron microscopy observations of the uterine epithelial cell actin cytoskeleton using fluorescently labeled resin-embedded sections by Moore, Chad L., Cheng, Delfine, Shami, Gerald J., Murphy, Christopher R.

“…•A ‘single process’ CLEM protocol that retains fluorescence in resin-embedded ultrathin sections.•Multi-platform imaging with greater accuracy and without…”
Get full text

Perioperative Dexamethasone for Patients With Diabetes and Its Effect on Blood Glucose After Surgery by Bonilla, Jose L., Rodriguez-Torres, Jeanette B., Verar, Gilbert L., Mason-Nguyen, Jill, Moore, Chad B.

“…P Perioperative administration of single-dose dexamethasone helps reduce postoperative nausea and vomiting, inflammation, and pain. However, it is unclear…”
Get full text

Resuming Breastfeeding After Surgery: Influencing Practice Recommendations by Moore, Chad B., Bond, Jeremiah D., Bundoc, Eliseo G., Hefley, Justin B., Wofford, Kenneth A., Bonds, Raymond L.

“…Mothers often request guidance on when it is safe to resume breastfeeding after surgery. At our institution, this guidance was inconsistent and not…”
Get full text

Metabolism of beclomethasone dipropionate by cytochrome P450 3A enzymes by Roberts, Jessica K, Moore, Chad D, Ward, Robert M, Yost, Garold S, Reilly, Christopher A

“…Inhaled glucocorticoids, such as beclomethasone dipropionate (BDP), are the mainstay treatment of asthma. However, ≈ 30% of patients exhibit little to no…”
Get more information

Increasing Access to Auricular Acupuncture for Postoperative Nausea and Vomiting by Moore, Chad B., Hickey, Anita H.

“…Postoperative nausea and vomiting (PONV) affects more than 30% of surgical patients. Auricular acupuncture (AA) has been shown to decrease the incidence of…”
Get full text

Respective roles of CYP2A5 and CYP2F2 in the bioactivation of 3-methylindole in mouse olfactory mucosa and lung: studies using Cyp2a5-null and Cyp2f2-null mouse models by Zhou, Xin, D'Agostino, Jaime, Li, Lei, Moore, Chad D, Yost, Garold S, Ding, Xinxin

“…The aim of this study was to determine whether mouse CYP2A5 and CYP2F2 play critical roles in the bioactivation of 3-methylindole (3MI), a tissue-selective…”
Get full text

Experimental Evaluation of the FluChip Diagnostic Microarray for Influenza Virus Surveillance by Townsend, Michael B, Dawson, Erica D, Mehlmann, Martin, Smagala, James A, Dankbar, Daniela M, Moore, Chad L, Smith, Catherine B, Cox, Nancy J, Kuchta, Robert D, Rowlen, Kathy L

“…Global surveillance of influenza is critical for improvements in disease management and is especially important for early detection, rapid intervention, and a…”
Get full text

MAPK signaling pathways regulate IL-8 mRNA stability and IL-8 protein expression in cystic fibrosis lung epithelial cell lines by Bhattacharyya, Sharmistha, Gutti, Usha, Mercado, Jose, Moore, Chad, Pollard, Harvey B, Biswas, Roopa

“…Cystic fibrosis (CF) is characterized by a massive proinflammatory phenotype in the lung, caused by mutations in the CFTR gene. IL-8 and other proinflammatory…”
Get more information

CYP3A4-Mediated Oxygenation versus Dehydrogenation of Raloxifene by Moore, Chad D, Reilly, Christopher A, Yost, Garold S

“…Raloxifene was approved in 2007 by the FDA for the chemoprevention of breast cancer in postmenopausal women at high risk for invasive breast cancer. Approval…”
Get full text

A Presenilin Dimer at the Core of the γ-Secretase Enzyme: Insights from Parallel Analysis of Notch 1 and APP Proteolysis by Schroeter, Eric H., Ma. Xenia G. Ilagan, Brunkan, Anne L., Hecimovic, Silva, Li, Yue-ming, Xu, Min, Lewis, Huw D., Saxena, Meera T., De Strooper, Bart, Coonrod, Archie, Tomita, Taisuke, Iwatsubo, Takeshi, Moore, Chad L., Goate, Alison, Wolfe, Michael S., Shearman, Mark, Kopan, Raphael

“…Notch receptors and the amyloid precursor protein are type I membrane proteins that are proteolytically cleaved within their transmembrane domains by a…”
Get full text

Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1 by Esler, W P, Kimberly, W T, Ostaszewski, B L, Diehl, T S, Moore, C L, Tsai, J Y, Rahmati, T, Xia, W, Selkoe, D J, Wolfe, M S

“…The beta-amyloid precursor protein (beta-APP), which is involved in the pathogenesis of Alzheimer's disease, and the Notch receptor, which is responsible for…”
Get full text

Improved Cytochrome P450 3A4 Molecular Models Accurately Predict the Phe215 Requirement for Raloxifene Dehydrogenation Selectivity by Moore, Chad D, Shahrokh, Kiumars, Sontum, Stephen F, Cheatham, Thomas E, Yost, Garold S

“…The use of molecular modeling in conjunction with site-directed mutagenesis has been extensively used to study substrate orientation within cytochrome P450…”
Get full text

Identification of A/H5N1 Influenza Viruses Using a Single Gene Diagnostic Microarray by Dawson, Erica D, Moore, Chad L, Dankbar, Daniela M, Mehlmann, Martin, Townsend, Michael B, Smagala, James A, Smith, Catherine B, Cox, Nancy J, Kuchta, Robert D, Rowlen, Kathy L

“…In previous work, a simple diagnostic DNA microarray that targeted only the matrix gene segment of influenza A (MChip) was developed and evaluated with patient…”
Get full text

Peptidomimetic Probes and Molecular Modeling Suggest That Alzheimer's γ-Secretase Is an Intramembrane-Cleaving Aspartyl Protease by Wolfe, Michael S, Xia, Weiming, Moore, Chad L, Leatherwood, Dartha D, Ostaszewski, Beth, Rahmati, Talat, Donkor, Isaac O, Selkoe, Dennis J

“…The amyloid β-protein (Aβ), implicated in the pathogenesis of Alzheimer's disease (AD), is a proteolytic metabolite generated by the sequential action of β-…”
Get full text