Search Results - "Moore, CL"

A Processive Protein Chimera Introduces Mutations across Defined DNA Regions In Vivo by Moore, Christopher L, Papa, Louis J, Shoulders, Matthew D

“…Laboratory time scale evolution in vivo relies on the generation of large, mutationally diverse gene libraries to rapidly explore biomolecule sequence…”
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Prospective multicenter evaluation of the pulmonary embolism rule‐out criteria by KLINE, J. A., COURTNEY, D. M., KABRHEL, C., MOORE, C. L., SMITHLINE, H. A, PLEWA, M. C., RICHMAN, P. B., O'NEIL, B. J., NORDENHOLZ, K.

“…Backgound: Over‐investigation of low‐risk patients with suspected pulmonary embolism (PE) represents a growing problem. The combination of gestalt estimate of…”
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DNA damage induces targeted, genome-wide variation of poly(A) sites in budding yeast by Graber, Joel H, Nazeer, Fathima I, Yeh, Pei-chun, Kuehner, Jason N, Borikar, Sneha, Hoskinson, Derick, Moore, Claire L

“…Systemic response to DNA damage and other stresses is a complex process that includes changes in the regulation and activity of nearly all stages of gene…”
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Ultrasonography in Community Emergency Departments in the United States: Access to Ultrasonography Performed by Consultants and Status of Emergency Physician-Performed Ultrasonography by Moore, Christopher L., Molina, Alex A., Lin, Henry

“…Nearly all emergency medicine residency programs provide some training in emergency physician-performed ultrasonography, but the extent of emergency…”
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Prevention of catheter-related bloodstream infections in patients on hemodialysis: challenges and management strategies by Soi, Vivek, Moore, Carol L, Kumbar, Lalathakasha, Yee, Jerry

“…Catheter-related bloodstream infections are a significant source of morbidity and mortality in the end-stage renal disease population. Although alternative…”
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Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1 by Esler, W P, Kimberly, W T, Ostaszewski, B L, Diehl, T S, Moore, C L, Tsai, J Y, Rahmati, T, Xia, W, Selkoe, D J, Wolfe, M S

“…The beta-amyloid precursor protein (beta-APP), which is involved in the pathogenesis of Alzheimer's disease, and the Notch receptor, which is responsible for…”
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Determination of Left Ventricular Function by Emergency Physician Echocardiography of Hypotensive Patients by Moore, Christopher L., Rose, Geoffrey A., Tayal, Vivek S., Sullivan, D. Matthew, Arrowood, James A., Kline, Jeffrey A.

“…Objective: To determine whether emergency physicians (EPs) with goal‐directed training can use echocardiography to accurately assess left ventricular function…”
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Organization and Function of APT, a Subcomplex of the Yeast Cleavage and Polyadenylation Factor Involved in the Formation of mRNA and Small Nucleolar RNA 3′-Ends by Nedea, Eduard, He, Xiaoyuan, Kim, Minkyu, Pootoolal, Jeff, Zhong, Guoqing, Canadien, Veronica, Hughes, Timothy, Buratowski, Stephen, Moore, Claire L., Greenblatt, Jack

“…Messenger RNA 3′-end formation is functionally coupled to transcription by RNA polymerase II. By tagging and purifying Ref2, a non-essential protein previously…”
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A Presenilin Dimer at the Core of the γ-Secretase Enzyme: Insights from Parallel Analysis of Notch 1 and APP Proteolysis by Schroeter, Eric H., Ma. Xenia G. Ilagan, Brunkan, Anne L., Hecimovic, Silva, Li, Yue-ming, Xu, Min, Lewis, Huw D., Saxena, Meera T., De Strooper, Bart, Coonrod, Archie, Tomita, Taisuke, Iwatsubo, Takeshi, Moore, Chad L., Goate, Alison, Wolfe, Michael S., Shearman, Mark, Kopan, Raphael

“…Notch receptors and the amyloid precursor protein are type I membrane proteins that are proteolytically cleaved within their transmembrane domains by a…”
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Peptidomimetic Probes and Molecular Modeling Suggest That Alzheimer's γ-Secretase Is an Intramembrane-Cleaving Aspartyl Protease by Wolfe, Michael S, Xia, Weiming, Moore, Chad L, Leatherwood, Dartha D, Ostaszewski, Beth, Rahmati, Talat, Donkor, Isaac O, Selkoe, Dennis J

“…The amyloid β-protein (Aβ), implicated in the pathogenesis of Alzheimer's disease (AD), is a proteolytic metabolite generated by the sequential action of β-…”
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Hospitalisation rates and associated factors in community‐based cohorts of HIV‐infected and ‐uninfected gay and bisexual men by Moore, CL, Grulich, AE, Prestage, G, Gidding, HF, Jin, F, Mao, L, Petoumenos, K, Zablotska, IB, Poynten, IM, Law, MG, Amin, J

“…Objectives There is evidence that HIV‐positive patients are suffering from a greater burden of morbidity as they age due to nonAIDS‐related complications. To…”
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Functional interactions between the transcription and mRNA 3' end processing machineries mediated by Ssu72 and Sub1 by He, Xiaoyuan, Khan, Asad U, Cheng, Hailing, Pappas, Jr, Donald L, Hampsey, Michael, Moore, Claire L

“…Transcription and processing of pre-mRNA are coupled events. By using a combination of biochemical, molecular, and genetic methods, we have found that the…”
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MChip:  A Tool for Influenza Surveillance by Dawson, Erica D, Moore, Chad L, Smagala, James A, Dankbar, Daniela M, Mehlmann, Martin, Townsend, Michael B, Smith, Catherine B, Cox, Nancy J, Kuchta, Robert D, Rowlen, Kathy L

“…The design and characterization of a low-density microarray for subtyping influenza A is presented. The microarray consisted of 15 distinct oligonucleotides…”
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γ-Secretase Inhibitors Repress Thymocyte Development by Hadland, Brandon K., Manley, Nancy R., Su, Dong-ming, Longmore, Gregory D., Moore, Chad L., Wolfe, Michael S., Schroeter, Eric H., Kopan, Raphael

“…A major therapeutic target in the search for a cure to the devastating Alzheimer's disease is γ-secretase. This activity resides in a multiprotein enzyme…”
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Performance, Training, Quality Assurance, and Reimbursement of Emergency Physician-Performed Ultrasonography at Academic Medical Centers by Moore, Christopher L, Gregg, Sara, Lambert, Michael

“…Objective. To determine the current state of bedside emergency physician–performed ultrasonography in terms of prevalence, training, quality assurance, and…”
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Rna15 Interaction with the A-Rich Yeast Polyadenylation Signal Is an Essential Step in mRNA 3′-End Formation by Gross, Stefan, Moore, Claire L.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Facile Polymerization of dNTPs Bearing Unnatural Base Analogues by DNA Polymerase α and Klenow Fragment (DNA Polymerase I) by Chiaramonte, Molly, Moore, Chad L, Kincaid, Kristi, Kuchta, Robert D

“…The high fidelity of DNA replication is largely dependent upon accurate incorporation of dNTPs by DNA polymerases. To study the mechanism underlying nucleotide…”
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Utility of Bedside Bladder Ultrasound Before Urethral Catheterization in Young Children by Chen, Lei, Hsiao, Allen L, Moore, Christopher L, Dziura, James D, Santucci, Karen A

“…Urethral catheterization is the method of choice for obtaining samples for urine culture and urine analysis in infants. Before the procedure, there is little…”
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Kin28, the TFIIH-Associated Carboxy-Terminal Domain Kinase, Facilitates the Recruitment of mRNA Processing Machinery to RNA Polymerase II by Rodriguez, Christine R., Cho, Eun-Jung, Keogh, Michael-C., Moore, Claire L., Greenleaf, Arno L., Buratowski, Stephen

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Origin and evolution of a submarine large igneous province: the Kerguelen Plateau and Broken Ridge, southern Indian Ocean by Frey, F.A., Coffin, M.F., Wallace, P.J., Weis, D., Zhao, X., Wise, S.W., Wähnert, V., Teagle, D.A.H., Saccocia, P.J., Reusch, D.N., Pringle, M.S., Nicolaysen, K.E., Neal, C.R., Müller, R.D., Moore, C.L., Mahoney, J.J., Keszthelyi, L., Inokuchi, H., Duncan, R.A., Delius, H., Damuth, J.E., Damasceno, D., Coxall, H.K., Borre, M.K., Boehm, F., Barling, J., Arndt, N.T., Antretter, M.

“…Oceanic plateaus form by mantle processes distinct from those forming oceanic crust at divergent plate boundaries. Eleven drillsites into igneous basement of…”
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