Search Results - "Moore, Bob"

Type 2 cannabinoid receptor expression on microglial cells regulates neuroinflammation during graft-versus-host disease by Moe, Alison, Rayasam, Aditya, Sauber, Garrett, Shah, Ravi K, Doherty, Ashley, Yuan, Cheng-Yin, Szabo, Aniko, Moore, 2nd, Bob M, Colonna, Marco, Cui, Weiguo, Romero, Julian, Zamora, Anthony E, Hillard, Cecilia J, Drobyski, William R

“…Neuroinflammation is a recognized complication of immunotherapeutic approaches such as immune checkpoint inhibitor treatment, chimeric antigen receptor…”
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Synthesis and biological evaluation of a ring analogs of the selective CB2 inverse agonist SMM-189 by Alghamdi, Sahar S., Mustafa, Suni M., Moore II, Bob M.

“…[Display omitted] Microglia are the principle cell type driving sustained neuroinflammation in neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and…”
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Inverse Agonism of Cannabinoid Receptor Type 2 Confers Anti-inflammatory and Neuroprotective Effects Following Status Epileptics by Yu, Ying, Li, Lexiao, Nguyen, Davis T., Mustafa, Suni M., Moore, Bob M., Jiang, Jianxiong

“…Prolonged status epilepticus (SE) in humans causes high mortality and brain inflammation–associated neuronal injury and morbidity in survivors. Currently, the…”
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Selective Cannabinoid 2 Receptor Stimulation Reduces Tubular Epithelial Cell Damage after Renal Ischemia-Reperfusion Injury by Pressly, Jeffrey D, Mustafa, Suni M, Adibi, Ammaar H, Alghamdi, Sahar, Pandey, Pankaj, Roy, Kuldeep K, Doerksen, Robert J, Moore, Jr, Bob M, Park, Frank

“…Ischemia-reperfusion injury (IRI) is a common cause of acute kidney injury (AKI), which is an increasing problem in the clinic and has been associated with…”
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Motor, visual and emotional deficits in mice after closed-head mild traumatic brain injury are alleviated by the novel CB2 inverse agonist SMM-189 by Reiner, Anton, Heldt, Scott A, Presley, Chaela S, Guley, Natalie H, Elberger, Andrea J, Deng, Yunping, D'Surney, Lauren, Rogers, Joshua T, Ferrell, Jessica, Bu, Wei, Del Mar, Nobel, Honig, Marcia G, Gurley, Steven N, Moore, 2nd, Bob M

“…We have developed a focal blast model of closed-head mild traumatic brain injury (TBI) in mice. As true for individuals that have experienced mild TBI, mice…”
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Anti-inflammatory activity of cannabinoid receptor 2 ligands in primary hPDL fibroblasts by Abidi, Ammaar H., Presley, Chaela S., Dabbous, Mustafa, Tipton, David A., Mustafa, Suni M., Moore, Bob M.

“…•Characterization of IL-6 and MCP-1 expression in primary human PDL fibroblasts.•IL-6 and MCP-1 response in the presence and absence of stimuli.•CB2 ligands…”
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Piet de Rooy, A Tiny Spot on the Earth: The Political Culture of the Netherlands in the Nineteenth and Twentieth Century by Moore, Bob

“…Piet de Rooy, A Tiny Spot on the Earth: The Political Culture of the Netherlands in the Nineteenth and Twentieth Century (Amsterdam: Amsterdam University…”
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Amelioration of visual deficits and visual system pathology after mild TBI with the cannabinoid type-2 receptor inverse agonist SMM-189 by Guley, Natalie M., Del Mar, Nobel A., Ragsdale, Tyler, Li, Chunyan, Perry, Aaron M., Moore, Bob M., Honig, Marcia G., Reiner, Anton

“…Mild TBI is often accompanied by visual system dysfunction and injury, which is at least partly caused by microglial neuroinflammatory processes initiated by…”
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Cannabinoid type‐2 receptor agonist, inverse agonist, and anandamide regulation of inflammatory responses in IL‐1β stimulated primary human periodontal ligament fibroblasts by Abidi, Ammaar H., Alghamdi, Sahar S., Dabbous, Mustafa Kh, Tipton, David A., Mustafa, Suni M., Moore, Bob M.

“…Objective The aim of this study is to understand the role of cannabinoid type 2 receptor (CB2R) during periodontal inflammation and to identify…”
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Marieke Meeuwenoord, Het hele leven is hier een wereld op zichzelf. De geschiedenis van Kamp Vught; Eva Moraal, Als ik morgen niet op transport ga…. Kamp Westerbork in beleving en herinneringen by Moore, Bob

“…Marieke Meeuwenoord, Het hele leven is hier een wereld op zichzelf. De geschiedenis van Kamp Vught (Dissertatie Universiteit van Amsterdam 2011; Amsterdam: De…”
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Mild Traumatic Brain Injury Produces Neuron Loss That Can Be Rescued by Modulating Microglial Activation Using a CB2 Receptor Inverse Agonist by Bu, Wei, Ren, Huiling, Deng, Yunping, Del Mar, Nobel, Guley, Natalie M, Moore, Bob M, Honig, Marcia G, Reiner, Anton

“…We have previously reported that mild TBI created by focal left-side cranial blast in mice produces widespread axonal injury, microglial activation, and a…”
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Cannabinoid Type 2 Receptor Activation Reduces the Progression of Kidney Fibrosis Using a Mouse Model of Unilateral Ureteral Obstruction by Swanson, Mallory L, Regner, Kevin R, Moore, 2nd, Bob M, Park, Frank

“…Kidney fibrosis is a hallmark consequence of all forms of chronic kidney disease with few available treatment modalities. In this study, we performed the…”
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Cannabinoid Receptor 2 (CB2) Inverse Agonist SMM-189 Induces Expression of Endogenous CB2 and Protein Kinase A That Differentially Modulates the Immune Response and Suppresses Experimental Colitis by Kiran, Sonia, Rakib, Ahmed, Moore, Bob M, Singh, Udai P

“…The causes of Crohn's disease (CD) and ulcerative colitis (UC), the two most common forms of inflammatory bowel disease (IBD), are multi-factorial and include…”
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Amelioration of visual deficits and visual system pathology after mild TBI via the cannabinoid Type-2 receptor inverse agonism of raloxifene by Honig, Marcia G., Del Mar, Nobel A., Henderson, Desmond L., Ragsdale, Tyler D., Doty, John B., Driver, Jake H., Li, Chunyan, Fortugno, Andrew P., Mitchell, William M., Perry, Aaron M., Moore, Bob M., Reiner, Anton

“…Visual deficits after traumatic brain injury (TBI) are common, but interventions that limit the post-trauma impairments have not been identified. We have found…”
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Cannabinoid receptor 1 ligands revisited: Pharmacological assessment in the ACTOne system by Presley, Chaela S., Abidi, Ammaar H., Moore, Bob M.

“…In vitro cannabinoid pharmacology has evolved over time from simple receptor binding to include [35S]GTPγ, β-arrestin, and cAMP assays. Each assay has benefits…”
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Raloxifene Modulates Microglia and Rescues Visual Deficits and Pathology After Impact Traumatic Brain Injury by Honig, Marcia G., Del Mar, Nobel A., Henderson, Desmond L., O’Neal, Dylan, Doty, John B., Cox, Rachel, Li, Chunyan, Perry, Aaron M., Moore, Bob M., Reiner, Anton

“…Mild traumatic brain injury (TBI) involves widespread axonal injury and activation of microglia, which initiates secondary processes that worsen the TBI…”
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Synthesis and biological evaluation of (3′,5′-dichloro-2,6-dihydroxy-biphenyl-4-yl)-aryl/alkyl-methanone selective CB2 inverse agonist by Presley, Chaela S., Mustafa, Suni M., Abidi, Ammaar H., Moore, Bob M.

“…[Display omitted] Cannabinoid receptor 2 (CB2) selective agonists and inverse agonists possess significant potential as therapeutic agents for regulating…”
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Raloxifene, a cannabinoid type-2 receptor inverse agonist, mitigates visual deficits and pathology and modulates microglia after ocular blast by Honig, Marcia G., Del Mar, Nobel A., Henderson, Desmond L., O'Neal, Dylan, Yammanur, Meghna, Cox, Rachel, Li, Chunyan, Perry, Aaron M., Moore, Bob M., Reiner, Anton

“…Visual deficits after ocular blast injury (OBI) are common, but pharmacological approaches to improve long-term outcomes have not been identified. Blast forces…”
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DNA damage is overcome by TRIP13 overexpression during cisplatin nephrotoxicity by Hama, Taketsugu, Nagesh, Prashanth Kb, Chowdhury, Pallabita, Moore, 2nd, Bob M, Yallapu, Murali M, Regner, Kevin R, Park, Frank

“…Cisplatin is a commonly used chemotherapeutic agent to treat a wide array of cancers that is frequently associated with toxic injury to the kidney due to…”
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Corrigendum to ‘Cannabinoid receptor 1 ligands revisited: Pharmacological assessment in the ACTOne system’ [Analytical Biochemistry 498 (2016) 8–28] by Presley, Chaela S., Abidi, Ammaar H., Moore, Bob M.

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