Search Results - "Moore, Anthony N."

A method for assessing tissue respiration in anatomically defined brain regions by Underwood, Erica, Redell, John B., Zhao, Jing, Moore, Anthony N., Dash, Pramod K.

“…The survival and function of brain cells requires uninterrupted ATP synthesis. Different brain structures subserve distinct neurological functions, and…”
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Endoplasmic Reticulum Stress Contributes to the Loss of Newborn Hippocampal Neurons after Traumatic Brain Injury by Hood, Kimberly N, Zhao, Jing, Redell, John B, Hylin, Michael J, Harris, Brynn, Perez, Alec, Moore, Anthony N, Dash, Pramod K

“…Adult hippocampal neurogenesis has been shown to be required for certain types of cognitive function. For example, studies have shown that these neurons are…”
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Valproate administered after traumatic brain injury provides neuroprotection and improves cognitive function in rats by Dash, Pramod K, Orsi, Sara A, Zhang, Min, Grill, Raymond J, Pati, Shibani, Zhao, Jing, Moore, Anthony N

“…Traumatic brain injury (TBI) initiates a complex series of neurochemical and signaling changes that lead to pathological events including neuronal…”
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Biomarkers for the diagnosis and prognosis of mild traumatic brain injury/concussion by Jeter, Cameron B, Hergenroeder, Georgene W, Hylin, Michael J, Redell, John B, Moore, Anthony N, Dash, Pramod K

“…Mild traumatic brain injury (mTBI) results from a transfer of mechanical energy into the brain from traumatic events such as rapid acceleration/deceleration, a…”
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Activation of Alpha 7 Cholinergic Nicotinic Receptors Reduce Blood-Brain Barrier Permeability following Experimental Traumatic Brain Injury by Dash, Pramod K, Zhao, Jing, Kobori, Nobuhide, Redell, John B, Hylin, Michael J, Hood, Kimberly N, Moore, Anthony N

“…Traumatic brain injury (TBI) is a major human health concern that has the greatest impact on young men and women. The breakdown of the blood-brain barrier…”
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Disruption of the Perineuronal Net in the Hippocampus or Medial Prefrontal Cortex Impairs Fear Conditioning by Hylin, Michael J, Orsi, Sara A, Moore, Anthony N, Dash, Pramod K

“…The perineuronal net (PNN) surrounds neurons in the central nervous system and is thought to regulate developmental plasticity. A few studies have shown an…”
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Altered Mitochondrial Dynamics and TBI Pathophysiology by Fischer, Tara D, Hylin, Michael J, Zhao, Jing, Moore, Anthony N, Waxham, M Neal, Dash, Pramod K

“…Mitochondrial function is intimately linked to cellular survival, growth, and death. Mitochondria not only generate ATP from oxidative phosphorylation, but…”
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Caudal DMN neurons innervate the spleen and release CART peptide to regulate neuroimmune function by Kobori, Nobuhide, Moore, Anthony N, Redell, John B, Dash, Pramod K

“…Inflammation is a fundamental biological response to injury and infection, which if unregulated can contribute to the pathophysiology of many diseases. The…”
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Enhancing Expression of Nrf2-Driven Genes Protects the Blood Brain Barrier after Brain Injury by Zhao, Jing, Moore, Anthony N, Redell, John B, Dash, Pramod K

“…The integrity of the blood-brain barrier (BBB) is critical for normal brain function, and its compromise contributes to the pathophysiology of a number of CNS…”
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A role for autophagy in long‐term spatial memory formation in male rodents by Hylin, Michael J., Zhao, Jing, Tangavelou, Karthikeyan, Rozas, Natalia S., Hood, Kimberly N., MacGowan, Jacalyn S., Moore, Anthony N., Dash, Pramod K.

“…A hallmark of long‐term memory formation is the requirement for protein synthesis. Administration of protein synthesis inhibitors impairs long‐term memory…”
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Enhanced presynaptic mitochondrial energy production is required for memory formation by Underwood, Erica L., Redell, John B., Hood, Kimberly N., Maynard, Mark E., Hylin, Michael, Waxham, M. Neal, Zhao, Jing, Moore, Anthony N., Dash, Pramod K.

“…Some of the prominent features of long-term memory formation include protein synthesis, gene expression, enhanced neurotransmitter release, increased…”
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Spatial Memory Formation and Memory-Enhancing Effect of Glucose Involves Activation of the Tuberous Sclerosis Complex-Mammalian Target of Rapamycin Pathway by Dash, Pramod K, Orsi, Sara A, Moore, Anthony N

“…The tuberous sclerosis complex-mammalian target of rapamycin (TSC-mTOR) cascade integrates growth factor and nutritional signals to regulate the synthesis of…”
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Involvement of the glycogen synthase kinase-3 signaling pathway in TBI pathology and neurocognitive outcome by Dash, Pramod K, Johnson, Daniel, Clark, Jordan, Orsi, Sara A, Zhang, Min, Zhao, Jing, Grill, Raymond J, Moore, Anthony N, Pati, Shibani

“…Traumatic brain injury (TBI) sets in motion cascades of biochemical changes that result in delayed cell death and altered neuronal architecture. Studies have…”
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Traumatic Brain Injury Alters Methionine Metabolism: Implications for Pathophysiology by Dash, Pramod K, Hergenroeder, Georgene W, Jeter, Cameron B, Choi, H Alex, Kobori, Nobuhide, Moore, Anthony N

“…Methionine is an essential proteinogenic amino acid that is obtained from the diet. In addition to its requirement for protein biosynthesis, methionine is…”
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Analysis of functional pathways altered after mild traumatic brain injury by Redell, John B, Moore, Anthony N, Grill, Raymond J, Johnson, Daniel, Zhao, Jing, Liu, Yin, Dash, Pramod K

“…Concussive injury (or mild traumatic brain injury; mTBI) can exhibit features of focal or diffuse injury patterns. We compared and contrasted the cellular and…”
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Caffeic Acid phenethyl ester protects blood-brain barrier integrity and reduces contusion volume in rodent models of traumatic brain injury by Zhao, Jing, Pati, Shibani, Redell, John B, Zhang, Min, Moore, Anthony N, Dash, Pramod K

“…A number of studies have established a deleterious role for inflammatory molecules and reactive oxygen species (ROS) in the pathology of traumatic brain injury…”
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Serum IL-6: a candidate biomarker for intracranial pressure elevation following isolated traumatic brain injury by Hergenroeder, Georgene W, Moore, Anthony N, McCoy, Jr, J Philip, Samsel, Leigh, Ward, 3rd, Norman H, Clifton, Guy L, Dash, Pramod K

“…Increased intracranial pressure (ICP) is a serious, life-threatening, secondary event following traumatic brain injury (TBI). In many cases, ICP rises in a…”
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Molecular activity underlying working memory by DASH, Pramod K, MOORE, Anthony N, KOBORI, Nobuhide, RUNYAN, Jason D

“…The prefrontal cortex is necessary for directing thought and planning action. Working memory, the active, transient maintenance of information in mind for…”
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A Role for Prefrontal Cortex in Memory Storage for Trace Fear Conditioning by Runyan, Jason D, Moore, Anthony N, Dash, Pramod K

“…The prefrontal cortex has been shown to participate in the association of events separated by time. However, it is not known whether the prefrontal cortex…”
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Identification of serum biomarkers in brain-injured adults: potential for predicting elevated intracranial pressure by Hergenroeder, Georgene, Redell, John B, Moore, Anthony N, Dubinsky, William P, Funk, Robert T, Crommett, John, Clifton, Guy L, Levine, Robert, Valadka, Alex, Dash, Pramod K

“…Brain injury biomarkers may have clinical utility in stratifying injury severity level, predicting adverse secondary events or outcomes, and monitoring the…”
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