Search Results - "Moore, Alison J"
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Mineralization and Bone Resorption Are Regulated by the Androgen Receptor in Male Mice
Published in Journal of bone and mineral research (01-04-2009)“…Androgens play a key role in skeletal growth and bone maintenance; however, their mechanism of action remains unclear. To address this, we selectively deleted…”
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Calcitonin Receptor Plays a Physiological Role to Protect Against Hypercalcemia in Mice
Published in Journal of bone and mineral research (01-08-2008)“…It is well established that calcitonin is a potent inhibitor of bone resorption; however, a physiological role for calcitonin acting through its cognate…”
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3
DNA-binding-dependent androgen receptor signaling contributes to gender differences and has physiological actions in males and females
Published in Journal of endocrinology (01-07-2010)“…We used our genomic androgen receptor (AR) knockout (ARKO) mouse model, in which the AR is unable to bind DNA to: 1) document gender differences between males…”
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4
Discordant effects of vitamin D deficiency in trabecular and cortical bone architecture and strength in growing rodents
Published in Journal of steroid biochemistry and molecular biology (01-07-2010)“…We have previously shown that vitamin D deficiency in young male rats results in significant reduction in femoral trabecular bone volume (BV/TV). However, the…”
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Promoting a culture of openness: Institutional open access policy development and review at a Canadian university
Published in Partnership (2021)“…Institutional open access (OA) policies can act as a solid foundation on which to build university-wide support for open access. This is the first paper to…”
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Promoting a culture of openness: Institutional open access policy development and evaluation at a Canadian university
Published in Partnership (09-12-2021)“…Institutional open access (OA) policies can act as a solid foundation on which to build university-wide support for open access. This is the first paper to…”
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7
Vitamin D Depletion Induces RANKL‐Mediated Osteoclastogenesis and Bone Loss in a Rodent Model
Published in Journal of bone and mineral research (01-11-2008)“…The association between increased risk of hip fracture and low vitamin D status has long been recognized. However, the level of vitamin D required to maintain…”
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Adequate dietary vitamin D and calcium are both required to reduce bone turnover and increased bone mineral volume
Published in The Journal of steroid biochemistry and molecular biology (01-10-2014)“…•25-Hydroxyvitamin D levels are positively associated with bone mineral volume.•Sufficient dietary calcium is required to optimise bone volume.•Lowest bone…”
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The role of the calcitonin receptor in protecting against induced hypercalcemia is mediated via its actions in osteoclasts to inhibit bone resorption
Published in Bone (New York, N.Y.) (01-02-2011)“…Abstract Despite the therapeutic value of calcitonin in treating bone disease, a biological role of endogenous calcitonin is controversial. Having previously…”
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Chronic Daily Headaches in Pediatric Neurology Practice
Published in Journal of child neurology (01-12-2004)“…Using a comprehensive computerized database for a single general pediatric neurology ambulatory practice, the clinical profile, together with the precipitating…”
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Neurodevelopmental outcome of young pediatric intensive care survivors of serious brain injury
Published in Pediatric critical care medicine (01-10-2002)“…To determine the number of children with severe brain injury due to closed head injury or hypoxic-ischemic encephalopathy as a proportion of all admissions of…”
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Course Journals: Leveraging Library Publishing to Engage Students at the Intersection of Open Pedagogy, Scholarly Communications, and Information Literacy
Published in Partnership (14-11-2019)“…This article presents a case study for developing course journals, an approach to student writing and publishing that involves students in the production of an…”
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13
Departing is such sweet sorrow
Published in Cell death and differentiation (01-04-1998)Get full text
Journal Article Conference Proceeding -
14
Antimicrobial activity of cecropins
Published in Journal of antimicrobial chemotherapy (01-06-1996)“…The lytic peptides, cecropins, were originally isolated from the haemolymph of the giant silk moth, Hyalophora cecropia and possess antibacterial and…”
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Extraction of the synthetic lytic peptide, cecropin B, from biological fluid and analysis using reversed-phase high-performance liquid chromatography
Published in Journal of chromatography. Biomedical applications (20-10-1995)“…The lytic peptide cecropin B, originally isolated from the giant silk moth Hyalophora cecropia, has been found to possess antibacterial and cell lysis…”
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Enzyme replacement therapy in a feline model of Maroteaux-Lamy syndrome
Published in The Journal of clinical investigation (15-04-1996)“…We report studies that suggest enzyme replacement therapy will result in a significant reduction in disease progression and tissue pathology in patients with…”
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