Search Results - "Moorani, Khemchand N."

Clinicopathological profile of pediatric renal biopsies at a tertiary care hospital, Pakistan by Sadaf, Asim, Khemchand, Moorani N., Fouzia, Lateef, Asia, Zubair

“…Renal biopsy is an important tool for the diagnosis of acute and chronic glomerular diseases in children. We aimed to analyze the spectrum of clinical…”
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Rapidly progressive glomerulonephritis in children by Moorani, Khemchand N, Aziz, Madiha, Amanullah, Farhana

“…Rapidly progressive glomerulonephritis (RPGN), characterized by a rapid development of nephritis with loss of kidney function in days or weeks, is typically…”
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Defects in the IFT-B Component IFT172 Cause Jeune and Mainzer-Saldino Syndromes in Humans by Halbritter, Jan, Bizet, Albane A., Schmidts, Miriam, Porath, Jonathan D., Braun, Daniela A., Gee, Heon Yung, McInerney-Leo, Aideen M., Krug, Pauline, Filhol, Emilie, Davis, Erica E., Airik, Rannar, Czarnecki, Peter G., Lehman, Anna M., Trnka, Peter, Nitschké, Patrick, Bole-Feysot, Christine, Schueler, Markus, Knebelmann, Bertrand, Burtey, Stéphane, Szabó, Attila J., Tory, Kálmán, Leo, Paul J., Gardiner, Brooke, McKenzie, Fiona A., Zankl, Andreas, Brown, Matthew A., Hartley, Jane L., Maher, Eamonn R., Li, Chunmei, Leroux, Michel R., Scambler, Peter J., Zhan, Shing H., Jones, Steven J., Kayserili, Hülya, Tuysuz, Beyhan, Moorani, Khemchand N., Constantinescu, Alexandru, Krantz, Ian D., Kaplan, Bernard S., Shah, Jagesh V., Hurd, Toby W., Doherty, Dan, Katsanis, Nicholas, Duncan, Emma L., Otto, Edgar A., Beales, Philip L., Mitchison, Hannah M., Saunier, Sophie, Hildebrandt, Friedhelm

“…Intraflagellar transport (IFT) depends on two evolutionarily conserved modules, subcomplexes A (IFT-A) and B (IFT-B), to drive ciliary assembly and…”
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Whole exome sequencing identifies causative mutations in the majority of consanguineous or familial cases with childhood-onset increased renal echogenicity by Braun, Daniela A, Schueler, Markus, Halbritter, Jan, Gee, Heon Yung, Porath, Jonathan D, Lawson, Jennifer A, Airik, Rannar, Shril, Shirlee, Allen, Susan J, Stein, Deborah, Al Kindy, Adila, Beck, Bodo B, Cengiz, Nurcan, Moorani, Khemchand N, Ozaltin, Fatih, Hashmi, Seema, Sayer, John A, Bockenhauer, Detlef, Soliman, Neveen A, Otto, Edgar A, Lifton, Richard P, Hildebrandt, Friedhelm

“…Chronically increased echogenicity on renal ultrasound is a sensitive early finding of chronic kidney disease that can be detected before manifestation of…”
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Tumor lysis syndrome in pediatric acute lymphoblastic leukemia at tertiary care center by Naeem, Bilqis, Moorani, Khemchand N, Anjum, Misbah, Imam, Uzma

“…Tumor lysis syndrome (TLS) is common complication of acute lymphoblastic leukemia (ALL). It is characterized by presence of two or more of hyperkalemia,…”
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Etiology, Clinical Profile, and Short-Term Outcome of Children With Acute Kidney Injury by Bai, Shabeeta, Moorani, Khemchand N, Naeem, Bilquis, Ashfaq, Muhammad, Rajesh, Rehman, Ejaz Ur

“…Acute kidney injury (AKI) is a common clinical syndrome in hospitalized children and it imposes heavy burden of mortality and morbidity. In resource-constraint…”
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Vitamin D status in under five children in diverse communities of Karachi by Moorani, Khemchand N, Mustufa, Muhammad Ayaz, Hasan, Syed Furqan, Kubar, Naseem

“…Vitamin D deficiency (VDD) prevalence is very high in pediatric population in developing countries including Pakistan. VDD contribute significantly to…”
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Efficacy of Levamisole in children with Frequent Relapsing and Steroid Dependent Nephrotic Syndrome at Tertiary Care Center-Karachi by Moorani, Khemchand N, Zubair, Aasia Mohammad, Veerwani, Nanga Ram, Hotchandani, Harnam Jaichand

“…To determine the effectiveness of levamisole in maintaining remission of proteinuria in children with frequent relapsing and steroid dependent nephrotic…”
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Nineteen novel NPHS1 mutations in a worldwide cohort of patients with congenital nephrotic syndrome (CNS) by Schoeb, Dominik S., Chernin, Gil, Heeringa, Saskia F., Matejas, Verena, Held, Susanne, Vega-Warner, Virginia, Bockenhauer, Detlef, Vlangos, Christopher N., Moorani, Khemchand N., Neuhaus, Thomas J., Kari, Jameela A., MacDonald, James, Saisawat, Pawaree, Ashraf, Shazia, Ovunc, Bugsu, Zenker, Martin, Hildebrandt, Friedhelm

“…Background. Recessive mutations in the NPHS1 gene encoding nephrin account for ∼40% of infants with congenital nephrotic syndrome (CNS). CNS is defined as…”
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Infantile Spasms: Clinical profile and treatment outcomes by Kulsoom, Shazia, Ibrahim, Shahnaz H, Jafri, Sidra Kaleem, Moorani, Khemchand N, Anjum, Misbah

“…Infantile spasm (IS) is one of the severe epileptic encephalopathies which affect children in early two years of life. Our objective was to determine the…”
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Functional and structural abnormalities of the kidney and urinary tract in severely malnourished children - A hospital based study by Anjum, Misbah, Moorani, Khemchand N, Sameen, Ifra, Mustufa, Muhammad Ayaz, Kulsoom, Shazia

“…The association of malnutrition and systemic diseases like chronic kidney disease (CKD) is well known. Various urinary tract abnormalities may be associated…”
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Comparison of three formulae for estimation of glomerular filtration rate in severely malnourished children at tertiary care facility by Anjum, Misbah, Moorani, Khemchand N, Naeem, Bilquis, Kulsoom, Shazia, Memon, Ashfaq Ahmed

“…First objective was to compare eGFR by Updated Schwartz (US) and Simple Height Independent (SHID) formula with Original Schwartz (OS) in children with Severe…”
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Safety and Adequacy of Ultrasound-Guided Percutaneous Renal Biopsy in Children: A Single-Center Experience by Bux, Kausar Illahi, Moorani, Khemchand N, Qureshi, Hina, Kumari, Usha, Khan, Faheemullah, Farooq, Faryal, Abbas, Fakhar, Aman, Muhammad, Sahito, Abdul Moiz, Musharraff, Faisal, Alam, Muhammad Sami

“…Background Ultrasound-guided percutaneous renal biopsy (PCRB) is a commonly used technique to obtain renal tissue for histopathological diagnosis in children…”
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Frequency of Stillbirths in a Tertiary Care Hospital, Karachi by Mustufa, Muhammad Ayaz, Kulsoom, Shazia, Sameen, Ifra, Moorani, Khemchand N, Memon, Ashfaqe Ahmed, Korejo, Razia

“…Pakistan accounts for the highest stillbirth rate in the world. Therefore, this observational study was planned to determine the prevalence of stillbirths and…”
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Zinc supplement in reduction of relapses in children with steroid sensitive nephrotic syndrome by Sherali, Afroze Ramzan, Moorani, Khemchand N, Chishty, Saeed Hassan, Khan, Shuja Iqbal

“…To determine whether Zinc supplementation could reduce relapse rate in children with nephrotic syndrome. Randomized-controlled trial. National Institute of…”
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Parenteral iron sucrose in iron deficiency anaemia of paediatric chronic kidney disease by Moorani, Khemchand N, Asim, Sadaf

“…Erythropoietin (Epo) and iron therapy plays a major role in the management of renal anaemia. Iron sucrose (IS) has been used to treat iron deficiency anaemia…”
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Infections in children with nephrotic syndrome by Moorani, Khemchand N, Khan, Khalid Mahmood Ahmed, Ramzan, Afroze

“…To determine the different types of infections in nephrotic children and their association with the activity of disease. A descriptive study. It was carried…”
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Aspergillus terreus Peritonitis in a Child on Continuous Ambulatory Peritoneal Dialysis: A Case Report from Pakistan by Moin, Safia, Moorani, Khemchand N., Qureshi, Hina

“…Background: Aspergillus peritonitis is a rare, potentially fatal complication of continuous ambulatory peritoneal dialysis (CAPD). Several cases of fungal…”
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Factors associated with early relapses in children with steroid-sensitive nephrotic syndrome by Serat Jehan, Mohsina Noor Ibrahim, Khemchand N Moorani, Bilquis Abro, Bakhtawar Chandio, Mehwish Riaz

“…Objective: To determine different risk factors associated with relapse in children with steroid-sensitive nephrotic syndrome. Study Design: Cross-sectional…”
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Frequency of urinary metabolic abnormalities in children with renal stone disease by Serat Jehan, Mohsina Noor Ibrahim, Shariq Anis Khan, Bilquis Abro, Khemchand N Moorani, Mehwish Riaz

“…Objective: The key to preventing morbidity and long-term renal problems is thorough metabolic examination of every child with renal stones. This is meant to…”
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