Search Results - "Moons, David"

US elastography-derived shear wave velocity helps distinguish acutely inflamed from fibrotic bowel in a Crohn disease animal model by Dillman, Jonathan R, Stidham, Ryan W, Higgins, Peter D R, Moons, David S, Johnson, Laura A, Rubin, Jonathan M

“…To determine if acoustic radiation force impulse elastography-derived bowel wall shear wave velocity (SWV) allows distinction of acutely inflamed from fibrotic…”
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Ultrasound Elasticity Imaging for Detecting Intestinal Fibrosis and Inflammation in Rats and Humans With Crohn's Disease by Stidham, Ryan W, Xu, Jingping, Johnson, Laura A, Kim, Kang, Moons, David S, McKenna, Barbara J, Rubin, Jonathan M, Higgins, Peter D.R

“…Background Intestinal fibrosis causes many complications of Crohn's disease (CD). Available biomarkers and imaging modalities lack sufficient accuracy to…”
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Intestinal fibrosis is reduced by early elimination of inflammation in a mouse model of IBD: Impact of a “Top‐Down” approach to intestinal fibrosis in mice by Johnson, Laura A., Luke, Amy, Sauder, Kay, Moons, David S., Horowitz, Jeffrey C., Higgins, Peter D.R.

“…Background: The natural history of Crohn's disease follows a path of progression from an inflammatory to a fibrostenosing disease, with most patients requiring…”
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Comparison of noncontrast MRI magnetization transfer and T2-Weighted signal intensity ratios for detection of bowel wall fibrosis in a Crohn's disease animal model by Dillman, Jonathan R., Swanson, Scott D., Johnson, Laura A., Moons, David S., Adler, Jeremy, Stidham, Ryan W., Higgins, Peter D.R.

“…Purpose To compare the abilities of magnetization transfer magnetic resonance imaging (MT‐MRI) and T2‐weighted signal intensity (T2WSI) ratios to detect…”
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Ultrasound Shear Wave Elastography Helps Discriminate Low‐grade From High‐grade Bowel Wall Fibrosis in Ex Vivo Human Intestinal Specimens by Dillman, Jonathan R., Stidham, Ryan W., Higgins, Peter D. R., Moons, David S., Johnson, Laura A., Keshavarzi, Nahid R., Rubin, Jonathan M.

“…Objectives To determine whether bowel wall fibrosis can be detected in freshly resected human intestinal specimens based on ultrasound‐derived shear wave…”
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The Hypoxia-Inducible Factor–C/EBPα Axis Controls Ethanol-Mediated Hepcidin Repression by Anderson, Erik R., Taylor, Matthew, Xue, Xiang, Martin, Angelical, Moons, David S., Omary, M. Bishr, Shah, Yatrik M.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Use of Second Harmonic Generation (SHG) and 2-Photon Emission Imaging to Quantify and Describe the Structure of Tissue Fibrosis in the Rat TNBS Intestinal Fibrosis Model by Johnson, Laura, Moons, David S, Chen, Li, Petitjean, Mathieu, Higgins, Peter D, Stidham, Ryan W

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Characterizing intestinal inflammation and fibrosis in Crohn's disease by photoacoustic imaging: feasibility study by Lei, Hao, Johnson, Laura A, Liu, Shengchun, Moons, David S, Ma, Teng, Zhou, Qifa, Rice, Michael D, Ni, Jun, Wang, Xueding, Higgins, Peter D R, Xu, Guan

“…The pathology of Crohn's disease (CD) is characterized by obstructing intestinal strictures because of inflammation (with high levels of hemoglobin), fibrosis…”
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Can Contrast‐Enhanced Sonography Detect Bowel Wall Fibrosis in Mixed Inflammatory and Fibrotic Crohn Disease Lesions in an Animal Model? by Dillman, Jonathan R., Rubin, Jonathan M., Johnson, Laura A., Moons, David S., Higgins, Peter D. R.

“…Objectives To determine whether contrast‐enhanced sonographic quantitative perfusion parameters can detect bowel wall fibrosis in the setting of mixed…”
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Optimisation of Intestinal Fibrosis and Survival in the Mouse S. Typhimurium Model for Anti-fibrotic Drug Discovery and Preclinical Applications by Johnson, Laura A., Rodansky, Eva S., Moons, David S., Larsen, Scott D., Neubig, Richard R., Higgins, Peter D. R.

“…Abstract Background and Aims: Intestinal fibrosis is a frequent complication in Crohn’s disease [CD]. The mouse Salmonella typhimurium model, due to its…”
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CD73 (ecto‐5′‐nucleotidase) hepatocyte levels differ across mouse strains and contribute to mallory‐denk body formation by Snider, Natasha T., Griggs, Nicholas W., Singla, Amika, Moons, David S., Weerasinghe, Sujith V.W., Lok, Anna S., Ruan, Chunhai, Burant, Charles F., Conjeevaram, Hari S., Omary, M. Bishr

“…Formation of hepatocyte Mallory‐Denk bodies (MDBs), which are aggregates of keratins 8 and 18 (K8/K18), ubiquitin, and the ubiquitin‐binding protein, p62, has…”
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Oxidative stress, Nrf2 and keratin up-regulation associate with Mallory-Denk body formation in mouse erythropoietic protoporphyria by Singla, Amika, Moons, David S., Snider, Natasha T., Wagenmaker, Elizabeth R., Jayasundera, V. Bernadene, Omary, M. Bishr

“…Mallory‐Denk bodies (MDBs) are hepatocyte inclusions commonly seen in steatohepatitis. They are induced in mice by feeding…”
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Fibrinogen‐γ proteolysis and solubility dynamics during apoptotic mouse liver injury: Heparin prevents and treats liver damage by Weerasinghe, Sujith V. W., Moons, David S., Altshuler, Peter J., Shah, Yatrik M., Omary, M. Bishr

“…Fas ligand (FasL)‐mediated hepatocyte apoptosis occurs in the context of acute liver injury that can be accompanied by intravascular coagulation (IC). We…”
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Pituitary Hypoplasia and Lactotroph Dysfunction in Mice Deficient for Cyclin-Dependent Kinase-4 by Moons, David S, Jirawatnotai, Siwanon, Parlow, A. F, Gibori, Geula, Kineman, Rhonda D, Kiyokawa, Hiroaki

“…The lactotroph undergoes dynamic regulation of cell cycle progression during pregnancy, as well as throughout the development of the pituitary. We recently…”
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cdk4 Deficiency Inhibits Skin Tumor Development but Does Not Affect Normal Keratinocyte Proliferation by Rodriguez-Puebla, Marcelo L., Miliani de Marval, Paula L., LaCava, Margaret, Moons, David S., Kiyokawa, Hiroaki, Conti, Claudio J.

“…Most human tumors have mutations that result in deregulation of the cdk4/cyclin-Ink4-Rb pathway. Overexpression of D-type cyclins or cdk4 and inactivation of…”
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Intact Follicular Maturation and Defective Luteal Function in Mice Deficient for Cyclin- Dependent Kinase-4 by Moons, David S, Jirawatnotai, Siwanon, Tsutsui, Tateki, Franks, Roberta, Parlow, A. F, Hales, Dale B, Gibori, Geula, Fazleabas, Asgerally T, Kiyokawa, Hiroaki

“…Cell cycle progression of granulosa cells is critical for ovarian function, especially follicular maturation. During follicular maturation, FSH induces cyclin…”
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Cdk4 Is Indispensable for Postnatal Proliferation of the Anterior Pituitary by Jirawatnotai, Siwanon, Aziyu, Aileen, Osmundson, Evan C., Moons, David S., Zou, Xianghong, Kineman, Rhonda D., Kiyokawa, Hiroaki

“…For proper development and tissue homeostasis, cell cycle progression is controlled by multilayered mechanisms. Recent studies using knock-out mice have shown…”
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Rapamycin Inhibits Growth Factor-Induced Cell Cycle Regulation in Pancreatic β Cells by Aronovitz, Amy, Josefson, Jami, Fisher, Amanda, Newman, Marsha, Hughes, Elizabeth, Chen, Fei, Moons, David S., Kiyokawa, Hiroaki, Lowe, William L.

“…ABSTRACTA progressive decline in islet function is a major obstacle to the success of islet transplantation. The cause of this decline in islet function is…”
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The Cyclin-dependent Kinase Inhibitors p27Kip1 and p21Cip1 Cooperate to Restrict Proliferative Life Span in Differentiating Ovarian Cells by Jirawatnotai, Siwanon, Moons, David S., Stocco, Carlos O., Franks, Roberta, Hales, Dale B., Gibori, Geula, Kiyokawa, Hiroaki

“…The timing of cellular exit from the cell cycle during differentiation is specific for each cell type or lineage. Granulosa cells in the ovary establish…”
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Comparison of noncontrast MRI magnetization transfer and T 2 ‐Weighted signal intensity ratios for detection of bowel wall fibrosis in a Crohn's disease animal model by Dillman, Jonathan R., Swanson, Scott D., Johnson, Laura A., Moons, David S., Adler, Jeremy, Stidham, Ryan W., Higgins, Peter D.R.

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