Search Results - "Moon, R.C"

Prostate intraepithelial neoplasia in Noble rats, a potential intermediate endpoint for chemoprevention studies by Christov, K.T., Moon, R.C., Lantvit, D.D., Boone, C.W., Kelloff, G.J., Steele, V.E., Lubet, R.A., Pezzuto, J.M.

“…In most prostate chemoprevention studies conducted with animal models, the incidence and multiplicity of tumours have been used as endpoints for efficacy…”
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Effect of Deguelin on UVB-Induced Skin Carcinogenesis by Gills, J.J., Kosmeder II, J., Moon, R.C., Lantvit, D.D., Pezzuto, J.M.

“…Nonmelanoma skin cancer afflicts more than one million people in the U.S. annually, highlighting the need for more effective preventive regimens. We have…”
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Comparative aspects of carotenoids and retinoids as chemopreventive agents for cancer by Moon, R C

“…Retinoids are well established chemopreventive agents for experimental carcinogenesis of many target organs including mammary gland, urinary bladder, lung,…”
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Identification of degradation product of deguelin and its stability using liquid chromatography and electrospray/mass spectrometry by Shin, Y.G, Udeani, G.O, Kosmeder, J.W. II, Zhao, G.M, Dagar, S, Onyuksel, H, Moriarty, R.M, Cordell, G.A, Moon, R.C, Kinghorn, A.D

“…The degradation product and its stability of deguelin, a naturally occurring rotenoid and potential cancer chemopreventive agent, was evaluated in several…”
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Enhancement of biological activity by conjugation reactions by Olson, J A, Moon, R C, Anders, M W, Fenselau, C, Shane, B

“…Conjugation reactions, such as the formation of sulfates, glucuronides and amino acid derivatives of biologically active compounds, are classically considered…”
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Secretion of vitamin A and retinol-binding protein into plasma is depressed in rats by N-(4-hydroxyphenyl)retinamide (fenretinide) by Smith, J E, Lawless, D C, Green, M H, Moon, R C

“…In clinical trials the cancer preventive drug N-(4-hydroxyphenyl)retinamide (HPR) markedly lowers plasma concentrations of retinol and retinol-binding protein…”
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Therapeutic effect of N-(4-hydroxyphenyl)retinamide on N-methyl-N-nitrosourea-induced rat mammary cancer by Dowlatshahi, K, Mehta, R G, Thomas, C F, Dinger, N M, Moon, R C

“…Virgin Sprague--Dawley rats received a single i.v. injection of 40 mg N-methyl-N-nitrosourea (MNU)/kg body wt. at 50 days of age. After the first palpable…”
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Metabolism of the chemopreventive retinoid N-(4-hydroxyphenyl)retinamide by mammary gland in organ culture by Mehta, R.G, Hultin, T.A, Moon, R.C

“…N-(4-Hydroxyphenyl)retinamide (4-HPR) is considered to be the most effective chemopreventive retinoid for chemically induced mammary carcinogenesis in rats…”
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Retinoid glucuronides do not interact with retinoid binding proteins by Mehta, R G, Barua, A B, Olson, J A, Moon, R C

“…Retinoid glucuronides have recently been described as water soluble, biologically active retinoids. In mouse mammary gland organ cultures retinoyl glucuronide,…”
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Influence of 15 retinoic acid amides on urinary bladder carcinogenesis in the mouse by Moon, R C, McCormick, D L, Becci, P J, Shealy, Y F, Frickel, F, Paust, J, Sporn, M B

“…A series of experiments was conducted to determine the efficacy of 15 synthetic retinoic acid amides (retinamides) as inhibitors of chemical carcinogenesis of…”
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Anticarcinogenic effects of retinoids in animals by Moon, R C, Mehta, R G

“…Retinoids are effective inhibitors of chemical carcinogenesis in the skin, mammary gland, esophagus, respiratory tract, pancreas, and urinary bladder of…”
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Effects of pretreatment with the retinoid N-(4-hydroxyphenyl)-all-trans-retinamide and phenobarbital on the disposition and metabolism of N-(4-hydroxyphenyl)-all-trans-retinamide in mice by Hultin, T A, McCormick, D L, May, C M, Moon, R C

“…The effects of pretreatment with N-(4-hydroxyphenyl)-all-trans-retinamide (4-HPR) and phenobarbital (PB) on the distribution and metabolism of 4-HPR, and on…”
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Effect of N-(4-hydroxyphenyl) retinamide on food intake, growth, and mammary gland development in rats by Radcliffe, J D, Moon, R C

“…Food intake and growth were depressed during the first week of feeding the anticarcinogenic retinoid N-(4-hydroxyphenyl) retinamide (HPR) at a concentration of…”
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Effect of all-trans-retinoic acid on nuclear RNA polymerase activity in chemically-induced rat mammary tumors by Mehta, R G, Hawthorne, M E, Moon, R C

“…In the present study the effect of all-trans-retinoic acid (RA) on nuclear RNA polymerase activity in N-methyl-N-nitrosourea (MNU)-induced mammary tumors was…”
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Influence of total dose and dose schedule on induction of urinary bladder cancer in the mouse by N-butyl-N-(4-hydroxybutyl)nitrosamine by McCormick, D L, Ronan, S S, Becci, P J, Moon, R C

“…Dose-response relationships in the induction of urinary bladder cancer in male C57BL/6 x DBA/2-F1 (BDF) mice by intragastric instillation of…”
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Effect of increasing doses of estrogen and progesterone on mammary carcinogenesis in the rat by McCormick, G M, Moon, R C

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Inhibition of 1-methyl-1-nitrosourea-induced mammary carcinogenesis in the rat by the retinoid axerophthene by Thompson, H J, Becci, P J, Moon, R C, Sporn, M B, Newton, D L, Brown, C C, Nürrenbach, A, Paust, J

“…The hydrocarbon retinoid, axerophthene, and retinyl acetate were compared for their ability to prevent mammary cancer induced in rats by…”
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